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Lu Jian
luj (AT) pku.edu.cn
Chinese, English
Beijing
Peking University
Life Sciences
  • 2002 - 2008 PhD in Evolutionary Biology, University of Chicago
  • 1999 - 2002 Master of Science in Genetics, Peking University
  • 1995 - 1999 Bachelor of Science in Cell Biology and Genetics, Peking University
  • 2022 - Present, Ministry of Education Yangtze River Scholar Distinguished Professor
  • 2022 - Present, Professor, School of Life Sciences, Peking University
  • 2020 - 2021, Researcher/Long-term Associate Professor, School of Life Sciences, Peking University
  • 2013 - Present, Researcher/Assistant Professor, School of Life Sciences, Peking University
  • 2008 - 2013, Postdoctoral Researcher, Department of Molecular Biology and Genetics, Cornell University
  • 2022 Yangtze River Scholar Distinguished Professor
  • 2021 National Advanced Individual in Science and Technology System Against COVID-19
  • 2020 Peking University COVID-19 Epidemic Hero
  • 2012 National Talent Program Young Project
  • 2006 National Outstanding Self-financed Students Scholarship (Award Amount: $5000)
Molecular evolution and genomics
Mechanisms and evolutionary drivers of protein translation regulation
Genetic and evolutionary mechanisms of environmental adaptation in Drosophila
Molecular evolution and global dynamics of COVID-19 virus
  • The high diversity of SARS-CoV-2-related coronaviruses in pangolins alters potential ecological risks, Peng MS, Li JB, Cai ZF, Liu H, Tang X, Ying R, Zhang JN, Tao JJ, Yin TT, Zhang T, Hu JY, Wu RN, Zhou ZY, Zhang ZG, Yu L, Yao YG, Shi ZL, Lu XM, Lu J, Zhang YP, 2021
  • VarEPS: an evaluation and prewarning system of known and virtual variations of SARS-CoV-2 genomes, Sun Q, Shu C, Shi W, Luo Y, Fan G, Nie J, Bi Yu, Wang Q, Qi J, Lu J, Zhou Y, Shen Z, Meng Z, Zhang X, Yu Z, Gao S, Wu L, Ma J, Hu S, 2021
  • SARS-CoV-2's origin should be investigated worldwide for pandemic prevention, Wu Z, Jin Q, Wu G, Lu J, Li M, Guo D, Lan K, Feng L, Qian Z, Ren L, Tan W, Xu W, Yang W, Wang J, Wang C, 2021
  • On the origin of SARS-CoV-2—The blind watchmaker argument, Wu CI, Wen H, Lu J, Su X, Hughes AC, Zhai W, Chen C, Chen H, Li M, Song S, Qian Z, Wang Q, Chen B, Guo Z, Ruan Y, Lu X, Wei F, Jin L, Kang L, Xue Y, Zhao G, Zhang YP, 2021
  • The concordance between the evolutionary trend and the clinical manifestation of the two SARS-CoV-2 variants, Hu B, Liu R, Tang X, Pan Y, Wang M, Tong Y, Ye G, Shen G, Ying R, Fu A, Li D, Zhao W, Peng J, Guo J, Men D, Yao X, Wang Y, Zhang H, Feng Z, Yu J, Chen L, Deng Z, Lu X, Zhang YP, Li Y, Liu B, Yu L, Li Y, Lu J, Liu T, 2021
  • Evolutionary driving forces of A-to-I editing in metazoans, Duan Y, Tang X, Lu J, 2021
  • Functional and adaptive significance of promoter mutations that affect divergent myocardial expressions of TRIM72 in primates, Feng Y, Xu H, Liu J, Xie N, Gao L, He Y, Yao Y, Lv F, Zhang Y, Lu J, Zhang W, Li CY, Hu X, Yang Z, Xiao RP, 2021
  • Determinants of genome-wide distribution and evolution of uORFs in eukaryotes, Zhang H, Wang Y, Wu X, Tang X, Wu C, Lu J, 2021
  • Evolutionary analysis and lineage designation of SARS-CoV-2 genomes, Tang X, Ying R, Yao X, Li G, Wu C, Tang Y, Li Z, Kuang B, Wu F, Chi C, Du X, Qin Y, Gao S, Hu S, Ma J, Liu T, Pang X, Wang J, Zhao G, Tan W, Zhang Y, Lu X, Lu J, 2021
  • A benchmark and an algorithm for detecting germline transposon insertions and measuring de novo transposon insertion frequencies, Yu T, Huang X, Dou S, Tang X, Luo S, Theurkauf WE, Lu J, Weng Z, 2021
  • A-to-I RNA editing in honeybees shows signals of adaptation and convergent evolution, Duan Y, Dou S, Porath HT, Huang J, Eisenberg E, Lu J, 2021
  • On the founder effect in COVID-19 outbreaks: how many infected travelers may have started them all?, Ruan Y, Luo Z, Tang X, Li G, Wen H, He X, Lu X, Lu J, Wu CI, 2021
  • Combinatorial regulation of gene expression by uORFs and microRNAs in Drosophila, Zhang H, Wang Y, Tang X, Dou S, Sun Y, Zhang Q, Lu J, 2021
  • On the origin and continuing evolution of SARS-CoV-2, Tang X, Wu C, Li X, Song Y, Yao X, Wu X, Duan Y, Zhang H, Wang Y, Qian Z, Cui J, Lu J, 2020
  • The use of SARS-CoV-2-related coronaviruses from bats and pangolins to polarize mutations in SARS-Cov-2, Li T, Tang X, Wu C, Yao X, Wang Y, Lu X, Lu J, 2020
  • The Evolutionary Arms Race between Transposable Elements and piRNAs in Drosophila melanogaster, Luo S, Zhang H, Duan Y, Yao X, Clark AG, Lu J, 2020
  • Function and evolution of upstream ORFs in eukaryotes, Zhang H, Wang YR, Lu J, 2019
  • Recent advances in ribosome profiling for deciphering translational regulation, Wang YR, Zhang H, Lu J, 2019
  • Metazoan tsRNAs: biogenesis, evolution and regulatory functions, Dou SQ, Wang YR, Lu J, 2019
  • Diversification of transposable elements in arthropods and its impact on genome evolution, Wu CC, Lu J, 2019
  • Biosynthetic energy cost for amino acids decreases in cancer evolution, Zhang H, Wang YR, Li J, Chen H, He XL, Zhang HW, Liang H, Lu J, 2018
  • Genome-wide maps of ribosomal occupancy provide insights into adaptive evolution and regulatory roles of uORFs during Drosophila development, Zhang H, Dou SQ, He F, Luo JJ, Wei LP, Lu J, 2018
  • Drosophila tsRNAs preferentially suppress general translation machinery via antisense pairing and participate in cellular starvation response, Luo SQ, He F, Luo JJ, Dou SQ, Wang YR, Guo AN, Lu J, 2018
  • MicroRNA duplication accelerates the recruitment of new targets during vertebrate evolution, Luo JJ, Wang YR, Yuan J, Zhao ZL, Lu J, 2018
  • Linkage of A-to-I RNA editing in metazoans and the impact on genome evolution, Duan YG, Dou SQ, Luo SQ, Zhang H, Lu J, 2018
  • Adaptation of A-to-I RNA editing in Drosophila, Duan YG, Dou SQ, Luo SQ, Zhang H, Lu J, 2017
  • Silencing of transposable elements by piRNAs in Drosophila: an evolutionary perspective, Luo SQ, Lu J, 2017
  • MicroRNAs in the same clusters evolve to coordinately regulate functionally related genes, Wang YR, Luo JJ, Zhang H, Lu J, 2016
  • Differential TGFβ pathway targeting by miR-122 in humans and mice affects liver cancer metastasis, Yin S, Fan Y, Zhang H, Zhao Z, Hao Y, Li J, Sun C, Yang J, Yang Z, Yang X, Lu J, Xi JJ, 2016
  • Suppression of endogenous gene silencing by degradation of normal cytoplasmic RNA in Arabidopsis, Zhang XY, Zhu Y, Liu XD, Hong XY, Xu Y, Zhu P, Shen Y, Ji YS, Wen X, Zhang C, Zhao Q, Wang YC, Lu J, Guo HW, 2015
  • Population genomics analyses of 962 whole genomes of humans reveal natural selection in non-coding regions, Yu FL, Lu J, Liu XM, Gazave E, Chang D, Raj S, Hunter-Zinck H, Blekhman R, Arbiza L, Hout C, Morrison A, Johnson AD, Bis J, Cupp
Molecular Evolution Genomics Gene Regulation Translation Uorf Non-Coding Rna Rna Editing Drosophila Environmental Adaptation Covid-19

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