Professor | Jiada Li | Asia Growth Partners

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Name	Jiada Li
Contact Information	lijiada@csu.edu.cn
Language ability	Chinese, English
Province	Hunan

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Name

Jiada Li

Contact Information

lijiada@csu.edu.cn

Language ability

Chinese, English

Province

Hunan

University/Lab Affiliation and Title	Central South University
Faculty	Life Sciences
Academic Background & Achievements	1989-1993 Bachelor of Science in Biochemistry, Lanzhou University 1996-2001 Doctor of Science in Biochemistry and Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
Work Experience	1993-1996 Assistant, Biochemistry Teaching and Research Department, Hengyang Medical College, Nanhua University 2001-2009 Postdoctoral Researcher, University of California, Irvine, USA 2009-present Professor, School of Life Sciences, Central South University
Awards	2010 Furong Scholar Distinguished Professor, Hunan Province 2011 New Century Excellent Talents in University, Ministry of Education 2016 Outstanding Scientific and Technological Worker of Hunan Province 2016 First Prize of Natural Science, Hunan Province (Ranked fourth) 2021 Outstanding Graduate Supervisor, Hunan Province

University/Lab Affiliation and Title

Central South University

Faculty

Life Sciences

Academic Background & Achievements

1989-1993 Bachelor of Science in Biochemistry, Lanzhou University
1996-2001 Doctor of Science in Biochemistry and Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences

Work Experience

1993-1996 Assistant, Biochemistry Teaching and Research Department, Hengyang Medical College, Nanhua University
2001-2009 Postdoctoral Researcher, University of California, Irvine, USA
2009-present Professor, School of Life Sciences, Central South University

Awards

2010 Furong Scholar Distinguished Professor, Hunan Province
2011 New Century Excellent Talents in University, Ministry of Education
2016 Outstanding Scientific and Technological Worker of Hunan Province
2016 First Prize of Natural Science, Hunan Province (Ranked fourth)
2021 Outstanding Graduate Supervisor, Hunan Province

Areas of Focus	Genetic regulation mechanisms of neurodevelopmental disorders
Publications	Cry1Δ11 mutation induces ADHD-like symptoms through hyperactive dopamine D1 receptor signaling, Liu D, Xie Z, Gu P, Li X, Zhang Y, Wang X, Chen Z, Deng S, Shu Y, Li JD, 2023 CNTNAP2 intracellular domain (CICD) generated by γ-secretase cleavage improves autism-related behaviors, Zhang J, Cai F, Lu R, Xing X, Xu L, Wu K, Gong Z, Zhang Q, Zhang Y, Xing M, Song W, Li JD, 2023 RNF216 regulates meiosis and PKA stability in the testes, Li D, Li F, Meng L, Wei H, Zhang Q, Jiang F, Chen DN, Li W, Tan YQ, Li JD, 2021 Necdin regulates BMAL1 stability and circadian clock through SGT1-HSP90 chaperone machinery, Lu R, Dong Y, Li JD, 2020 Prevalence and associated phenotypes of DUSP6, IL17RD and SPRY4 variants in a large Chinese cohort with isolated hypogonadotropic hypogonadism, Men M, Wang X, Wu J, Zeng W, Jiang F, Zheng R, Li JD, 2020 Phenotypic spectrum of idiopathic hypogonadotropic hypogonadism patients with CHD7 variants from a large Chinese cohort, Li JD, Wu J, Zhao Y, Wang X, Jiang F, Hou Q, Chen DN, Zheng R, Yu R, Zhou W, Men M, 2019 PROKR2 mutations in idiopathic hypogonadotropic hypogonadism: selective disruption of the binding to a Gα-protein leads to biased signaling, Zhao Y, Wu J, Jia H, Wang X, Zheng R, Jiang F, Chen DN, Chen Z, Li JD, 2019 CirGRDB: a database for the genome-wide deciphering circadian genes and regulators, Li X, Shi L, Zhang K, Wei W, Liu Q, Mao F, Li J, Cai W, Chen H, Teng H, Li J, Sun Z, 2018 Functional Rescue of Kallmann Syndrome-associated Prokineticin Receptor 2 (PKR2) Mutants Deficient in Trafficking, Chen DN, Ma YT, Liu H, Zhou QY, Li JD, 2014 Disease-causing Mutation in PKR2 Receptor Reveals a Critical Role of Positive Charges in the Second Intracellular Loop for G-protein Coupling and Receptor Trafficking, Peng Z, Tang Y, Luo H, Jiang F, Yang J, Sun L, Li JD, 2011 Disruption of the circadian output molecule prokineticin 2 results in anxiolytic and antidepressant-like effects in mice, Li JD, Hu WP, Zhou QY, 2009 Attenuated Circadian Rhythms in Mice Lacking the Prokineticin 2 Gene, Li JD, Hu WP, Boehmer L, Cheng MY, Lee AG, Jilek A, Siegel JM, Zhou QY, 2006 Dependence of olfactory bulb neurogenesis on prokineticin 2 signaling, Ng KL, Li JD, Cheng MY, Leslie FM, Lee AG, Zhou QY, 2005

Areas of Focus

Genetic regulation mechanisms of neurodevelopmental disorders

Publications

Cry1Δ11 mutation induces ADHD-like symptoms through hyperactive dopamine D1 receptor signaling, Liu D, Xie Z, Gu P, Li X, Zhang Y, Wang X, Chen Z, Deng S, Shu Y, Li JD*, 2023
CNTNAP2 intracellular domain (CICD) generated by γ-secretase cleavage improves autism-related behaviors, Zhang J, Cai F, Lu R, Xing X, Xu L, Wu K, Gong Z, Zhang Q, Zhang Y, Xing M, Song W*, Li JD*, 2023
RNF216 regulates meiosis and PKA stability in the testes, Li D, Li F, Meng L, Wei H, Zhang Q, Jiang F, Chen DN, Li W*, Tan YQ*, Li JD*, 2021
Necdin regulates BMAL1 stability and circadian clock through SGT1-HSP90 chaperone machinery, Lu R, Dong Y, Li JD*, 2020
Prevalence and associated phenotypes of DUSP6, IL17RD and SPRY4 variants in a large Chinese cohort with isolated hypogonadotropic hypogonadism, Men M, Wang X, Wu J, Zeng W, Jiang F, Zheng R*, Li JD*, 2020
Phenotypic spectrum of idiopathic hypogonadotropic hypogonadism patients with CHD7 variants from a large Chinese cohort, Li JD, Wu J, Zhao Y, Wang X, Jiang F, Hou Q, Chen DN, Zheng R, Yu R, Zhou W, Men M*, 2019
PROKR2 mutations in idiopathic hypogonadotropic hypogonadism: selective disruption of the binding to a Gα-protein leads to biased signaling, Zhao Y, Wu J, Jia H, Wang X, Zheng R, Jiang F, Chen DN, Chen Z*, Li JD*, 2019
CirGRDB: a database for the genome-wide deciphering circadian genes and regulators, Li X, Shi L, Zhang K, Wei W, Liu Q, Mao F, Li J, Cai W, Chen H, Teng H*, Li J*, Sun Z*, 2018
Functional Rescue of Kallmann Syndrome-associated Prokineticin Receptor 2 (PKR2) Mutants Deficient in Trafficking, Chen DN, Ma YT, Liu H, Zhou QY, Li JD*, 2014
Disease-causing Mutation in PKR2 Receptor Reveals a Critical Role of Positive Charges in the Second Intracellular Loop for G-protein Coupling and Receptor Trafficking, Peng Z, Tang Y, Luo H, Jiang F, Yang J, Sun L, Li JD*, 2011
Disruption of the circadian output molecule prokineticin 2 results in anxiolytic and antidepressant-like effects in mice, Li JD, Hu WP, Zhou QY*, 2009
Attenuated Circadian Rhythms in Mice Lacking the Prokineticin 2 Gene, Li JD, Hu WP, Boehmer L, Cheng MY, Lee AG, Jilek A, Siegel JM, Zhou QY*, 2006
Dependence of olfactory bulb neurogenesis on prokineticin 2 signaling, Ng KL, Li JD, Cheng MY, Leslie FM, Lee AG, Zhou QY*, 2005

Genetics Biochemistry Molecular Biology Electrophysiology Behavioral Science Autism Adhd Gnrh Deficiency Molecular Pathology Therapeutic Targets

Jiada Li - Central South University

Yuan Xiaobing - East China Normal University

Hui Guo - Central South University

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