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Hongbing Wang
Life Science
Tongji University
Shanghai
Language: Chinese, English
Small Molecules
Natural Drugs
Aging
Molecular Biology
Neurodegeneration
Pathogenesis
Drug Discovery
Mechanism Of Action
Age-Related Diseases
Biological Research
Areas of Focus
- Natural small molecule drugs
- Aging biology
- Molecular biology of aging based on small molecule probes
- Pathogenesis of neurodegenerative diseases
- Discovery and mechanism of action of natural active drugs for delaying aging and treating age-related diseases
Work Experience
- 2004-07 to 2009-08 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences: Assistant Researcher, Associate Researcher
- 2009 onwards - Tongji University: Associate Professor, Professor
Academic Background & Achievements
- 1998 - Bachelor's Degree: China Pharmaceutical University
- 2001 - Master's Degree: Tianjin University
- 2004 - PhD: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
- Published over 50 research papers, 40+ indexed by SCI
- Filed 1 international patent and 5 Chinese patents (3 granted)
Publications
- Liensinine and neferine exert neuroprotective effects via the autophagy pathway in transgenic Caenorhabditis elegans, Wu MC, Gao YH, Zhang C, Ma BT, Lin HR, Jiang JY, Xue MF, Li S, Wang HB*, 2023
- Autophagy Regulation Influences β-Amyloid Toxicity in Transgenic Caenorhabditis elegans, Lin, H.; Gao, Y.; Zhang, C.; Ma, B.; Wu, M.; Cui, X.; Wang, H. *, 2022
- Polygonum multiflorum Thunb extract extended the lifespan and healthspan of Caenorhabditis elegans via DAF-16/SIR-2.1/SKN-1, Sun, M. L.; Chen, X. Y.; Cao, J. J.; Cui, X. H.; Wang, H. B. *, 2021
- Essential Oil of Acorus tatarinowii Schott Ameliorates Aβ-Induced Toxicity in Caenorhabditis elegans through an Autophagy Pathway, Chen, X. Y.; Liao, D. C.; Sun, M. L.; Cui, X. H.; Wang, H. B. *, 2020
- Lonicera japonica extends lifespan and healthspan in Caenorhabditis elegans, Zhen-Zhou Yang, Ying-Ting Yu, Hong-Ru Lin, De-Chun Liao, Xiang-Huan Cui, Hong-Bing Wang*, 2018
- Lignans from the roots of Acorus tatarinowii Schott ameliorate β amyloid-induced toxicity in transgenic Caenorhabditis elegans, Xiao-Hua Luo, Ying-Ying Zhang, Xin-Yan Chen, Meng-Lu Sun, Shan Li, Hong-Bing Wang*, 2016
- Tigliane Diterpenoids from the Euphorbiaceae and Thymelaeaceae, Hong-Bing Wang*, Xiao-Yang Wang, Li-Ping Liu, Guo-Wei Qin, Ting-Guo Kang, 2015
- Selective Elevation of Adiponectin Production by the Natural Compounds Derived from a Medicinal Herb Alleviates Insulin Resistance and Glucose Intolerance in Obese Mice, Ai-min Xu*, Hong-Bing Wang, Guo-wei Qin, et al., 2009
- Acacetin, a Natural Flavone, Selectively Inhibits Human Atrial Repolarization Potassium Currents and Prevents Atrial Fibrillation in Dogs, Gui-Rong Li*, Hong-Bing Wang, Guo-Wei Qin, et al., 2008
Awards
- 2011: Second Prize in Young Teacher Lecture Competition at Tongji University, Best Style Award
