Professor | Hua Gu | Asia Growth Partners

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Name	Hua Gu
Contact Information	Gu_hua@mail.tongji.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Hua Gu

Contact Information

Gu_hua@mail.tongji.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	1997 - Bachelor of Science in Biochemistry from East China University of Science and Technology 2002 - Master's degree in Biochemistry and Molecular Biology from Fudan University 2009 - PhD in Biomedical Engineering from Tongji University
Work Experience	2009-2011 - Postdoctoral Research at Louisiana State University Health Sciences Center, USA 2011-present - Member of Professor Fang Jianmin's research group at Tongji University
Awards	2020-2021: Advanced Individual in Undergraduate Admissions Work at Tongji University 2021: Advanced Individual in Women's Work at Tongji University 2019: Model Family Award at Tongji University 2019: Third Prize in Teaching Achievement at Tongji University 2017: Talent Fund for Female Teachers at Tongji University 2017: Second Prize in Teaching Achievement at Tongji University 2014: First Prize in Teaching Achievement at Shanghai Municipal Level 2014: Advanced Individual in Class Teacher Work at Tongji University 2013: Outstanding Contribution Award in Class Teacher Work at Tongji University 2012: Third Prize in Young Teacher Teaching Competition at School of Life Science and Technology 2009: First Prize in Young Teacher Teaching Competition at School of Life Science and Technology

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

1997 - Bachelor of Science in Biochemistry from East China University of Science and Technology
2002 - Master's degree in Biochemistry and Molecular Biology from Fudan University
2009 - PhD in Biomedical Engineering from Tongji University

Work Experience

2009-2011 - Postdoctoral Research at Louisiana State University Health Sciences Center, USA
2011-present - Member of Professor Fang Jianmin's research group at Tongji University

Awards

2020-2021: Advanced Individual in Undergraduate Admissions Work at Tongji University
2021: Advanced Individual in Women's Work at Tongji University
2019: Model Family Award at Tongji University
2019: Third Prize in Teaching Achievement at Tongji University
2017: Talent Fund for Female Teachers at Tongji University
2017: Second Prize in Teaching Achievement at Tongji University
2014: First Prize in Teaching Achievement at Shanghai Municipal Level
2014: Advanced Individual in Class Teacher Work at Tongji University
2013: Outstanding Contribution Award in Class Teacher Work at Tongji University
2012: Third Prize in Young Teacher Teaching Competition at School of Life Science and Technology
2009: First Prize in Young Teacher Teaching Competition at School of Life Science and Technology

Areas of Focus	Antitumor and autoimmune disease biopharmaceutical development Molecular regulation of tumor angiogenesis
Publications	Reversing PD-1 Resistance in B16F10 Cells and Recovering Tumour Immunity Using a COX2 Inhibitor, Hua Gu* and Jianmin Fang, 2022 A Novel Anti-B7-H3 × Anti-CD3 Bispecific Antibody with Potent Antitumor Activity, Hua Gu and Jianmin Fang, 2022 Adaptive resistance in tumors to anti-PD-1 therapy through re-immunosuppression by upregulation of GPNMB expression, Hua Gu, Jianmin Fang , 2021 A HER2 target antibody drug conjugate combined with anti-PD-(L)1 treatment eliminates hHER2+ tumors in hPD-1 transgenic mouse model and contributes immune memory formation, Hua Gu, Jianmin Fang , 2021 Suppression of c-Met-Overexpressing Tumors by a Novel c-Met/CD3 Bispecific Antibody, Hua Gu, Jianmin Fang, 2020 Improved recombinant protein production by regulation of transcription and protein transport in Chinese hamster ovary cells, Hua Gu, Jianmin Fang, 2019 CD89-mediated recruitment of macrophages via a bispecific antibody enhances anti-tumor efficacy, Hua Gu* , Jianmin Fang, 2018 Protein phosphatase-1 inhibitor-2 is a novel memory suppressor, Hua Gu, Angus C Nairn, Ya-Ping Tang, Paul J. Colombo, Houhui Xia, 2015 cAMP/PKA pathways and S56 phosphorylation are involved in AA/PGE2-induced increases in rNaV1.4 current, Hua Gu, Yan-Jia Fang, dong-dong Liu, Ping Chen, Yan-Ai Mei*, 2015 The Rac1 inhibitor NSC23766 suppresses CREB signaling by targeting NMDA receptor function, Hua Gu, Benjamin A.Siddoway, Benjamin J. Hall, Pablo E. Castillo, Houhui Xia, 2014 Modulation of muscle rNa V1.4 Na+ channel isoform by arachidonic acid and its non-metabolized analog, Hua Gu, Y. J.He, Y. L.Sun, J.Zhu, J.Mei, Y. A., 2009

Areas of Focus

Antitumor and autoimmune disease biopharmaceutical development
Molecular regulation of tumor angiogenesis

Publications

Reversing PD-1 Resistance in B16F10 Cells and Recovering Tumour Immunity Using a COX2 Inhibitor, Hua Gu* and Jianmin Fang*, 2022
A Novel Anti-B7-H3 × Anti-CD3 Bispecific Antibody with Potent Antitumor Activity, Hua Gu* and Jianmin Fang*, 2022
Adaptive resistance in tumors to anti-PD-1 therapy through re-immunosuppression by upregulation of GPNMB expression, Hua Gu*, Jianmin Fang *, 2021
A HER2 target antibody drug conjugate combined with anti-PD-(L)1 treatment eliminates hHER2+ tumors in hPD-1 transgenic mouse model and contributes immune memory formation, Hua Gu*, Jianmin Fang *, 2021
Suppression of c-Met-Overexpressing Tumors by a Novel c-Met/CD3 Bispecific Antibody, Hua Gu*, Jianmin Fang*, 2020
Improved recombinant protein production by regulation of transcription and protein transport in Chinese hamster ovary cells, Hua Gu, Jianmin Fang*, 2019
CD89-mediated recruitment of macrophages via a bispecific antibody enhances anti-tumor efficacy, Hua Gu* , Jianmin Fang*, 2018
Protein phosphatase-1 inhibitor-2 is a novel memory suppressor, Hua Gu, Angus C Nairn, Ya-Ping Tang, Paul J. Colombo, Houhui Xia, 2015
cAMP/PKA pathways and S56 phosphorylation are involved in AA/PGE2-induced increases in rNaV1.4 current, Hua Gu*, Yan-Jia Fang, dong-dong Liu, Ping Chen, Yan-Ai Mei*, 2015
The Rac1 inhibitor NSC23766 suppresses CREB signaling by targeting NMDA receptor function, Hua Gu, Benjamin A.Siddoway, Benjamin J. Hall, Pablo E. Castillo, Houhui Xia, 2014
Modulation of muscle rNa V1.4 Na+ channel isoform by arachidonic acid and its non-metabolized analog, Hua Gu, Y. J.He, Y. L.Sun, J.Zhu, J.Mei, Y. A., 2009

Biopharmaceuticals Antitumor Autoimmune Diseases Drug Development Molecular Biology Angiogenesis Tumor Vascular Molecular Regulation Research

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