Professor | Jing Hu | Asia Growth Partners

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Name	Jing Hu
Contact Information	{'en': 'Email: jing.hu (AT) pku.edu.cn', 'zh': '电子邮件：jing.hu (AT) pku.edu.cn', 'de': 'E-Mail: jing.hu (AT) pku.edu.cn'}
Language ability	Chinese, English
Province	Beijing

Upload Avatar (500 x 500)

Name

Jing Hu

Contact Information

{'en': 'Email: jing.hu (AT) pku.edu.cn', 'zh': '电子邮件：jing.hu (AT) pku.edu.cn', 'de': 'E-Mail: jing.hu (AT) pku.edu.cn'}

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Life Sciences
Academic Background & Achievements	2009-2015 PhD in Molecular Cancer Biology, Duke University Medical School Doctoral supervisor: Professor Xiaofan Wang Postdoctoral training under Professor Joan Massagué at Memorial Sloan Kettering Cancer Center
Work Experience	2023-present Researcher, Peking University School of Life Sciences 2023-present Researcher, Peking University-Tsinghua University Center for Life Sciences 2021-2023 Senior Research Scientist, Memorial Sloan Kettering Cancer Center 2016-2021 Postdoctoral Fellow, Memorial Sloan Kettering Cancer Center 2015 Postdoctoral Fellow, Duke University
Awards	2023 Bayer Researcher 2023 Yifang Scholar 2020 Society Scholar Award, Memorial Sloan Kettering Cancer Center 2019-2020 Postdoctoral Fellowship, Terri Brodeur Breast Cancer Foundation 2016-2018 Postdoctoral Fellowship, GMTEC’s Metastasis Scholars 2016 Robert J. Fitzgerald Scholar, Duke University

University/Lab Affiliation and Title

Peking University

Faculty

Life Sciences

Academic Background & Achievements

2009-2015 PhD in Molecular Cancer Biology, Duke University Medical School
Doctoral supervisor: Professor Xiaofan Wang
Postdoctoral training under Professor Joan Massagué at Memorial Sloan Kettering Cancer Center

Work Experience

2023-present Researcher, Peking University School of Life Sciences
2023-present Researcher, Peking University-Tsinghua University Center for Life Sciences
2021-2023 Senior Research Scientist, Memorial Sloan Kettering Cancer Center
2016-2021 Postdoctoral Fellow, Memorial Sloan Kettering Cancer Center
2015 Postdoctoral Fellow, Duke University

Awards

2023 Bayer Researcher
2023 Yifang Scholar
2020 Society Scholar Award, Memorial Sloan Kettering Cancer Center
2019-2020 Postdoctoral Fellowship, Terri Brodeur Breast Cancer Foundation
2016-2018 Postdoctoral Fellowship, GMTEC’s Metastasis Scholars
2016 Robert J. Fitzgerald Scholar, Duke University

Areas of Focus	Cancer biology Tumor stem cells Early metastasis regulation
Publications	Stress-induced metastasis: The NET effect, Hu J, 2024 STING inhibits the reactivation of dormant metastasis in lung adenocarcinoma, Hu J, Sánchez-Rivera F, Wang Z, Johnson G, Ho Y, Ganesh K, Umeda S, Gan S, Mujal A, Delconte R, Hampton J, Zhao H, Kottapalli S, de Stanchina E, Iacobuzio-Donahue C, Pe’er D, Lowe S, Sun J, Massagué J, 2023 miR-215 is induced post-transcriptionally via HIF-Drosha complex and mediates glioma-initiating cell adaptation to hypoxia by targeting KDM1B, Hu J, Sun T, Wang H, Chen Z, Wang S, Liu T, Yuan L, Li HR, Wang P, Feng Y, Wang Q, McLendon RE, Friedman AH, Keir ST, Bigner DD, Rathmell J, Fu SD, Li QJ, Wang H, Wang XF, 2016 miR-33a promotes glioma-initiating cell self-renewal via PKA and NOTCH pathways, Wang H, Sun T, Hu J, Zhang R, Rao Y, Wang S, Chen R, McLendon RE, Friedman AH, Keir ST, Bigner DD, Li QJ, Wang H, Wang XF, 2014 The 2023 generation, Achinger-Kawecka J, Correa S, Hu J, Li G, Lindeboom R, Misale S, Monkkonen T, Nirmal A, Prekovic S, Sinha S, Trigos A, Watson C, 2023 Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer, Tello-Lafoz M, Srpan K, Sanchez E, Hu J, Remsik J, Romin Y, Calò A, Hoen D, Bhanot U, Morris L, Boire A, Hsu K, Massagué J, Huse M, Er E, 2021 Regenerative lineages and immune-mediated pruning in lung cancer metastasis, Laughney A, Hu J, Campbell N, Bakhoum S, Setty M, Lavallée V, Xie Y, Masilonis I, Carr A, Allaj V, Mattar M, Rekhtman N, Xavier J, Mazutis L, Poirier J, Rudin C, Pe’er D, Massagué J, 2020 ID1 mediates escape from TGF-β tumor suppression in pancreatic cancer, Huang Y, Hu J, Chen F, Lecomte N, Basnet H, David C, Witkin M, Allen P, Leach S, Hollmann T, Lacobuzio-Donahue, C Massagué J, 2020 Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-β signaling, Aragón E, Wang Q, Zou Y, Morgani S, Ruiz L, Kaczmarska Z, Su J, Torner C, Tian L, Hu J, Shu W, Agrawal S, Gomes T, Márquez J, Hadjantonakis A, Macias M, Massagué J, 2019 Pericyte-Like Spreading by Disseminated Cancer Cells Activates YAP and MRTF for Metastatic Colonization, Er E, Valiente M, Ganesh K, Zou Y, Agrawal S, Hu J, Griscom B, Rosenblum M, Boire A, Brogi E, Giancotti F, Schachner M, Malladi S, Massagué J, 2018 Switching off IMMP2L Signaling Drives Senescence via Simultaneous Metabolic Alteration and Blockage of Cell Death, Yuan L, Zhai L, Qian L, Huang D, Ding Y, Xiang H, Liu X, Thompson W, Liu J, He YH, Chen XQ, Hu J, Kong QP, Tan M, Wang XF, 2018 HIF-miR-215-KDM1B promotes glioma-initiating cell adaptation to hypoxia, Hu J, Wang XF, 2016 Noncoding RNAs Regulating Cancer Signaling Network, Hu J, Markowitz GJ, Wang XF, 2016 Isolation of Glioma-Initiating Cells for Biological Study, Hu J, Markowitz GJ, Wang XF ngs (notochord granular surface) gene encodes a novel type of intermediate filament family protein essential for notochord maintenance in zebrafish, Tong X, Xia Z, Zu Y, Telfer H, Hu J, Yu J, Liu H, Zhang Q, Sodmergen, Lin S, Zhang B, 2013

Areas of Focus

Cancer biology
Tumor stem cells
Early metastasis regulation

Publications

Stress-induced metastasis: The NET effect, Hu J, 2024
STING inhibits the reactivation of dormant metastasis in lung adenocarcinoma, Hu J, Sánchez-Rivera F, Wang Z, Johnson G, Ho Y, Ganesh K, Umeda S, Gan S, Mujal A, Delconte R, Hampton J, Zhao H, Kottapalli S, de Stanchina E, Iacobuzio-Donahue C, Pe’er D, Lowe S, Sun J, Massagué J, 2023
miR-215 is induced post-transcriptionally via HIF-Drosha complex and mediates glioma-initiating cell adaptation to hypoxia by targeting KDM1B, Hu J, Sun T, Wang H, Chen Z, Wang S, Liu T, Yuan L, Li HR, Wang P, Feng Y, Wang Q, McLendon RE, Friedman AH, Keir ST, Bigner DD, Rathmell J, Fu SD, Li QJ, Wang H, Wang XF, 2016
miR-33a promotes glioma-initiating cell self-renewal via PKA and NOTCH pathways, Wang H, Sun T, Hu J, Zhang R, Rao Y, Wang S, Chen R, McLendon RE, Friedman AH, Keir ST, Bigner DD, Li QJ, Wang H, Wang XF, 2014
The 2023 generation, Achinger-Kawecka J, Correa S, Hu J, Li G, Lindeboom R, Misale S, Monkkonen T, Nirmal A, Prekovic S, Sinha S, Trigos A, Watson C, 2023
Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer, Tello-Lafoz M, Srpan K, Sanchez E, Hu J, Remsik J, Romin Y, Calò A, Hoen D, Bhanot U, Morris L, Boire A, Hsu K, Massagué J, Huse M, Er E, 2021
Regenerative lineages and immune-mediated pruning in lung cancer metastasis, Laughney A, Hu J, Campbell N, Bakhoum S, Setty M, Lavallée V, Xie Y, Masilonis I, Carr A, Allaj V, Mattar M, Rekhtman N, Xavier J, Mazutis L, Poirier J, Rudin C, Pe’er D, Massagué J, 2020
ID1 mediates escape from TGF-β tumor suppression in pancreatic cancer, Huang Y, Hu J, Chen F, Lecomte N, Basnet H, David C, Witkin M, Allen P, Leach S, Hollmann T, Lacobuzio-Donahue, C Massagué J, 2020
Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-β signaling, Aragón E, Wang Q, Zou Y, Morgani S, Ruiz L, Kaczmarska Z, Su J, Torner C, Tian L, Hu J, Shu W, Agrawal S, Gomes T, Márquez J, Hadjantonakis A, Macias M, Massagué J, 2019
Pericyte-Like Spreading by Disseminated Cancer Cells Activates YAP and MRTF for Metastatic Colonization, Er E, Valiente M, Ganesh K, Zou Y, Agrawal S, Hu J, Griscom B, Rosenblum M, Boire A, Brogi E, Giancotti F, Schachner M, Malladi S, Massagué J, 2018
Switching off IMMP2L Signaling Drives Senescence via Simultaneous Metabolic Alteration and Blockage of Cell Death, Yuan L, Zhai L, Qian L, Huang D, Ding Y, Xiang H, Liu X, Thompson W, Liu J, He YH, Chen XQ, Hu J, Kong QP, Tan M, Wang XF, 2018
HIF-miR-215-KDM1B promotes glioma-initiating cell adaptation to hypoxia, Hu J, Wang XF, 2016
Noncoding RNAs Regulating Cancer Signaling Network, Hu J, Markowitz GJ, Wang XF, 2016
Isolation of Glioma-Initiating Cells for Biological Study, Hu J, Markowitz GJ, Wang XF
ngs (notochord granular surface) gene encodes a novel type of intermediate filament family protein essential for notochord maintenance in zebrafish, Tong X, Xia Z, Zu Y, Telfer H, Hu J, Yu J, Liu H, Zhang Q, Sodmergen, Lin S, Zhang B, 2013

Cancer Biology Tumor Stem Cells Metastasis Regulation Molecular Mechanisms Dormancy Immune Escape Therapeutic Targets

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