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Guangshuo Ou
Life Science
Tsinghua University
Beijing
Language: English, Chinese
Cell Skeleton
Signal Molecules
Asymmetric Cell Division
Directed Cell Migration
Ciliogenesis
Super-Resolution Live Imaging
Cryo-Electron Microscopy
Conditional Gene Editing
Biochemical Analysis
Model Animals
Areas of Focus
- Cell Biology
- Neural Development
Work Experience
- 2007-2011 Postdoctoral Researcher, University of California, San Francisco/Howard Hughes Medical Institute
- 2011-2013 Researcher and Doctoral Supervisor, Institute of Biophysics, Chinese Academy of Sciences
- 2013-present Professor and Doctoral Supervisor, School of Life Sciences, Tsinghua University
Academic Background & Achievements
- 1994-2001 Bachelor and Master of Science: China Agricultural University
- 2001-2006 PhD in Cell and Developmental Biology: University of California, Davis
Publications
- Optimal Sidestepping of Intraflagellar Transport Kinesins Regulates Structure and Function of Sensory Cilia, Ou G et al., 2020
- Spectrin-based membrane skeleton supports ciliogenesis, Ou G et al., 2019
- Spectraplakin Induces Positive Feedback between Fusogens and the Actin Cytoskeleton to Promote Cell-Cell Fusion, Ou G et al., 2017
- Hippo Kinases Maintain Polarity during Directional Cell Migration in C. elegans, Ou G et al., 2017
- Dynein-Driven Retrograde Intraflagellar Transport Is Triphasic in C. elegans Sensory Cilia, Ou G et al., 2017
- Centriole translocation and degeneration during ciliogenesis in Caenorhabditis elegans neurons, Ou G et al., 2017
- Functional Coordination of WAVE and WASP in C. elegans Neuroblast Migration, Ou G et al., 2016
- Anillin regulates neuronal migration and neurite growth by linking RhoG to the actin cytoskeleton, Ou G et al., 2015
- Conditional Knockouts Generated by Engineered CRISPR-Cas9 Endonuclease Reveal the Roles of Coronin in C. elegans Neural Development, Ou G et al., 2014
- Conditional targeted genome editing using somatically expressed TALENs in C. elegans, Ou G et al., 2013
- Polarized myosin produces unequal size daughters during asymmetric cell division, Ou G et al., 2010
- Functional Coordination of Intraflagellar Transport Motors, Ou G et al., 2005
