Professor | Ling Yuan | Asia Growth Partners

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Name	Ling Yuan
Contact Information	yuanling@sklmg.edu.cn
Language ability	Chinese, English
Province	Hunan

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Name

Ling Yuan

Contact Information

yuanling@sklmg.edu.cn

Language ability

Chinese, English

Province

Hunan

University/Lab Affiliation and Title	Central South University
Faculty	Life Sciences
Academic Background & Achievements	2012-2018 PhD: Genetics and Developmental Biology, Chinese Academy of Sciences. Supervisor: Zhiheng Xu Research on neurodevelopment and related disease mechanisms Published as lead and corresponding author in top journals
Awards	2017: Selected achievements in 'China's Major Scientific and Technological Engineering Progress' 2017: Nominated for 'Top 30 Scientific Advances in China'

University/Lab Affiliation and Title

Central South University

Faculty

Life Sciences

Academic Background & Achievements

2012-2018 PhD: Genetics and Developmental Biology, Chinese Academy of Sciences. Supervisor: Zhiheng Xu
Research on neurodevelopment and related disease mechanisms
Published as lead and corresponding author in top journals

Awards

2017: Selected achievements in 'China's Major Scientific and Technological Engineering Progress'
2017: Nominated for 'Top 30 Scientific Advances in China'

Areas of Focus	Autism Spectrum Disorders
Publications	KCTD10 regulates brain development by destabilizing brain disorder-associated protein KCTD13, Ling Yuan, 2024 A Single Mutation in the prM Protein of Zika Virus Contributes to Fetal Microcephaly, Ling Yuan, 2017 MEKK3 Coordinates with FBW7 to Regulate WDR62 Stability and Neurogenesis, Ling Yuan, 2018 American Strain of Zika Virus Causes More Severe Microcephaly Than an Old Asian Strain in Neonatal Mice, Ling Yuan, 2017 Comparative Profiling of Gene Expression in Camellia Sinensis L. Cultivar AnJiBaiCha Leaves during Periodic Albinism, Ling Yuan, 2015 Epigenetic Regulation of Atrophin1 by Lysine-specific Demethylase 1 is Required for Cortical Progenitor Maintenance, Ling Yuan, 2014 Zika Virus Protease Cleavage of Host Protein Septin-2 Mediates Mitotic Defects in Neural Progenitors, Ling Yuan, 2019 Chloroquine, a FDA-approved Drug, Prevents Zika Virus Infection and its Associated Congenital Microcephaly in Mice, Ling Yuan, 2017 Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins, Ling Yuan, 2017 Fast Super-resolution Imaging Technique and Immediate Early Nanostructure Capturing by a Photo-convertible Fluorescent Protein, Ling Yuan, 2019 Pathophysiological Significance of WDR62 and JNK Signaling in Human Diseases, Ling Yuan, 2021 Zika Virus and Its Association with Neurological Disorders, Ling Yuan, 2022 Stress‑Activated Protein Kinase JNK Modulates Depression‑like Behaviors in Mice, Ling Yuan, 2023 GIGYF1 disruption associates with autism and impaired IGF-1R signaling, Ling Yuan, 2022 De novo variants in genes regulating stress granule assembly associate with neurodevelopmental disorders, Ling Yuan, 2022

Areas of Focus

Autism Spectrum Disorders

Publications

KCTD10 regulates brain development by destabilizing brain disorder-associated protein KCTD13, Ling Yuan, 2024
A Single Mutation in the prM Protein of Zika Virus Contributes to Fetal Microcephaly, Ling Yuan, 2017
MEKK3 Coordinates with FBW7 to Regulate WDR62 Stability and Neurogenesis, Ling Yuan, 2018
American Strain of Zika Virus Causes More Severe Microcephaly Than an Old Asian Strain in Neonatal Mice, Ling Yuan, 2017
Comparative Profiling of Gene Expression in Camellia Sinensis L. Cultivar AnJiBaiCha Leaves during Periodic Albinism, Ling Yuan, 2015
Epigenetic Regulation of Atrophin1 by Lysine-specific Demethylase 1 is Required for Cortical Progenitor Maintenance, Ling Yuan, 2014
Zika Virus Protease Cleavage of Host Protein Septin-2 Mediates Mitotic Defects in Neural Progenitors, Ling Yuan, 2019
Chloroquine, a FDA-approved Drug, Prevents Zika Virus Infection and its Associated Congenital Microcephaly in Mice, Ling Yuan, 2017
Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins, Ling Yuan, 2017
Fast Super-resolution Imaging Technique and Immediate Early Nanostructure Capturing by a Photo-convertible Fluorescent Protein, Ling Yuan, 2019
Pathophysiological Significance of WDR62 and JNK Signaling in Human Diseases, Ling Yuan, 2021
Zika Virus and Its Association with Neurological Disorders, Ling Yuan, 2022
Stress‑Activated Protein Kinase JNK Modulates Depression‑like Behaviors in Mice, Ling Yuan, 2023
GIGYF1 disruption associates with autism and impaired IGF-1R signaling, Ling Yuan, 2022
De novo variants in genes regulating stress granule assembly associate with neurodevelopmental disorders, Ling Yuan, 2022

Autism Neurodevelopment Genetics Gene Function Neuronal Activity Behavioral Analysis Multidisciplinary Disease Mechanisms Therapeutic Strategies Mouse Models

Yuan Xiaobing - East China Normal University

Hui Guo - Central South University

Xia Kun - Central South University

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