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Wen Chen
Life Science
Tongji University
Shanghai
Language: Chinese, English
Stem Cells
Neurology
Fetal Development
Epigenetic Regulation
Neurogenesis
Cognition
Dna Repair
Gene Expression
Cell Differentiation
Neural Stem Cells
Areas of Focus
- Stem cells and fetal-origin neurological diseases
Work Experience
- 2017 - Present: Tongji University, School of Life Sciences and Technology, Associate Professor / Master's Supervisor
Academic Background & Achievements
- 2010 - PhD: Chinese Academy of Sciences (State Key Laboratory of Stem Cell and Reproductive Biology)
- 2011 - Recognized as Outstanding Young Talent at Tongji University
- 2015 - Selected for the Young Teacher Talent Training Program at Tongji University
Publications
- Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring, Chen W, Liu N, Shen S, Zhu W, Qiao J, Chang S, Dong J, Bai M, Ma L, Wang S, Jia W, Guo X, Li A, Xi J, Jiang C, Kang J, 2021
- Sirt6 promotes DNA End Joining in iPSCs derived from old mice, Chen W, Liu N, Zhang H, Zhang H, Qiao J, Jia W, Zhu S, Mao Z, Kang J, 2017
- NRG1 knockdown rescues PV interneuron GABAergic maturation deficits and schizophrenia behaviors in fetal growth restriction mice, Dong J, Chen W, Liu N, Chang S, Zhu W, Kang J, 2022
- Sirt7-p21 signaling pathway mediates glucocorticoid induced inhibition of mouse neural stem cell proliferation, Alnoud MAH, Chen W, Liu N, Zhu W, Qiao J, Chang S, Wu Y, Wang S, Yang Y, Sun Q, Kang J, 2021
- MicroRNA-153 improves the neurogenesis of neural stem cells and enhances the cognitive ability of aged mice through the notch signaling pathway, Qiao J, Zhao J, Chang S, Sun Q, Liu N, Dong J, Chen Y, Yang D, Ye D, Liu X, Yu Y, Chen W, Zhu S, Wang G, Jia W, Xi J, Kang J, 2020
- N6-Methyladenosine modification of lincRNA 1281 is critically required for mESC differentiation potential, Yang D, Qiao J, Wang G, Lan Y, Li G, Guo X, Xi J, Ye D, Zhu S, Chen W, Jia W, Leng Y, Wan X, Kang J, 2018
- An HDAC2-TET1 switch at distinct chromatin regions significantly promotes the maturation of pre-iPS to iPS cells, Wei T, Chen W, Wang X, Zhang M, Chen J, Zhu S, Chen L, Yang D, Wang G, Jia W, Yu Y, Duan T, Wu M, Liu H, Gao S, Kang J, 2015
