Professor | Yang Jing | Asia Growth Partners

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Name	Yang Jing
Contact Information	yangjingliu2013@163.com
Language ability	Chinese, English
Province	Hubei

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Name

Yang Jing

Contact Information

yangjingliu2013@163.com

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Medical School
Academic Background & Achievements	1998-2001: PhD in Internal Medicine, Wuhan University 1987-1990: Master's in Pathogenic Biology, Hubei Medical University 1982-1987: Bachelor's in Clinical Medicine, Hubei Medical University Published nearly 30 SCI-indexed papers High Citation Award from Pharmacol Res journal in 2009
Work Experience	2007-present: Professor, Deputy Head of Department, Pharmacology Department, Basic Medical College, Wuhan University 2002-2006: Associate Professor, Deputy Head of Department, Pharmacology Department, Medical College, Wuhan University 2006: Research Training, Pharmacology Department, Fukushima Medical University, Japan 1990-1998: Physician, Senior Physician, Clinical Pharmacology Laboratory, Hubei Provincial Institute of Geriatric Medicine
Awards	2011: New Drug Certificate and Production Approval for 'Valtrate Extract and Spasmolysis Capsule' (Drug Approval Number: Z20110032) Major Scientific and Technological Achievement Award, Wuhan (WK200608010)

University/Lab Affiliation and Title

Wuhan University

Faculty

Medical School

Academic Background & Achievements

1998-2001: PhD in Internal Medicine, Wuhan University
1987-1990: Master's in Pathogenic Biology, Hubei Medical University
1982-1987: Bachelor's in Clinical Medicine, Hubei Medical University
Published nearly 30 SCI-indexed papers
High Citation Award from Pharmacol Res journal in 2009

Work Experience

2007-present: Professor, Deputy Head of Department, Pharmacology Department, Basic Medical College, Wuhan University
2002-2006: Associate Professor, Deputy Head of Department, Pharmacology Department, Medical College, Wuhan University
2006: Research Training, Pharmacology Department, Fukushima Medical University, Japan
1990-1998: Physician, Senior Physician, Clinical Pharmacology Laboratory, Hubei Provincial Institute of Geriatric Medicine

Awards

2011: New Drug Certificate and Production Approval for 'Valtrate Extract and Spasmolysis Capsule' (Drug Approval Number: Z20110032)
Major Scientific and Technological Achievement Award, Wuhan (WK200608010)

Areas of Focus	Functional studies of important lipid metabolites in cell membranes Innovative drug research and development
Publications	CYP4A in tumor-associated macrophages promotes pre-metastatic niche formation and metastasis, Yang J, 2017 Inhibition of CYP4A by a novel flavonoid FLA-16 prolongs survival and normalizes tumor vasculature in glioma, Yang J, 2017 20-HETE regulates the angiogenic functions of human endothelial progenitor cells and contributes to angiogenesis in vivo, Yang J, 2014 Isoliquiritigenin, a flavonoid from licorice, blocks M2 macrophage polarization in colitis-associated tumorigenesis through downregulating PGE2 and IL-6, Yang J, 2014 Downregulation of COX-2 and CYP 4A signaling by isoliquiritigenin inhibits human breast cancer metastasis through preventing anoikis resistance, migration and invasion, Yang J, 2014 Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer, Yang J, 2013 Increased expression of CYP4Z1 promotes tumor angiogenesis and growth in human breast cancer, Yang J, 2012 Antitumor and immunostimulatory activity of a polysaccharide–protein complex from Scolopendra subspinipes mutilans L. Koch in tumor-bearing mice, Yang J, 2012 Cytochrome P450 ω-hydroxylase promotes angiogenesis and metastasis by upregulation of VEGF and MMP-9 in non-small cell lung cancer, Yang J, 2011 Protective effects of isoliquiritigenin in transient middle cerebral artery occlusion-induced focal cerebral ischemia in rats, Yang J, 2006

Areas of Focus

Functional studies of important lipid metabolites in cell membranes
Innovative drug research and development

Publications

CYP4A in tumor-associated macrophages promotes pre-metastatic niche formation and metastasis, Yang J*, 2017
Inhibition of CYP4A by a novel flavonoid FLA-16 prolongs survival and normalizes tumor vasculature in glioma, Yang J*, 2017
20-HETE regulates the angiogenic functions of human endothelial progenitor cells and contributes to angiogenesis in vivo, Yang J*, 2014
Isoliquiritigenin, a flavonoid from licorice, blocks M2 macrophage polarization in colitis-associated tumorigenesis through downregulating PGE2 and IL-6, Yang J*, 2014
Downregulation of COX-2 and CYP 4A signaling by isoliquiritigenin inhibits human breast cancer metastasis through preventing anoikis resistance, migration and invasion, Yang J*, 2014
Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer, Yang J*, 2013
Increased expression of CYP4Z1 promotes tumor angiogenesis and growth in human breast cancer, Yang J*, 2012
Antitumor and immunostimulatory activity of a polysaccharide–protein complex from Scolopendra subspinipes mutilans L. Koch in tumor-bearing mice, Yang J*, 2012
Cytochrome P450 ω-hydroxylase promotes angiogenesis and metastasis by upregulation of VEGF and MMP-9 in non-small cell lung cancer, Yang J*, 2011
Protective effects of isoliquiritigenin in transient middle cerebral artery occlusion-induced focal cerebral ischemia in rats, Yang J*, 2006

Lipid Metabolism Cell Membrane Cancer Angiogenesis Metastasis Arachidonic Acid Cox Lox Cyp Enzymes Biological Activity

Yi Lu - Southern University of Science and Technology

An Ping - Wuhan University

Jialing Liu - Southern University of Science and Technology

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