Professor | Shubing Zhang | Asia Growth Partners

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Name	Shubing Zhang
Contact Information	shubingzhang@csu.edu.cn
Language ability	Chinese, English
Province	Hunan

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Name

Shubing Zhang

Contact Information

shubingzhang@csu.edu.cn

Language ability

Chinese, English

Province

Hunan

University/Lab Affiliation and Title	Central South University
Faculty	Life Sciences
Academic Background & Achievements	1993.9-1997.7 Bachelor: Jilin University, Biochemistry 1997.9-2002.7 PhD: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
Work Experience	2002.9-2004.3 - Albert Einstein College of Medicine, Department of Molecular Pharmacology - Postdoctoral Researcher 2004.4-2005.6 - Zhejiang Yangshengtang Natural Medicine Research Institute - Department Head 2005.6-present - Central South University, School of Life Sciences, Department of Cell Biology - Associate Professor, Professor 2012.3-2014.8 - University of Mississippi Medical Center, Cancer Institute - Visiting Scholar
Awards	Teaching Quality Excellence Award (2007-2008) Outstanding Class Advisor (2009-2011)

University/Lab Affiliation and Title

Central South University

Faculty

Life Sciences

Academic Background & Achievements

1993.9-1997.7 Bachelor: Jilin University, Biochemistry
1997.9-2002.7 PhD: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences

Work Experience

2002.9-2004.3 - Albert Einstein College of Medicine, Department of Molecular Pharmacology - Postdoctoral Researcher
2004.4-2005.6 - Zhejiang Yangshengtang Natural Medicine Research Institute - Department Head
2005.6-present - Central South University, School of Life Sciences, Department of Cell Biology - Associate Professor, Professor
2012.3-2014.8 - University of Mississippi Medical Center, Cancer Institute - Visiting Scholar

Awards

Teaching Quality Excellence Award (2007-2008)
Outstanding Class Advisor (2009-2011)

Areas of Focus	Oncology Biology Natural Medicinal Active Components and Pharmacodynamics
Publications	Notch signaling via regulation of RB and p-AKT but not PIK3CG contributes to MIA PaCa-2 cell growth and migration to affect pancreatic carcinogenesis, Zhang S, Liu J, Xu K, Li Z, 2018 Lunatic Fringe and p53 Cooperatively Suppress Mesenchymal Stem-Like Breast Cancer, Chung WC, Zhang S, Challagundla L, Zhou Y, Xu K, 2017 Active Components of Fungus Shiraia bambusiscola Can Specifically Induce BGC823 Gastric Cancer Cell Apoptosis, Shubing Zhang, Dewen Qiu, Jingjiang Liu, Zhijian Li, 2016 Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer, Zhang S, Chung WC, Xu K, 2016 Manic Fringe Promotes a Claudin-Low Breast Cancer Phenotype through Notch-Mediated PIK3CG Induction, Zhang S, Chung WC, Wu G, Egan SE, Miele L, Xu K, 2015 Tumor-suppressive activity of Lunatic Fringe in prostate through differential modulation of Notch receptor activation, Zhang S, Chung WC, Wu G, Egan SE, Xu K, 2014 Targeting Met and Notch in the Lfng-deficient, Met-amplified triple-negative breast cancer, Zhang S, Loch AJ, Radtke F, Egan SE, Xu K, 2014 Jagged1 is the major regulator of Notch-dependent cell fate in proximal airways, Zhang S, Loch AJ, Radtke F, Egan SE, Xu K, 2013 真菌竹黄双向调节TNF-α诱导的L929细胞凋亡过程, 张树冰, 周亚玲, 李凌, 李杰, 2012 Loss of Reduced Folate Carrier Function and Folate Depletion Result in Enhanced Pemetrexed Inhibition of Purine Synthesis, Rongbao Zhao, Shubing Zhang, Marie Hanscom, Shrikanta Chattopadhyay, I. David Goldman, 2005 The in vitro reconstitution of nucleosome and its binding patterns with HMG1/2 and HMG 14/17, Shubing Zhang, Jian huang, Hui Zhao, Yi Zhang, Chunhui Hou, Xiaodong Cheng, Chu Jiang, Minqian Li, Jun Hu, Ruolan Qian, 2003 The interaction between the human beta-globin locus control region and nuclear matrix, Zhang Shubing, Qian Ruolan, 2002 Function of GATA transcription factors in hydroxyurea-induced HEL cells, Zhang Shubing, Qiye He, Hui Zhao, Changyun Gui, Chu jiang, Ruolan Qian, 2001 Interactions between GATA transcription factors and the DNaseI hypersensitive sites in the human beta-globin gene LCR, Zhang Shubing, Zhao Hui, Jiang Chu, et al., 2000

Areas of Focus

Oncology Biology
Natural Medicinal Active Components and Pharmacodynamics

Publications

Notch signaling via regulation of RB and p-AKT but not PIK3CG contributes to MIA PaCa-2 cell growth and migration to affect pancreatic carcinogenesis, Zhang S, Liu J, Xu K, Li Z, 2018
Lunatic Fringe and p53 Cooperatively Suppress Mesenchymal Stem-Like Breast Cancer, Chung WC, Zhang S, Challagundla L, Zhou Y, Xu K, 2017
Active Components of Fungus Shiraia bambusiscola Can Specifically Induce BGC823 Gastric Cancer Cell Apoptosis, Shubing Zhang, Dewen Qiu, Jingjiang Liu, Zhijian Li, 2016
Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer, Zhang S, Chung WC, Xu K, 2016
Manic Fringe Promotes a Claudin-Low Breast Cancer Phenotype through Notch-Mediated PIK3CG Induction, Zhang S, Chung WC, Wu G, Egan SE, Miele L, Xu K, 2015
Tumor-suppressive activity of Lunatic Fringe in prostate through differential modulation of Notch receptor activation, Zhang S, Chung WC, Wu G, Egan SE, Xu K, 2014
Targeting Met and Notch in the Lfng-deficient, Met-amplified triple-negative breast cancer, Zhang S, Loch AJ, Radtke F, Egan SE, Xu K, 2014
Jagged1 is the major regulator of Notch-dependent cell fate in proximal airways, Zhang S, Loch AJ, Radtke F, Egan SE, Xu K, 2013
真菌竹黄双向调节TNF-α诱导的L929细胞凋亡过程, 张树冰, 周亚玲, 李凌, 李杰, 2012
Loss of Reduced Folate Carrier Function and Folate Depletion Result in Enhanced Pemetrexed Inhibition of Purine Synthesis, Rongbao Zhao, Shubing Zhang, Marie Hanscom, Shrikanta Chattopadhyay, I. David Goldman, 2005
The in vitro reconstitution of nucleosome and its binding patterns with HMG1/2 and HMG 14/17, Shubing Zhang, Jian huang, Hui Zhao, Yi Zhang, Chunhui Hou, Xiaodong Cheng, Chu Jiang, Minqian Li, Jun Hu, Ruolan Qian, 2003
The interaction between the human beta-globin locus control region and nuclear matrix, Zhang Shubing, Qian Ruolan, 2002
Function of GATA transcription factors in hydroxyurea-induced HEL cells, Zhang Shubing, Qiye He, Hui Zhao, Changyun Gui, Chu jiang, Ruolan Qian, 2001
Interactions between GATA transcription factors and the DNaseI hypersensitive sites in the human beta-globin gene LCR, Zhang Shubing, Zhao Hui, Jiang Chu, et al., 2000

Cancer Cell Signaling Tumor Mechanisms Drug Resistance Natural Drugs Pharmacology Notch Signaling Breast Cancer Pancreatic Cancer Prostate Cancer

Zhaojun Zeng - Central South University

Shubing Zhang - Central South University

Renqing Feng - Peking University

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