Professor | Chengqi Yi | Asia Growth Partners

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Name	Chengqi Yi
Contact Information	{'en': 'Email: chengqi.yi (AT) pku.edu.cn, Office Phone: 62752895, Lab Phone: 62752895', 'zh': '电子邮件：chengqi.yi (AT) pku.edu.cn, 办公室电话：62752895, 实验室电话：62752895', 'de': 'E-Mail: chengqi.yi (AT) pku.edu.cn, Bürotelefon: 62752895, Labortelefon: 62752895'}
Language ability	English, Chinese
Province	Beijing

Upload Avatar (500 x 500)

Name

Chengqi Yi

Contact Information

{'en': 'Email: chengqi.yi (AT) pku.edu.cn, Office Phone: 62752895, Lab Phone: 62752895', 'zh': '电子邮件：chengqi.yi (AT) pku.edu.cn, 办公室电话：62752895, 实验室电话：62752895', 'de': 'E-Mail: chengqi.yi (AT) pku.edu.cn, Bürotelefon: 62752895, Labortelefon: 62752895'}

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Life Sciences
Academic Background & Achievements	2005 – 2010, PhD in Chemistry, University of Chicago 2001 – 2005, Bachelor of Science in Chemistry, University of Science and Technology of China
Work Experience	2019 - Present, Full Professor, School of Life Sciences, Peking University 2014 - Present, Researcher (Joint Appointment), College of Chemistry and Molecular Engineering, Peking University 2013 - Present, Researcher, Center for Synthetic and Functional Biomolecules, Peking University 2012 - Present, Researcher, Peking-Tsinghua Center for Life Sciences 2017 - 2018, Tenured Associate Professor, School of Life Sciences, Peking University 2012 - 2017, Assistant Professor, School of Life Sciences, Peking University 2010 – 2011, Postdoctoral Researcher, Department of Biochemistry and Molecular Biology, University of Chicago
Awards	8th Chinese Chemical Society - Royal Society of Chemistry Young Chemist Award, 2022 Mao Yisheng Beijing Youth Science and Technology Award, 2022 Zhongyuan Union Life Science Award for Innovation Breakthrough, 2022 National Natural Science Foundation of China Outstanding Youth Science Fund Project, 2018 Ministry of Science and Technology Middle-aged and Young Science and Technology Innovation Leading Talent, 2018 OKeanos-CAPA Young Investigator Award, 2018 Bayer Investigator Award at PKU, 2018 Chinese Chemical Society Award in Chemical Biology for Outstanding Contribution (Under 35), 2018 16th Fok Ying Tung Young Teachers Fund, 2018 10th WuXi AppTec Life Science Research Award Scholar Prize, 2016 Chinese Chemical Society Young Chemist Award, 2016 National Natural Science Foundation of China Excellent Young Scientists Fund Project, 2015 IUPAC Prize for Young Chemists, 2011

University/Lab Affiliation and Title

Peking University

Faculty

Life Sciences

Academic Background & Achievements

2005 – 2010, PhD in Chemistry, University of Chicago
2001 – 2005, Bachelor of Science in Chemistry, University of Science and Technology of China

Work Experience

2019 - Present, Full Professor, School of Life Sciences, Peking University
2014 - Present, Researcher (Joint Appointment), College of Chemistry and Molecular Engineering, Peking University
2013 - Present, Researcher, Center for Synthetic and Functional Biomolecules, Peking University
2012 - Present, Researcher, Peking-Tsinghua Center for Life Sciences
2017 - 2018, Tenured Associate Professor, School of Life Sciences, Peking University
2012 - 2017, Assistant Professor, School of Life Sciences, Peking University
2010 – 2011, Postdoctoral Researcher, Department of Biochemistry and Molecular Biology, University of Chicago

Awards

8th Chinese Chemical Society - Royal Society of Chemistry Young Chemist Award, 2022
Mao Yisheng Beijing Youth Science and Technology Award, 2022
Zhongyuan Union Life Science Award for Innovation Breakthrough, 2022
National Natural Science Foundation of China Outstanding Youth Science Fund Project, 2018
Ministry of Science and Technology Middle-aged and Young Science and Technology Innovation Leading Talent, 2018
OKeanos-CAPA Young Investigator Award, 2018
Bayer Investigator Award at PKU, 2018
Chinese Chemical Society Award in Chemical Biology for Outstanding Contribution (Under 35), 2018
16th Fok Ying Tung Young Teachers Fund, 2018
10th WuXi AppTec Life Science Research Award Scholar Prize, 2016
Chinese Chemical Society Young Chemist Award, 2016
National Natural Science Foundation of China Excellent Young Scientists Fund Project, 2015
IUPAC Prize for Young Chemists, 2011

Areas of Focus	RNA Modification and Epitranscriptomics Gene Editing DNA Modification and Epigenomics
Publications	CRISPR-free, programmable RNA pseudouridylation to suppress premature termination codons, Song J, Dong L, Sun H, Luo N, Huang Q, Li K, Shen X, Jiang Z, Lv Z, Peng L, Zhang M, Wang K, Liu K, Hong J, Yi C, 2023 Absolute quantification of single-base m6A methylation in the mammalian transcriptome using GLORI, Liu C, Sun H, Yi Y, Shen W, Li K, Xiao Y, Li F, Li Y, Hou Y, Lu B, Liu W, Meng H, Peng J, Yi C, Wang J, 2023 Quantitative profiling of pseudouridylation landscape in the human transcriptome, Zhang M, Jiang Z, Ma Y, Liu W, Zhuang Y, Lu B, Li K, Peng J, Yi C, 2023 Mitochondrial base editor induces substantial nuclear off-target mutations, Lei Z, Meng H, Liu L, Zhao H, Rao X, Yan Y, Wu H, Liu M, He A, Yi C, 2022 Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing, Chen L, Zhu B, Ru G, Meng H, Yan Y, Hong M, Zhang D, Luan C, Zhang S, Wu H, Gao H, Bai S, Li C, Ding R, Xue N, Lei Z, Chen Y, Guan Y, Siwko S, Cheng Y, Song G, Wang L, Yi C, Liu M, Li D, 2022 Increasing the efficiency and precision of prime editing with guide RNA pairs, Zhuang Y, Liu J, Wu H, Zhu Q, Yan Y, Meng H, Chen PR, Yi C, 2022 Detect-seq reveals out-of-protospacer editing and target-strand editing by cytosine base editors, Lei Z, Meng H, Lv Z, Liu M, Zhao H, Wu H, Zhang X, Liu L, Zhuang Y, Yin K, Yan Y, Yi C, 2021 Targeting PUS7 suppresses tRNA pseudouridylation and glioblastoma tumorigenesis, Cui Q, Yin K, Zhang X, Ye P, Chen X, Chao J, Meng H, Wei J, Roeth D, Li L, Qin Y, Sun G, Zhang M, Klein J, Huynhle M, Wang C, Zhang L, Badie B, Kalkum M, He C, Yi C, Shi Y, 2021 Landscape and Regulation of m6A and m6Am Methylome across Human and Mouse Tissues, Liu J, Li K, Cai J, Zhang M, Zhang X, Xiong X, Meng H, Xu X, Huang Z, Peng J, Fan J, Yi C, 2020 Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation, Song J, Zhuang Y, Zhu C, Meng H, Lu B, Xie B, Peng J, Li M, Yi C, 2020

Areas of Focus

RNA Modification and Epitranscriptomics
Gene Editing
DNA Modification and Epigenomics

Publications

CRISPR-free, programmable RNA pseudouridylation to suppress premature termination codons, Song J, Dong L, Sun H, Luo N, Huang Q, Li K, Shen X, Jiang Z, Lv Z, Peng L, Zhang M, Wang K, Liu K, Hong J, Yi C, 2023
Absolute quantification of single-base m6A methylation in the mammalian transcriptome using GLORI, Liu C, Sun H, Yi Y, Shen W, Li K, Xiao Y, Li F, Li Y, Hou Y, Lu B, Liu W, Meng H, Peng J, Yi C, Wang J, 2023
Quantitative profiling of pseudouridylation landscape in the human transcriptome, Zhang M, Jiang Z, Ma Y, Liu W, Zhuang Y, Lu B, Li K, Peng J, Yi C, 2023
Mitochondrial base editor induces substantial nuclear off-target mutations, Lei Z, Meng H, Liu L, Zhao H, Rao X, Yan Y, Wu H, Liu M, He A, Yi C, 2022
Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing, Chen L, Zhu B, Ru G, Meng H, Yan Y, Hong M, Zhang D, Luan C, Zhang S, Wu H, Gao H, Bai S, Li C, Ding R, Xue N, Lei Z, Chen Y, Guan Y, Siwko S, Cheng Y, Song G, Wang L, Yi C, Liu M, Li D, 2022
Increasing the efficiency and precision of prime editing with guide RNA pairs, Zhuang Y, Liu J, Wu H, Zhu Q, Yan Y, Meng H, Chen PR, Yi C, 2022
Detect-seq reveals out-of-protospacer editing and target-strand editing by cytosine base editors, Lei Z, Meng H, Lv Z, Liu M, Zhao H, Wu H, Zhang X, Liu L, Zhuang Y, Yin K, Yan Y, Yi C, 2021
Targeting PUS7 suppresses tRNA pseudouridylation and glioblastoma tumorigenesis, Cui Q, Yin K, Zhang X, Ye P, Chen X, Chao J, Meng H, Wei J, Roeth D, Li L, Qin Y, Sun G, Zhang M, Klein J, Huynhle M, Wang C, Zhang L, Badie B, Kalkum M, He C, Yi C, Shi Y, 2021
Landscape and Regulation of m6A and m6Am Methylome across Human and Mouse Tissues, Liu J, Li K, Cai J, Zhang M, Zhang X, Xiong X, Meng H, Xu X, Huang Z, Peng J, Fan J, Yi C, 2020
Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation, Song J, Zhuang Y, Zhu C, Meng H, Lu B, Xie B, Peng J, Li M, Yi C, 2020

Rna Modification Epitranscriptomics Gene Editing Dna Epigenomics Sequencing Transcriptome Methylation Crispr Technology Precision Agriculture Biomedicine Tools Development Innovation Single-Cell Biomarkers Disease Chromatin Accessibility

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