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Jiayu Chen
chenjiayu@tongji.edu.cn
Chinese, English
Shanghai
Tongji University
Life Sciences
  • 2004-2009: Bachelor of Medicine, Fudan University, Shanghai Medical College
  • 2009-2014: PhD in Biochemistry and Molecular Biology, Peking Union Medical College, Beijing Institute of Life Sciences
  • Published research in prestigious journals including Nature and Cell Stem Cell
  • 2023.1-present: Tongji University, School of Life Sciences and Technology, Tenured Professor
  • 2023.11-present: Tongji University Graduate School, Vice Dean
  • 2023.5-2024.5: Tongji University Party Committee Organization Department, Deputy Minister (temporary position)
  • 2021.1-2022.12: Tongji University, School of Life Sciences and Technology, Professor
  • 2017.12-2020.12: Tongji University, School of Life Sciences and Technology, Associate Professor
  • 2014.10-2017.11: Tongji University, School of Life Sciences and Technology, Assistant Professor
  • 2014.2-2014.10: Tongji University Institute of Translational Medicine, Assistant Researcher
  • 2020: National Natural Science Award, Second Prize
  • 2022: Beijing Natural Science Award, First Prize
  • 2019: Ministry of Education Natural Science Award, First Prize
  • 2023: Shanghai May Fourth Youth Group Award
  • 2022: National Excellent Teacher Team Award
  • 2022: Tongji University Graduate 'My Favorite Mentor'
  • 2022: Tongji University Young May Fourth Medal
  • 2020: Tongji University Talent Education Award for Outstanding Teacher
Stem Cells and Cell Reprogramming
Genetics and Epigenetics
Development, Aging, and Disease
Bioinformatics
  • Defining a TFAP2C-centered transcription factor network during murine peri-implantation, Gao R, Yang G, Wang M, Xiao J, Yi S, Huang Y, Guo Z, Kang Y, Fu Q, Wang M, Xu B, Shen S, Zhu Q, Liu M, Wang L, Cui X, Yi S, Kou X, Zhao Y, Gu L, Wang H, Gao S, Jiang C, Chen J, 2024
  • The gonadal niche safeguards human fetal germline cell development following maternal SARS-CoV-2 infection, Shen S, Wang M, Li X, Wang B, Hong W, Li W, Xu B, Guo Z, Han R, Yi S, Wu Z, He X, Wang L, Zhu Q, Yang G, Wang H, Deng Q, Chen J, Gao S, Jiang C, Gao R, 2024
  • Chromatin landscape instructs precise transcription factor regulome during embryonic lineage specification, Wang L, Yi S, Cui X, Guo Z, Wang M, Kou X, Zhao Y, Wang H, Jiang C, Gao S, Yang G, Chen J, Gao R, 2024
  • Effect of SARS-CoV-2 infection in early pregnancy on placental development, Yi S, Wang L, Wang M, Hong W, Xu B, He X, Yang M, Wu Z, Wang B, Yang G, Shen S, Cui X, Wang R, Wang K, Wang H, Li X, Gao S, Jiang C, Chen J, 2024
  • Resetting histone modifications during human prenatal germline development, Gao R, Zeng S, Yang D, Li X, Liu W, Gao Y, Bai D, Zhang L, Chen C, Kang Y, Wang B, Hong W, Wang M, Yin J, Wang H, Deng Q, Gao S, Zhang Y, Chen J, 2023
  • BMP4 preserves the developmental potential of mESCs through Ube2s- and Chmp4b-mediated chromosomal stability safeguarding, Wang M, Zhao K, Liu M, Wang M, Qiao Z, Yi S, Jiang Y, Kou X, Zhao Y, Yin J, Li T, Wang H, Jiang C, Gao S, Chen J, 2022
  • Chromatin architecture reorganization during somatic cell reprogramming, Zhao K, Wang M, Gao S, Chen J, 2021
  • Dux-mediated corrections of aberrant H3K9ac during 2-cell genome activation optimized efficiency of somatic cell nuclear transfer, Guang Y, Zhang L, Liu W, Qiao Z, Shen S, Zhu Q, Gao R, Wang M, Wang M, Li C, Liu M, Sun J, Wang L, Liu W, Cui X, Zhao K, Zang R, Chen M, Liang Z, Wang L, Kou X, Zhao Y, Wang H, Wang Y, Gao S, Chen J, Jiang C, 2021
  • A high-throughput small molecule screen identifies farrerol as a potentiator of CRISPR/Cas9-mediated genome editing, Zhang W, Chen Y, Yang J, Zhang J, Yu J, Wang M, Zhao X, Wei K, Wan X, Xu X, Jiang Y, Chen J, Gao S, Mao Z, 2020
  • The SIRT6 activator MDL-800 improves genomic stability and pluripotency of old murine-derived iPS cells, Chen Y, Chen J, Sun X, Yu J, Qian Z, Wu L, Xu X, Wan X, Jiang Y, Zhang J, Gao S, Mao Z, 2020
  • Mammalian haploid stem cells: establishment, engineering and applications, He W, Chen J, Gao S, 2019
  • Stella safeguards the oocyte methylome by preventing de novo methylation mediated by DNMT1, Li Y, Zhang Z, Chen J, Liu W, Lai W, Liu B, Li X, Liu L, Xu S, Dong Q, Wang M, Duan X, Tan J, Zheng Y, Zhang P, Fan G, Wong J, Xu G, Wang Z, Wang H, Gao S, Zhu B, 2018
  • Esrrb plays important roles in maintaining self-renewal of trophoblast stem cells (TSCs) and reprogramming somatic cells to induced TSCs, Gao H, Gao R, Zhang L, Xiu W, Zang R, Wang H, Zhang Y, Chen J, Gao Y, Gao S, 2019
  • Accurate annotation of accessible chromatin in mouse and human primordial germ cells, Li J, Shen S, Chen J, Liu W, Li X, Zhu Q, Wang B, Chen X, Wu L, Wang M, Gu L, Wang H, Yin J, Jiang C, Gao S, 2018
  • Reduced Self-Diploidization and Improved Survival of Semi-cloned Mice Produced from Androgenetic Haploid Embryonic Stem Cells through Overexpression of Dnmt3b, He W, Zhang X, Zhang Y, Zheng W, Xiong Z, Hu X, Wang M, Zhang L, Zhao K, Qiao Z, Lai W, Lv C, Kou X, Zhao Y, Yin J, Liu W, Jiang Y, Chen M, Xu R, Le R, Li C, Wang H, Wan X, Wang H, Han Z, Jiang C, Gao S, Chen J, 2018
  • Additive-effect pattern of both ZP2 and ZP3 in human and mouse, Liu W, Bai D, Chen J, Gao S, 2017
  • Dosage effects of ZP2 and ZP3 heterozygous mutations cause human infertility, Liu W, Li K, Bai D, Yin J, Tang Y, Chi F, Zhang L, Wang Y, Pan J, Liang S, Guo Y, Ruan J, Kou X, Zhao Y, Wang H, Chen J, Teng X, Gao S, 2017
  • Direct induction of neural progenitor cells transiently passes through a partially reprogrammed state, Gao R, Xiu W, Zhang L, Zang R, Yang L, Wang C, Wang M, Wang M, Yi L, Tang Y, Gao Y, Wang H, Xi J, Liu W, Wang Y, Wen X, Yu Y, Zhang Y, Chen L, Chen J, Gao S, 2017
  • Maternal Sall4 Is Indispensable for Epigenetic Maturation of Mouse Oocytes, Xu K, Chen X, Yang H, Xu Y, He Y, Wang C, Huang H, Liu B, Liu W, Li J, Kou X, Zhao Y, Zhao K, Zhang L, Hou Z, Wang H, Wang H, Li J, Fan H, Wang F, Gao Y, Zhang Y, Chen J, Gao S, 2017
  • The combination of Tet1 with Oct4 generates high-quality mouse induced pluripotent stem cells (iPSCs), Chen J, Gao Y, Huang H, Xu K, Chen X, Jiang Y, Li H, Gao S, Tao
Stem Cells Reprogramming Genetics Epigenetics Development Aging Disease Bioinformatics Cell Biology Molecular Biology

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