Received National Outstanding Youth Science Fund, among other awards and grants
2018-Present Professor, Peking University
2012-2018 Postdoctoral Researcher, Harvard Medical School/Boston Children's Hospital
2010-2012 Visiting Scholar, University of California, Riverside
Young Scientist Award, Chinese Society for Cell Biology, 2024
Young Scientist Award, Asia, 2023
Youth Science and Technology Award, Zhong Nanshan, 2023
Life Science Innovation Breakthrough Award, Zhongyuan Union, 2022
Xiaocheng Gu Lecture Award, 2022
Outstanding Paper Advisor Award, 2022
Outstanding Young Researcher Award, Chinese Society for Stem Cell Biology, 2021
Young Researcher Award, Boehringer Ingelheim, 2021
Teaching Award, Dongbao, 2021
Bayer Scholar Award, 2019
Yifang Scholar, 2019
Harvard Chinese Life Science Research Award, 2016
Outstanding Thesis Award, Peking University, 2012
Research
RNA biology in stem cells and translational medicine Reconstruction of plant or microbial RNA regulatory pathways in animal cells Potential applications of RNA pathways in basic and translational medical research
Capturing totipotency in human cells through spliceosomal repression, Shiyu Li, Min Yang, Hui Shen, Li Ding, Xuehui Lyu, Kexin Lin, Jennie Ong, and Peng Du*, 2024
Hallmarks of totipotent and pluripotent stem cell states, Peng Du* and Jun Wu*, 2024
Spatiotemporal insight of early pregnancy governed by immune-featured stromal cells, Min Yang, Jennie Ong, Fanju Meng, Feixiang Zhang, Hui Shen, Kerstin Kitt, Tengfei Liu, Wei Tao and Peng Du*, 2023
Spatiotemporal transcriptome atlas reveals the regional specification of the developing human brain, Yanxin Li, Zhongqiu Li, Changliang Wang, Min Yang, Ziqing He, Feiyang Wang, Yuehong Zhang, Rong Li, Yunxia Gong, Binhong Wang, Baoguang Fan, Chunyue Wang, Lei Chen, Hong Li, Peifu Shi, Nana Wang, Zhifeng Wei, Yan-Ling Wang, Lei Jin*, Peng Du*, Ji Dong*, and Jianwei Jiao*, 2023
ATM–ESCO2–SMC3 axis promotes 53BP1 recruitment in response to DNA damage and safeguards genome integrity by stabilizing cohesin complex, Jianfeng Fu, Siru Zhou, Huilin Xu, Liming Liao, Hui Shen, Peng Du, and Xiaofeng Zheng*, 2023
miRNA dosage control in development and human disease, Yingzi Cui, Ye Qi, Li Ding, Shuangjin Ding, Zonglin Han, Yangming Wang* and Peng Du*, 2023
A plant immune protein enables broad antitumor response by rescuing microRNA deficiency in cancers, Ye Qi, Li Ding, Siwen Zhang, Shengze Yao, Jennie Ong, Yi Li, Hong Wu, and Peng Du*, 2022
Decoding the temporal and regional specification of microglia in the developing human brain, Yanxin Li, Zhongqiu Li, Min Yang, Feiyang Wang, Yuehong Zhang, Rong Li, Qian Li, Yunxia Gong, Binhong Wang, Baoguang Fan, Chunyue Wang, Lei Chen, Hong Li, Jennie Ong, Zhaoqian Teng, Lei Jin*, Yan-Ling Wang*, Peng Du* and Jianwei Jiao*, 2022
Mouse totipotent stem cells captured and maintained through spliceosomal repression, Hui Shen, Min Yang, Shiyu Li, Jing Zhang, Bing Peng, Chunhui Wang, Zai Chang, Jennie Ong, and Peng Du*, 2021
Global miRNA dosage control of embryonic germ layer specification, Yingzi Cui, Xuehui Lyu, Li Ding, Lan Ke, Dechang Yang, Mehdi Pirouz, Ye Qi, Jennie Ong, Ge Gao, Peng Du*, and Richard Gregory*, 2021
A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts, Bingqing Xie, Da Sun, Yuanyuan Du, Jun Jia, Shicheng Sun, Jun Xu, Yifang Liu, Chengang Xiang, Sitong Chen, Huangfan Xie, Qiming Wang, Guangya Li, Xuehui Lyu, Hui Shen, Shiyu Li, Min Wu, Xiaonan Zhang, Yue Pu, Kuanhui Xiang, Weifeng Lai, Peng Du, Zhenghong Yuan, Cheng Li, Yan Shi, Shichun Lu, Hongkui Deng, 2019
mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis, Junho Choe, Shuibin Lin, Wencai Zhang, Qi Liu, Longfei Wang, Julia Ramirez-Moya, Peng Du, Wantae Kim, Shaojun Tang, Piotr Sliz, Pilar Santisteban, Rani E George, William G Richards, Kwok-Kin Wong, Nicolas Locker, Frank J Slack, Richard I Gregory, 2018
Drosha knockout leads to enhancement of viral titers for vectors encoding miRNA-adapted shRNAs, Hee Ho Park, Robinson Triboulet, Martin Bentler, Swaroopa Guda, Peng Du, Haiming Xu, Richard I Gregory, Christian Brendel, David A Williams, 2018
An intermediate pluripotent state controlled by microRNAs is required for the naive-to-primed stem cell transition, Peng Du, Mehdi Pirouz, Jiho Choi, Aaron J Huebner, Kendell Clement, Alexander Meissner, Konrad Hochedlinger, Richard I Gregory, 2018
Dis3l2-mediated decay is a quality control pathway for noncoding RNAs, Mehdi Pirouz, Peng Du, Marzia Munafò, Richard I Gregory, 2016
METTL3 promotes translation in human cancer cells, Shuibin Lin, Junho Choe, Peng Du, Robinson Triboulet, Richard I Gregory, 2016
A biogenesis step upstream of microprocessor controls miR-17∼92 expression, Peng Du, Longfei Wang, Piotr Sliz, Richard I Gregory, 2015
miRNA-embedded shRNAs for lineage-specific BCL11A knockdown and hemoglobin F induction, Swaroopa Guda, Christian Brendel, Raffaele Renella, Peng Du, Daniel E Bauer, Matthew C Canver, Jennifer K Grenier, Andrew W Grimson, Sophia C Kamran, James Thornton, Helen de Boer, David E Root, Michael D Milsom, Stuart H Orkin, Richard I Gregory, David A Williams, 2015
Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4), James E Thornton, Peng Du, Lili Jing, Ljiljana Sjekloca, Shuibin Lin, Elena Grossi, Piotr Sliz, Leonard I Zon, Richard I Gregory, 2014
Virus infection triggers widespread silencing of host genes by a distinct class of endogenous siRNAs in Arabidopsis, Mengji Cao, Peng Du, Xianbing Wang, Yun-Qi Yu, Yan-Hong Qiu, Wanxiang Li, Amit Gal-On, Changyong Zhou, Yi Li, Shou-Wei Ding, 2014
Viral infection induces expression of novel phased microRNAs from conserved cellular microRNA precursors, Peng Du, Jianguo Wu, Jiayao Zhang, Shuqi Zhao, Hong Zheng, Ge Gao, Liping Wei, Yi Li, 2011