Professor | Wei Xie | Asia Growth Partners

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Name	Wei Xie
Contact Information	{'en': 'Tel: +86-10-62771496 (Lab)\\nE-mail: xiewei121 AT tsinghua.edu.cn', 'zh': '电话: +86-10-62771496 (实验室)\\n电子邮件: xiewei121 AT tsinghua.edu.cn', 'de': 'Tel: +86-10-62771496 (Labor)\\nE-Mail: xiewei121 AT tsinghua.edu.cn'}
Language ability	English, Chinese
Province	Beijing

Upload Avatar (500 x 500)

Name

Wei Xie

Contact Information

{'en': 'Tel: +86-10-62771496 (Lab)\\nE-mail: xiewei121 AT tsinghua.edu.cn', 'zh': '电话: +86-10-62771496 (实验室)\\n电子邮件: xiewei121 AT tsinghua.edu.cn', 'de': 'Tel: +86-10-62771496 (Labor)\\nE-Mail: xiewei121 AT tsinghua.edu.cn'}

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Tsinghua University
Faculty	Life Sciences
Academic Background & Achievements	1999-2003 Bachelor of Biological Sciences: Peking University 2003-2008 PhD in Molecular Biology: University of California, Los Angeles 2006-2008 Master of Statistics: University of California, Los Angeles
Work Experience	2008-2009 Postdoctoral Researcher: University of California, Los Angeles 2009-2013 Postdoctoral Researcher: Ludwig Cancer Research, University of California, San Diego 2013- Present Assistant Professor, Associate Professor, Professor: Tsinghua University

University/Lab Affiliation and Title

Tsinghua University

Faculty

Life Sciences

Academic Background & Achievements

1999-2003 Bachelor of Biological Sciences: Peking University
2003-2008 PhD in Molecular Biology: University of California, Los Angeles
2006-2008 Master of Statistics: University of California, Los Angeles

Work Experience

2008-2009 Postdoctoral Researcher: University of California, Los Angeles
2009-2013 Postdoctoral Researcher: Ludwig Cancer Research, University of California, San Diego
2013- Present Assistant Professor, Associate Professor, Professor: Tsinghua University

Areas of Focus	Epigenetics, Genomics, Developmental Biology
Publications	Multifaceted SOX2-chromatin interaction underpins pluripotency progression in early embryos, Wei Xie et al., 2023 NR5A2 connects zygotic genome activation to the first lineage segregation in totipotent embryos, Wei Xie et al., 2023 OBOX regulates mouse zygotic genome activation and early development, Wei Xie et al., 2023 Translatome and transcriptome co-profiling reveals a role of TPRXs in human zygotic genome activation, Wei Xie et al., 2022 Ultrasensitive Ribo-seq reveals translational landscapes during mammalian oocyte-to-embryo transition and pre-implantation development, Wei Xie et al., 2022 Evolutionary epigenomic analyses in mammalian early embryos reveal species-specific innovations and conserved principles of imprinting, Wei Xie et al., 2021 The landscape of RNA Pol II binding reveals a step-wise transition during ZGA, Wei Xie et al., 2020 Imprecise DNMT1 activity coupled with neighbor-guided correction enables robust yet flexible epigenetic inheritance, Wei Xie et al., 2020 Epigenomic analysis of gastrulation identifies a unique chromatin state for primed pluripotency, Wei Xie et al., 2019 Resetting histone modifications during human parental-to-zygotic transition, Wei Xie et al., 2019 SETD2 regulates the maternal epigenome and embryonic development, Wei Xie et al., 2019 Chromatin analysis in human early development reveals epigenetic transition during ZGA, Wei Xie et al., 2018 Allelic reprogramming of 3D chromatin architecture during early mammalian development, Wei Xie et al., 2017 Allelic reprogramming of the histone modification H3K4me3 in early mammalian development, Wei Xie et al., 2016 The landscape of accessible chromatin in mammalian preimplantation embryos, Wei Xie et al., 2016

Areas of Focus

Epigenetics, Genomics, Developmental Biology

Publications

Multifaceted SOX2-chromatin interaction underpins pluripotency progression in early embryos, Wei Xie et al., 2023
NR5A2 connects zygotic genome activation to the first lineage segregation in totipotent embryos, Wei Xie et al., 2023
OBOX regulates mouse zygotic genome activation and early development, Wei Xie et al., 2023
Translatome and transcriptome co-profiling reveals a role of TPRXs in human zygotic genome activation, Wei Xie et al., 2022
Ultrasensitive Ribo-seq reveals translational landscapes during mammalian oocyte-to-embryo transition and pre-implantation development, Wei Xie et al., 2022
Evolutionary epigenomic analyses in mammalian early embryos reveal species-specific innovations and conserved principles of imprinting, Wei Xie et al., 2021
The landscape of RNA Pol II binding reveals a step-wise transition during ZGA, Wei Xie et al., 2020
Imprecise DNMT1 activity coupled with neighbor-guided correction enables robust yet flexible epigenetic inheritance, Wei Xie et al., 2020
Epigenomic analysis of gastrulation identifies a unique chromatin state for primed pluripotency, Wei Xie et al., 2019
Resetting histone modifications during human parental-to-zygotic transition, Wei Xie et al., 2019
SETD2 regulates the maternal epigenome and embryonic development, Wei Xie et al., 2019
Chromatin analysis in human early development reveals epigenetic transition during ZGA, Wei Xie et al., 2018
Allelic reprogramming of 3D chromatin architecture during early mammalian development, Wei Xie et al., 2017
Allelic reprogramming of the histone modification H3K4me3 in early mammalian development, Wei Xie et al., 2016
The landscape of accessible chromatin in mammalian preimplantation embryos, Wei Xie et al., 2016

Epigenetics Genomics Developmental Biology Molecular Biology Computational Biology Stem Cell Differentiation Human Disease Gene Regulation Chromatin Transcription

Zhang He - Tongji University

Chong Li - Tongji University

Chen Wang - Tongji University

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