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Ling Yuan
Life Science
Central South University
Hunan
Language: Chinese, English
Autism
Neurodevelopment
Genetics
Gene Function
Neuronal Activity
Behavioral Analysis
Multidisciplinary
Disease Mechanisms
Therapeutic Strategies
Mouse Models
Areas of Focus
- Autism Spectrum Disorders
Academic Background & Achievements
- 2012-2018 PhD: Genetics and Developmental Biology, Chinese Academy of Sciences. Supervisor: Zhiheng Xu
- Research on neurodevelopment and related disease mechanisms
- Published as lead and corresponding author in top journals
Publications
- KCTD10 regulates brain development by destabilizing brain disorder-associated protein KCTD13, Ling Yuan, 2024
- A Single Mutation in the prM Protein of Zika Virus Contributes to Fetal Microcephaly, Ling Yuan, 2017
- MEKK3 Coordinates with FBW7 to Regulate WDR62 Stability and Neurogenesis, Ling Yuan, 2018
- American Strain of Zika Virus Causes More Severe Microcephaly Than an Old Asian Strain in Neonatal Mice, Ling Yuan, 2017
- Comparative Profiling of Gene Expression in Camellia Sinensis L. Cultivar AnJiBaiCha Leaves during Periodic Albinism, Ling Yuan, 2015
- Epigenetic Regulation of Atrophin1 by Lysine-specific Demethylase 1 is Required for Cortical Progenitor Maintenance, Ling Yuan, 2014
- Zika Virus Protease Cleavage of Host Protein Septin-2 Mediates Mitotic Defects in Neural Progenitors, Ling Yuan, 2019
- Chloroquine, a FDA-approved Drug, Prevents Zika Virus Infection and its Associated Congenital Microcephaly in Mice, Ling Yuan, 2017
- Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins, Ling Yuan, 2017
- Fast Super-resolution Imaging Technique and Immediate Early Nanostructure Capturing by a Photo-convertible Fluorescent Protein, Ling Yuan, 2019
- Pathophysiological Significance of WDR62 and JNK Signaling in Human Diseases, Ling Yuan, 2021
- Zika Virus and Its Association with Neurological Disorders, Ling Yuan, 2022
- Stress‑Activated Protein Kinase JNK Modulates Depression‑like Behaviors in Mice, Ling Yuan, 2023
- GIGYF1 disruption associates with autism and impaired IGF-1R signaling, Ling Yuan, 2022
- De novo variants in genes regulating stress granule assembly associate with neurodevelopmental disorders, Ling Yuan, 2022
Awards
- 2017: Selected achievements in 'China's Major Scientific and Technological Engineering Progress'
- 2017: Nominated for 'Top 30 Scientific Advances in China'
