Areas of Focus
- Drug targets and new drug development
- Exogenous substance developmental toxicology
Work Experience
- 2012.12 - 2022.8: Second-level Professor, Doctoral Supervisor, Director of Provincial Key Laboratory, Department of Pharmacology, Wuhan University
- 2000.4 - 2012.12: Professor, Doctoral Supervisor, Department Head, Vice Dean, Department of Pharmacology, Wuhan University
- 1997.1 - 2000.3: Associate Professor, Department of Pharmacology, Hubei Medical University
- 1993.6 - 1996.12: Lecturer, Department of Pharmacology, Hubei Medical University
- 1991.6 - 1993.5: Assistant, Department of Pharmacology, Hubei Medical University
- 1986.7 - 1988.8: Resident Physician, Third Hospital of Wuhan
Academic Background & Achievements
- 2004.4 - 2004.7: Studied at National Education Administration College
- 1996.9 - 1999.6: PhD in Hepatic Pharmacology, Hubei Medical University
- 1988.9 - 1991.7: Master's in Pharmacology, Hubei Medical University
- 1981.9 - 1986.7: Bachelor of Medicine, Hubei Medical College
Publications
- Metal-Drug Nanoparticles-Mediated Osteolytic Microenvironment Regulation for Enhanced Radiotherapy of Orthotopic Osteosarcoma, Geng H, Zhou MX, Li B, Liu L, Yang X, Wen YX, Yu HJ, Wang H*, Chen J*, Chen LB*, 2021
- Developmental toxicity and programming alterations of multiple organs in offspring induced by medication during pregnancy, Lu ZJ, Guo Y, Xu D, Xiao H, Kou H, Ao Y, Liu KX, Chen LB*, Wang H*, 2022
- Hyperglycemia-induced accumulation of advanced glycosylation end products in fibroblast-like synoviocytes promotes knee osteoarthritis, Li QX, Wen YX, Wang LL, Chen B, Chen J, Wang H*, Chen LB*, 2021
- P-gp expression inhibition mediates placental glucocorticoid barrier opening and fetal weight loss, Ge CY, Xu D, Yu PX, Fang M, Guo JJ, Xu D, Qiao Y, Chen SJ, Zhang YZ*, Wang H*, 2021
- Dexamethasone induces an imbalanced fetal-placental-maternal bile acid circulation: Involvement of placental transporters, Huang W, Zhou J, Guo JJ, Hu W, Chen GH, Li B, Wen YJ, Jiang YM, Fu KL, Bi HC*, Zhang YZ*, Wang H*, 2021
- Prenatal dexamethasone exposure induced pancreatic β-cell dysfunction and glucose intolerance of male offspring rats: Role of the epigenetic repression of ACE2, Dai Y, Kou H, Gui S, Guo X, Liu H, Gong Z, Sun X, Wang H*, Guo Y*, 2022
- Differential expression of placental 11β-HSD2 induced by high maternal glucocorticoid exposure mediates sex differences in placental and fetal development, Yu P, Zhou J, Ge C, Fang M, Zhang Y, Wang H*, 2022
- Maternally derived low glucocorticoid mediates adrenal developmental programming alteration in offspring induced by dexamethasone, Chen YW, Xia X, Fang M, Chen GH, Cao JG, Qu H, Wang H*, 2021
- H19/let-7 axis mediates caffeine exposure during pregnancy induced adrenal dysfunction and its multi-generation inheritance, He Z, Zhang JZ, Chen GH, Cao JG, Chen YW, Ai C, Wang H*, 2021
- Intrauterine endogenous high glucocorticoids program ovarian dysfunction in female offspring secondary to prenatal caffeine exposure, Lv F, Fan GL, Wan Y, Chen YX, Ni Y, Huang J, Xu D, Zhang W*, Wang H*, 2021
- 11β-Hydroxysteroid dehydrogenase 2: A key mediator of high susceptibility to osteoporosis in offspring after prenatal dexamethasone exposure, Wu Z, Wen Y, Xiao H, Zhu J, Li B, Shangguan Y, He H, Wang H*, Chen L*, 2022
- miRNA320a-3p/RUNX2 signal programming mediates the transgenerational inheritance of inhibited ovarian estrogen synthesis in female offspring rats induced by prenatal dexamethasone exposure, Gong XH, Zhang JZ, Ge CY, Yi YW, Dai SY, Fan GL, Zhang YZ, Wang H*, Xu D*, 2021
- Sex difference in adrenal developmental toxicity induced by dexamethasone and its intrauterine programming mechanism, Chen YW, Xu D, Xia X, Chen GH, Xiao H, Chen LB*, Wang H*, 2021
- Programming changes in GLUT1 mediated the accumulation of AGEs and matrix degradation in the articular cartilage of female adult rats after prenatal caffeine exposure, Li QX, Wang LL, Wang YZ, Liu L, Han H, Chen LB*, Wang H*, 2020
- The low-expression programming of 11β-HSD2 mediates osteoporosis susceptibility induced by prenatal caffeine exposure in male offspring rats, Xiao H, Wu ZX, Li B, Shangguan YF, Jean-François Stoltz, Jacques Magdalou, Chen LB *, Wang H*, 2020
Awards
- 2019: Second Hubei Medical Leadership Training Program and Head of Hubei Famous Medical Studio
- 2017: Distinguished Teaching Professor, Wuhan University
- 2016: Luojia Outstanding Scholar, Wuhan University (re-awarded)
- 2016: Special Allowance from the Hubei Provincial Government
- 2014: President's Award for Outstanding Contribution to Teaching, Wuhan University
- 2014: Zhu Yubi Medical Prize, Medical Department, Wuhan University
- 2013: Luojia Outstanding Scholar, Wuhan University
- 2013: Top Ten Moral Models in Teaching, Wuhan University
- 2012: 'Respect for Teachers and Love for Learning' - My Favorite Top Ten Excellent Teachers, Wuhan University
- 2005: Wuhan Science and Technology Rising Star
- 2001: Talent Special Allowance from Wuhan Municipal Government
- 2001: Baosteel Education Fund National Outstanding Teacher Award
- 2000: Servier National Young Pharmacologist Honor Title, Chinese Pharmacological Society
- 1999: Recognition for Scientific Innovation and Achievement Promotion in Higher Education, Hubei Province
- 1998: Third Prize in Young Teacher Category (Teaching), Huo Yingdong Education Foundation