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Xiao Chen
Medical School
Wuhan University
Hubei
Language: English, Chinese, German
Nanomaterials
Biological Organisms
Cellular Mechanisms
Human Diseases
Diagnosis
Treatment
Tumor Immune Microenvironment
Immunotherapy
Nanodrug Delivery
Tumor Treatment
Areas of Focus
- Exploration of the interactions between nanomaterials and biological organisms and their cellular molecular mechanisms
- Use of nanomaterials/drugs for the diagnosis and treatment of human diseases
- Regulation of the tumor immune microenvironment and immunotherapy for tumors using nanodrug delivery systems
Work Experience
- 2016.12 - 2017.05: Visiting Professor, Graduate School of Human and Environmental Studies, Kyoto University, Japan
- 2014.10 - Present: Professor, Department of Pharmacology, Basic Medical College, Wuhan University
- 2012.7 - 2014.7: JSPS Special Research Fellow, Dental School, Hokkaido University, Japan
- 2002.6 - 2012.6: Assistant/Instructor, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology
Academic Background & Achievements
- 2005-2010: PhD in Public Health, Tongji Medical College, Huazhong University of Science and Technology
- 2007-2009: DAAD Scholarship PhD Student, Medical School, University of Tübingen, Germany
- 1999-2002: Master's in Pharmacology, Wuhan University Medical School
- 1994-1999: Bachelor's in Clinical Medicine, Hubei Medical University
Publications
- Doxorubicin-polyglycerol-nanodiamond composites stimulate glioblastoma cell immunogenicity through activation of autophagy, X Chen et al., 2019
- Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates, X Chen et al., 2018
- Dendritic cell-mediated delivery of doxorubicin-polyglycerol-nanodiamond composites elicits enhanced anti-cancer immune response in glioblastoma, X Chen et al., 2018
- Harnessing the cross-talk between tumor cells and tumor-associated macrophages with a nano-drug for modulation of glioblastoma immune microenvironment, X Chen et al., 2017
- Monocyte-mediated chemotherapy drug delivery in glioblastoma, X Chen et al., 2018
- Suppression of c-Myc is involved in multi-walled carbon nanotubes' down-regulation of ATP-binding cassette transporters in human colon adenocarcinoma cells, X Chen et al., 2015
- Platinum on Nanodiamond: A Promising Prodrug Conjugated with Stealth Polyglycerol, Targeting peptide, and Acid-Responsive Antitumor Drug, X Chen et al., 2014
- Polyglycerol-coated nanodiamond as a macrophage-evading platform for selective drug delivery in cancer cells, X Chen et al., 2014
