Areas of Focus
- Synthetic Biology, Tissue Engineering and Regenerative Medicine
- Cartilage regeneration and vascularization using single-cell sequencing technologies for tissue repair evaluation, seed cell mechanisms, and in-situ regeneration techniques
- Endothelial cell/stem cell communication and endothelial state transition mechanisms in vascular regeneration
- Development of cross-kingdom synthetic biology tools for engineered prokaryotic and eukaryotic cell construction
Work Experience
- 2001-Present: Lecturer (2001), Associate Researcher (2006), Doctoral Supervisor (2010), Tenured Associate Professor (2016) at Tsinghua University
Academic Background & Achievements
- 1991-1996: Bachelor of Science in Biological Sciences and Technology, Tsinghua University
- 1996-2001: PhD in Biochemistry and Molecular Biology, Tsinghua University
Publications
- Data driven mathematical modeling reveals the dynamic mechanism of MSC-induced neovascularization, Yu YT, Situ QJ, Jia WY, Li JX, Wu Q, Lei JZ, 2019
- Systematic Reconstruction of Molecular Cascades Regulating GP Development Using Single-Cell RNA-Seq, Li JX, Luo HF, Wang R, Lang JD, Zhu SY, Zhang ZM, Fang JH, Qu KK, Lin YT, Long HZ, Yao Y, Tian G, Wu Q, 2016
- RNAe: an effective method for targeted protein translation enhancement by artificial non-coding RNA with SINEB2 repeat, Yao Y, Jin SH, Long HZ, Yu YT, Zhang ZM, Cheng G, Xu CW, Ding Y, Guan Q, Li N, Fu SN, Chen XJ, Yan YB, Zhang HS, Tong P, Tan Y, Yu Y, Fu SS, Li J, He GJ, Wu Q, 2015
- Transcriptional Profiling Reveals Crosstalk Between Mesenchymal Stem Cells and Endothelial Cells Promoting Prevascularization by Reciprocal Mechanisms, Li JX, Ma Y, Teng RF, Guan Q, Lang JD, Fang JH, Long HZ, Tian G, Wu Q, 2015
- A tetracycline expression system in combination with Sox9 for cartilage tissue engineering, Yao Y, He Y, Guan Q, Wu Q, 2014
- MiR-335-5p Promotes Chondrogenesis in Mouse Mesenchymal Stem Cells and Is Regulated Through Two Positive Feedback Loops, Lin X, Wu L, Zhang ZM, Yang RH, Guan Q, Hou XF, Wu Q, 2014
- MicroRNA regulation associated chondrogenesis of mouse MSCs grown on polyhydroxyalkanoates, Yan C, Wang Y, Shen XY, Yang G, Jian J, Wang HS, Chen GQ, Wu Q, 2011
- MicroRNAs in the regulation of interfacial behaviors of MSCs cultured on microgrooved surface pattern, Wang Y, Jiang XL, Yang SC, Lin X, He Y, Yan C, Wu L, Chen GQ, Wang ZY, Wu Q, 2011
- Evaluation of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) conduits for peripheral nerve regeneration, Bian YZ, Wang Y, Aibaidoula G, Chen GQ, Wu Q, 2009
- Evaluation of three-dimensional scaffolds prepared from poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) for growth of allogeneic chondrocytes for cartilage repair in rabbits, Wang Y, Bian Y-Z, Wu Q, Chen G-Q, 2008
Awards
- 2001: First Prize, Beijing Science and Technology Progress Award (Third Contributor) for the development of bioplastic PHBHHx
- 2002: Second Prize, National Technical Invention (Third Contributor) for the development of bioplastic PHBHHx
- 2003: Silver Award, Nuremberg International Invention (Third Contributor) for the development of bioplastic PHBHHx
- 2004: First Prize, Beijing Educational Achievement (Third Contributor)
- 2005: Second Prize, National Higher Education Achievement (Third Contributor) for the development of full-color basic life science textbooks and teaching materials
- 2008: Second Prize, Tsinghua University Excellent Teaching Achievement (Fourth Contributor) for the construction of innovative biology laboratory courses
- 2008: Selected for the Ministry of Education's New Century Excellent Talents Support Plan
- 2012: Second Prize, Beijing Science and Technology Award (Second Contributor) for the basic research on the application of microbial polyhydroxyalkanoates PHA