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Shubing Zhang
Life Science
Central South University
Hunan
Language: Chinese, English
Cancer
Cell Signaling
Tumor Mechanisms
Drug Resistance
Natural Drugs
Pharmacology
Notch Signaling
Breast Cancer
Pancreatic Cancer
Prostate Cancer
Areas of Focus
- Oncology Biology
- Natural Medicinal Active Components and Pharmacodynamics
Work Experience
- 2002.9-2004.3 - Albert Einstein College of Medicine, Department of Molecular Pharmacology - Postdoctoral Researcher
- 2004.4-2005.6 - Zhejiang Yangshengtang Natural Medicine Research Institute - Department Head
- 2005.6-present - Central South University, School of Life Sciences, Department of Cell Biology - Associate Professor, Professor
- 2012.3-2014.8 - University of Mississippi Medical Center, Cancer Institute - Visiting Scholar
Academic Background & Achievements
- 1993.9-1997.7 Bachelor: Jilin University, Biochemistry
- 1997.9-2002.7 PhD: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
Publications
- Notch signaling via regulation of RB and p-AKT but not PIK3CG contributes to MIA PaCa-2 cell growth and migration to affect pancreatic carcinogenesis, Zhang S, Liu J, Xu K, Li Z, 2018
- Lunatic Fringe and p53 Cooperatively Suppress Mesenchymal Stem-Like Breast Cancer, Chung WC, Zhang S, Challagundla L, Zhou Y, Xu K, 2017
- Active Components of Fungus Shiraia bambusiscola Can Specifically Induce BGC823 Gastric Cancer Cell Apoptosis, Shubing Zhang, Dewen Qiu, Jingjiang Liu, Zhijian Li, 2016
- Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer, Zhang S, Chung WC, Xu K, 2016
- Manic Fringe Promotes a Claudin-Low Breast Cancer Phenotype through Notch-Mediated PIK3CG Induction, Zhang S, Chung WC, Wu G, Egan SE, Miele L, Xu K, 2015
- Tumor-suppressive activity of Lunatic Fringe in prostate through differential modulation of Notch receptor activation, Zhang S, Chung WC, Wu G, Egan SE, Xu K, 2014
- Targeting Met and Notch in the Lfng-deficient, Met-amplified triple-negative breast cancer, Zhang S, Loch AJ, Radtke F, Egan SE, Xu K, 2014
- Jagged1 is the major regulator of Notch-dependent cell fate in proximal airways, Zhang S, Loch AJ, Radtke F, Egan SE, Xu K, 2013
- 真菌竹黄双向调节TNF-α诱导的L929细胞凋亡过程, 张树冰, 周亚玲, 李凌, 李杰, 2012
- Loss of Reduced Folate Carrier Function and Folate Depletion Result in Enhanced Pemetrexed Inhibition of Purine Synthesis, Rongbao Zhao, Shubing Zhang, Marie Hanscom, Shrikanta Chattopadhyay, I. David Goldman, 2005
- The in vitro reconstitution of nucleosome and its binding patterns with HMG1/2 and HMG 14/17, Shubing Zhang, Jian huang, Hui Zhao, Yi Zhang, Chunhui Hou, Xiaodong Cheng, Chu Jiang, Minqian Li, Jun Hu, Ruolan Qian, 2003
- The interaction between the human beta-globin locus control region and nuclear matrix, Zhang Shubing, Qian Ruolan, 2002
- Function of GATA transcription factors in hydroxyurea-induced HEL cells, Zhang Shubing, Qiye He, Hui Zhao, Changyun Gui, Chu jiang, Ruolan Qian, 2001
- Interactions between GATA transcription factors and the DNaseI hypersensitive sites in the human beta-globin gene LCR, Zhang Shubing, Zhao Hui, Jiang Chu, et al., 2000
Awards
- Teaching Quality Excellence Award (2007-2008)
- Outstanding Class Advisor (2009-2011)
