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Dan Ying Chen
Life Science
Peking University
Beijing
Language: Chinese, English
Nf-Κb
Transcription Factor
Cell Signaling
Regulatory Mechanisms
Pathogen Infection
Tumor
Cancer
Immune Response
Inflammation
Cell Proliferation
Areas of Focus
- Transcription factor NF-κB activation and its cellular signaling pathways and regulatory mechanisms
Work Experience
- 2004 - Present, Associate Professor, Peking University
- 2000 - 2001, Visiting Scholar, National Jewish Medical and Research Center, University of Colorado
- 1999 - 2004, Lecturer, Peking University
- 1997 - 1999, Teaching Assistant, Peking University
Academic Background & Achievements
- 1999 - 2003 PhD in Cell Biology, Peking University
- 1994 - 1997 Master's in Cell Biology, Peking University
- 1990 - 1994 Bachelor's in Biochemistry, Sichuan University
Publications
- UNC13D inhibits STING signaling by attenuating its oligomerization on the endoplasmic reticulum, Song P*, Yang W, Lou KF, Dong H, Zhang H, Wang B, Chen D*, 2022
- An E3 ligase-independent function for RNF123 in RIG-I like receptors-mediated antiviral signaling, Wang S, Yang YK, Chen T, Zhang H, Yang WW, Song SS, Zhai ZH, Chen DY*, 2016
- Ring finger protein 166 potentiates RNA virus-induced interferon-β production via enhancing the ubiquitination of TRAF3 and TRAF6, Chen HW, Yang YK, Xu H, Yang WW, Zhai ZH, Chen DY*, 2015
- Negative regulation of RIG-I-mediated innate antiviral signaling by SEC14L1, Li MT, Di W, Xu H, Yang YK, Chen HW, Zhang FX, Zhai ZH, Chen DY*, 2013
- ARF-like protein 16 (ARL16) inhibits RIG-I by binding with its C-terminal domain in a GTP-dependent manner, Yang YK, Qu H, Gao D, Di W, Chen HW, Guo X, Zhai ZH, Chen DY*, 2011
- REUL is a novel E3 ubiquitin ligase and stimulator of retinoic-acid-inducible gene-I, Gao D, Yang YK, Wang RP, Zhou X, Diao FC, Li MD, Zhai ZH, Jiang ZF, Chen DY*, 2009
- WDR34 is a novel TAK1-associated suppressor of the IL-1R/TLR3/TLR4-induced NF-kappaB activation pathway, Gao D, Wang R, Li B, Yang Y, Zhai ZH, Chen DY*, 2009
- Syntenin negatively regulates TRAF6-mediated IL-1R/TLR4 signaling, Chen F, Du YJ, Chen G, Zhang Z, Zhang M, Shu HB, Zhai Z, Chen D*, 2008
- Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3, Zhang M, Tian Y, Wang RP, Gao D, Zhang Y, Diao FC, Chen DY*, Zhai ZH, Shu HB*, 2008
Awards
- 2010: Second Class National Natural Science Award (Third Contributor)
- 2007: Peking University Dongbao Teaching Award
- 2006: Second Prize in the Fifth Young Teachers Basic Skills Competition of Peking University
- 2005: First Class National Natural Science Award Recommended by Ministry of Education (Third Contributor)
- 2005: National Outstanding Doctoral Dissertation
- 2003: Second Prize in the Eighth Young Excellent Scientific Paper Award by the Chinese Society for Cell Biology
