2004-2009 PhD in Biomedical Sciences, University of Texas Southwestern Medical Center
1999-2003 Bachelor of Science in Biological Sciences, Peking University
Doctoral supervisor: Michael Brown and Joseph Goldstein, Nobel Laureates
2023-Present Dual-appointed Professor, Peking University Third Hospital
2022-Present Boya Distinguished Professor, Peking University
2020-2023 Collaborative Researcher, Beijing Brain Science and Brain-like Research Center
2019-2024 Collaborative Researcher, Shenzhen Bay Laboratory
2017-2022 Boya Young Scholar, Peking University
2015-Present Researcher, McGovern Institute for Brain Research at Peking University
2015-Present Researcher, Joint Center for Life Sciences at Peking University
2015-Present Doctoral Supervisor, School of Life Sciences at Peking University
2011-2015 Postdoctoral Fellow, The Rockefeller University
2009-2011 Postdoctoral Fellow, Genentech Inc.
2021 Major Advances in Chinese Neuroscience
2020 Outstanding PhD Thesis Advisor, Peking University
2018 Outstanding Class Advisor, Peking University
2016 Qiushi Outstanding Young Scholar Award
2015 Tri-Institutional Breakout Prize
Research
Cancer neuroscience Neuroimmunology Neuroimmunometabolism Neurodegenerative diseases and neuroinflammation
Multiple Cancer Cell Types Release LIF and Gal3 to Hijack Neural Signals, Xu Q, Cao Y, Kong F, Liu J, Chen X, Zhao Y, Lai CH, Zhou X, Hu H, Fu W, Chen J, Yang J#, 2024
AIENP-Reinforced DISCO Method for Whole-Tissue Three-Dimensional Reconstruction of Pulmonary Capillaries, Gong X, Chong K, Liu J, Cheng W, Yang J#, Liu B#, 2024
Skin neuropathy and immunomodulation in diseases, Zhang M, Liu T, Yang J#, 2024
Vimentin regulates nuclear segmentation in neutrophils, Liu J, Li Z, Li M, Du W, Baumeister W, Yang J#, Guo Q#, 2023
Cannabinoid receptor 2 signal promotes type 2 immunity in the lung, Liu T, Liu J, Chen H, Zhou X, Fu W, Cao Y, Yang J#, 2023
Neuroanatomy of lymphoid organs: Lessons learned from whole‐tissue imaging studies, Cao Y, Chen H, Yang J#, 2023
3D anatomy of autonomic innervations in immune organs of a non-human primate and the human, Cao Y, Liu T, Zhou X, Fu W, Li J, Yang J#, 2023
Editorial: Neuroimmune interactions in peripheral neuropathy, Yang J#, Yaron A, Liu K, 2022
Enteric glial cells in immunological disorders of the gut, Liu C, Yang J#, 2022
NAD+-dependent mechanism of pathological axon degeneration, Cao Y, Wang Y, Yang J#, 2022
Sarm1-mediated neurodegeneration within the enteric nervous system protects against local inflammation of the colon, Sun Y, Wang Q, Wang Y, Ren W, Cao Y, Li J, Zhou X, Fu W, Yang J#, 2021
Metabolic stress drives sympathetic neuropathy within the liver, Liu K, Yang L, Wang G, Liu J, Zhao X, Wang Y, Li J, Yang J#, 2021
The NAD(+)-mediated self-inhibition mechanism of pro-neurodegenerative SARM1, Jiang Y, Liu T, Lee CH, Chang Q, Yang J#, Zhang Z#, 2020
Local sympathetic innervations modulate the lung innate immune responses, Wang Q, Liu K, Yang L, Wang H, Yang J#, 2020
BoneClear: whole-tissue immunolabeling of the intact mouse bones for 3D imaging of neural anatomy and pathology, Wang Q, Liu K, Yang L, Wang H, Yang J#, 2019
Panicle-Shaped Sympathetic Architecture in the Spleen Parenchyma Modulates Antibacterial Innate Immunity, Ding X, Wang H, Qian X, Han X, Yang L, Cao Y, Wang Q, Yang J#, 2019
Transcriptional mechanism of IRF8 and PU.1 governs microglial activation in neurodegenerative condition, Zhou N, Liu K, Sun Y, Cao Y, Yang J#, 2019
Molecular Mechanism of Wallerian Degeneration, Zhou N, Yang J#, 2017
An axon-T cell feedback loop enhances inflammation and axon degeneration, Liu T, Wang H, Kutsovsky DY, Iskols M, Chen H, Ohn CYJ, Patel N, Yang J, Simon DJ, 2024
The default and directed pathways of hepatoblast differentiation involve distinct epigenomic mechanisms, Yang L, Wang X, Yu XX, Yang L, Zhou BC, Yang J, Xu CR, 2023
Molecular mechanism of substrate recognition by folate transporter SLC19A1, Dang Y, Zhou D, Du X, Zhao H, Lee CH, Yang J, Wang Y, Qin C, Guo Z, Zhang Z, 2022
Specificity of TGF-β1 signal designated by LRRC33 and integrin αVβ8, Duan Z, Lin X, Wang L, Zhen Q, Jiang Y, Chen C, Yang J, Lee CH, Qin Y, Li Y, Zhao B, Wang J, Zhang Z, 2022
Loss of the sympathetic signal produces sterile inflammation of the prostate, Hu H, Cui YW, Yang J, Cao Y, 2022
Meningeal lymphatic vessels mediate neurotropic viral drainage from the central nervous system, Li X, Qi L, Yang D, Hao S, Zhang F, Zhu X, Sun Y, Chen C, Ye J, Yang J, Zhao L, Altmann DM, Cao S, Wang H, Wei B, 2022
Intraperitoneal injection of lithium chloride induces lateralized activation of the insular cortex in adult mice, Qian K, Liu J, Cao Y, Yang J, Qiu S, 2021
A growth-factor-activated lysosomal K(+) channel regulates Parkinson`s pathology, Wie J, Liu Z, Song H, Tropea TF, Yang L, Wang H, Liang Y, Cang C, Aranda K, Lohmann J, Yang J, Lu B, Chen-Plotkin AS, Luk KC, Ren D, 2021
Mutation in ε-Sarcoglycan Induces a Myoclonus-Dystonia Syndrome-Like Movement Disorder in Mice, Li J, Liu Y, Li Q, Huang X, Zhou D, Xu H, Zhao F, Mi X, Wang R, Jia F, Xu F, Yang J, Liu D, Deng X, Zhang Y, 2021
Axon Degeneration Gated by Retrograde Activation of Somatic Pro-apoptotic Signaling, Simon DJ, Pitts J, Hertz NT, Yang J, Yamagishi Y, Olsen O, Tešić Mark M, Molina H, Tessier-Lavigne M, 2016
Pathological axonal death through a MAPK cascade that triggers a local energy deficit, Yang J, Wu Z, Renier N, Simon DJ, Uryu K, Park DS, Greer PA, Tournier C, Davis RJ, Tessier-Lavigne M, 2015
iDISCO: a simple, rapid method to immunolabel large tissue samples for volume imaging, Renier N, Wu Z, Simon DJ, Yang J, Ariel P, Tessier-Lavigne M, 2014
Regulation of axon degeneration after injury and in development by the endogenous calpain inhibitor calpastatin, Yang J, Weimer RM, Kallop D, Olsen O, Wu Z, Renier N, Uryu K, Tessier-Lavigne M, 2013
DLK initiates a transcriptional program that couples apoptotic and regenerative responses to axonal injury, Watkins TA, Wang B, Huntwork-Rodriguez S, Yang J, Jiang Z, Eastham-Anderson J, Modrusan Z, Kaminker JS, Tessier-Lavigne M, Lewcock JW, 2013
A caspase cascade regulating developmental axon degeneration, Simon DJ, Weimer RM, McLaughlin T, Kallop D, Stanger
Area of Focus
Macrophage | Defense | Mechanisms | Intercellular | Communication | Molecular | Pathology | Human | Diseases | Major | Research | Biological | Cellular | Health
