Professor | Cheng Shiya | Asia Growth Partners

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Name	Cheng Shiya
Contact Information	chengshiya@126.com
Language ability	Chinese, English
Province	Hubei

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Name

Cheng Shiya

Contact Information

chengshiya@126.com

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Medical School
Academic Background & Achievements	2005-2009 Bachelor: Sichuan University, School of Life Sciences 2009-2014 PhD: Peking Union Medical College/Beijing Institute of Life Sciences, Biochemistry and Molecular Biology
Work Experience	2014-2016 - Beijing Institute of Life Sciences - Postdoctoral Researcher 2016-2024 - Max Planck Institute for Multidisciplinary Sciences - Postdoctoral Researcher 2024-Present - Wuhan University, Taikang Medical College (Basic Medical College) - Professor 2024-Present - Wuhan University, Taikang Life Medical Center - PI
Awards	National Talent Project (2023) Hubei Province Talent Project (2023) EMBO Long-Term Fellowship (2016)

University/Lab Affiliation and Title

Wuhan University

Faculty

Medical School

Academic Background & Achievements

2005-2009 Bachelor: Sichuan University, School of Life Sciences
2009-2014 PhD: Peking Union Medical College/Beijing Institute of Life Sciences, Biochemistry and Molecular Biology

Work Experience

2014-2016 - Beijing Institute of Life Sciences - Postdoctoral Researcher
2016-2024 - Max Planck Institute for Multidisciplinary Sciences - Postdoctoral Researcher
2024-Present - Wuhan University, Taikang Medical College (Basic Medical College) - Professor
2024-Present - Wuhan University, Taikang Life Medical Center - PI

Awards

National Talent Project (2023)
Hubei Province Talent Project (2023)
EMBO Long-Term Fellowship (2016)

Areas of Focus	Oogenesis and early embryonic development
Publications	Translational control of prophase I arrest in mouse oocytes, Cheng, S. and Schuh, M., 2024 Mammalian oocytes store mRNAs in a mitochondria-associated membraneless compartment, Cheng, S., Altmeppen, G., So, C., Welp, L.M., Penir, S., Ruhwedel, T., Menelaou, K., Harasimov, K., Stützer, A., Blayney, M., Elder, K., Möbius, W., Urlaub, H., and Schuh, M., 2022 Mouse oocytes sequester aggregated proteins in degradative super-organelles, Zaffagnini, G., Cheng, S., Salzer, M.C., Pernaute, B., Duran, J.M., Irimia, M., Schuh, M., Böke, E., 2024 HIV-1 capsids enter the FG phase of nuclear pores like a transport receptor, Fu, L., Weiskopf, E.N., Akkermans, O., Swanson, N.A., Cheng, S., Schwartz, T.U., and Gorlich, D., 2024 The maintenance of oocytes in the mammalian ovary involves extreme protein longevity, Harasimov, K., Gorry, R.L., Welp, L.M., Penir, S., Horokhovskyi, Y., Cheng, S., Takaoka, K., Stützer, A., Frombach, A., Taylor-Tavares, A.L., Raabe, M., Haag, S., Saha, D., Grewe, K., Schipper, V., Rizzoli, S.O., Urlaub, H., Liepe, J., Schuh, M., 2024 Phase Separation during Germline Development, So, C., Cheng, S., and Schuh, M., 2021 Distinct roles of two myosins in C. elegans spermatid differentiation, Hu, J., Cheng, S., Wang, H., Li, X., Liu, S., Wu, M., Liu, Y., and Wang, X., 2019 Dissecting Phagocytic Removal of Apoptotic Cells in Caenorhabditis elegans, Cheng, S., Liu, K., Yang, C., and Wang, X., 2017 PtdIns(4,5)P2 and PtdIns3P coordinate to regulate phagosomal sealing for apoptotic cell clearance, Cheng, S., Wang, K., Zou, W., Miao, R., Huang, Y., Wang, H., and Wang, X., 2015 PI3P phosphatase activity is required for autophagosome maturation and autolysosome formation, Wu, Y., Cheng, S., Zhao, H., Zou, W., Yoshina, S., Mitani, S., Zhang, H., and Wang, X., 2014 Autophagy genes coordinate with the class II PI/PtdIns 3-kinase PIKI-1 to regulate apoptotic cell clearance in C. elegans, Cheng, S., Wu, Y., Lu, Q., Yan, J., Zhang, H., and Wang, X., 2013 Autophagy activity contributes to programmed cell death in Caenorhabditis elegans, Wang, H., Lu, Q., Cheng, S., Wang, X., and Zhang, H., 2013 Autophagy genes function sequentially to promote apoptotic cell corpse degradation in the engulfing cell, Li, W., Zou, W., Yang, Y., Chai, Y., Chen, B., Cheng, S., Tian, D., Wang, X., Vale, R.D., and Ou, G., 2012

Areas of Focus

Oogenesis and early embryonic development

Publications

Translational control of prophase I arrest in mouse oocytes, Cheng, S. and Schuh, M., 2024
Mammalian oocytes store mRNAs in a mitochondria-associated membraneless compartment, Cheng, S.*, Altmeppen, G.*, So, C., Welp, L.M., Penir, S., Ruhwedel, T., Menelaou, K., Harasimov, K., Stützer, A., Blayney, M., Elder, K., Möbius, W., Urlaub, H., and Schuh, M., 2022
Mouse oocytes sequester aggregated proteins in degradative super-organelles, Zaffagnini, G., Cheng, S., Salzer, M.C., Pernaute, B., Duran, J.M., Irimia, M., Schuh, M., Böke, E., 2024
HIV-1 capsids enter the FG phase of nuclear pores like a transport receptor, Fu, L., Weiskopf, E.N., Akkermans, O., Swanson, N.A., Cheng, S., Schwartz, T.U., and Gorlich, D., 2024
The maintenance of oocytes in the mammalian ovary involves extreme protein longevity, Harasimov, K., Gorry, R.L., Welp, L.M., Penir, S., Horokhovskyi, Y., Cheng, S., Takaoka, K., Stützer, A., Frombach, A., Taylor-Tavares, A.L., Raabe, M., Haag, S., Saha, D., Grewe, K., Schipper, V., Rizzoli, S.O., Urlaub, H., Liepe, J., Schuh, M., 2024
Phase Separation during Germline Development, So, C.*, Cheng, S.*, and Schuh, M., 2021
Distinct roles of two myosins in C. elegans spermatid differentiation, Hu, J.*, Cheng, S.*, Wang, H., Li, X., Liu, S., Wu, M., Liu, Y., and Wang, X., 2019
Dissecting Phagocytic Removal of Apoptotic Cells in Caenorhabditis elegans, Cheng, S., Liu, K., Yang, C., and Wang, X., 2017
PtdIns(4,5)P2 and PtdIns3P coordinate to regulate phagosomal sealing for apoptotic cell clearance, Cheng, S., Wang, K., Zou, W., Miao, R., Huang, Y., Wang, H., and Wang, X., 2015
PI3P phosphatase activity is required for autophagosome maturation and autolysosome formation, Wu, Y., Cheng, S., Zhao, H., Zou, W., Yoshina, S., Mitani, S., Zhang, H., and Wang, X., 2014
Autophagy genes coordinate with the class II PI/PtdIns 3-kinase PIKI-1 to regulate apoptotic cell clearance in C. elegans, Cheng, S., Wu, Y., Lu, Q., Yan, J., Zhang, H., and Wang, X., 2013
Autophagy activity contributes to programmed cell death in Caenorhabditis elegans, Wang, H., Lu, Q., Cheng, S., Wang, X., and Zhang, H., 2013
Autophagy genes function sequentially to promote apoptotic cell corpse degradation in the engulfing cell, Li, W., Zou, W., Yang, Y., Chai, Y., Chen, B., Cheng, S., Tian, D., Wang, X., Vale, R.D., and Ou, G., 2012

Oogenesis Embryonic Development Infertility Oocytes Maternal Factors Mrna Proteins Organelles Mechanisms Therapeutic Approaches

Yanwu Wang - Wuhan University

Shuliang Chen - Wuhan University

Wei Tuo - University of Chinese Academy of Sciences

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