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Zheng Wei
Life Science
Central South University
Hunan
Language: Chinese, English
Genetics
Embryology
Pre-Implantation
Embryo Arrest
Non-Invasive
Predictive Models
Reproductive Technology
High-Throughput Sequencing
Bioinformatics
Pathogenic Genes
Areas of Focus
- Genetic etiology of pre-implantation embryonic arrest
- Non-invasive models for predicting pre-implantation embryo quality
Work Experience
- 2015-2022: Associate Researcher at Xiangya Hospital of Reproductive Genetics
- 2022-present: Distinguished Associate Professor at School of Life Sciences, Central South University
Academic Background & Achievements
- 2009-2015: PhD in Genetics, University of Science and Technology of China
- 2005-2009: Bachelor in Biological Sciences, Central South University
- Recipient of multiple national and provincial research grants
Publications
- Homozygous Mutations in BTG4 Cause Zygotic Cleavage Failure and Female Infertility, Zheng W, et al., 2020
- Dynamics and clinical relevance of maternal mRNA clearance during the oocyte-to-embryo transition in humans, Sha Q-Q, Zheng W, et al., 2020
- Biallelic mutations in MOS cause female infertility characterized by human early embryonic arrest and fragmentation, Zhang YL, Zheng W, et al., 2021
- Homozygous pathogenic variants in ACTL9 cause fertilization failure and male infertility in humans and mice, Dai J, Zheng W, et al., 2021
- IQCN disruption causes fertilization failure and male infertility due to manchette assembly defect, Dai J, Zheng W, et al., 2022
- Dynamic mRNA degradome analyses indicate a role of histone H3K4 trimethylation in association with meiosis-coupled mRNA decay in oocyte aging, Wu Y-W, Zheng W, et al., 2022
- Biallelic variants in MOS cause large polar body in oocyte and human female infertility, Zhang Y-L, Zheng W, et al., 2022
- Biallelic variants in ZFP36L2 cause female infertility characterised by recurrent preimplantation embryo arrest, Zheng W, et al., 2022
- Pathogenic variant in ACTL7A causes severe teratozoospermia characterized by bubble-shaped acrosomes and male infertility, Dai J, Zheng W, et al., 2022
- An increase of phosphatidylcholines in follicular fluid implies attenuation of embryo quality on day 3 post-fertilization, Wang J, Zheng W, et al., 2021
- The comprehensive variant and phenotypic spectrum of TUBB8 in female infertility, Zheng W, et al., 2021
- Expanding the genetic and phenotypic spectrum of the subcortical maternal complex genes in recurrent preimplantation embryonic arrest, Zheng W, et al., 2021
- Non-invasive Metabolomic Profiling of Embryo Culture Medium Using Raman Spectroscopy With Deep Learning Model Predicts the Blastocyst Development Potential of Embryos, Zheng W, et al., 2021
- New biallelic mutations in PADI6 cause recurrent preimplantation embryonic arrest characterized by direct cleavage, Zheng W, et al., 2020
