CDK12 and Integrator-PP2A Complex Modulates LEO1 Phosphorylation for Processive Transcription Elongation, Qiu M., Yin Z., Wang H., Lei L., Li C., Cui Y., Dai R., Yang P., Xiang Y., Li Q., Lv J., Hu Z., Chen M., Zhou H., Fang, P.*, Xiao R.*, Liang K.*, 2023
The super elongation complex drives transcriptional addiction in MYCN-amplified neuroblastoma, Wang D., Yin Z., Wang H., Wang L., Li T., Xiao R., Xie T., Han R., Dong R., Liu H.*, Liang K.*, Qing G.*, 2023
G-quadruplexes sense natural porphyrin metabolites for regulation of gene transcription and chromatin landscapes, Li C., Yin Z., Xiao R., Huang B., Cui Y., Wang H., Xiang Y., Wang L., Lei L., Ye J., Li T., Zhong Y., Guo F., Xia Y., Fang P. *, Liang K.*, 2022
Genome-Wide Native R-Loop Profiling by R-Loop Cleavage Under Targets and Tagmentation (R-Loop CUT&Tag), H. Wang, C. Li, K. Liang*, 2022
PCGF6 controls neuroectoderm specification of human pluripotent stem cells by activating SOX2 expression, X. Lan, S. Ding, T. Zhang, Y. Yi, C. Li, W. Jin, J. Chen, K. Liang, H. Wang, W. Jiang, 2022
Ligand-induced Native G-quadruplexes Stabilization Impairs Transcription Initiation, C. Li#, H. Wang#, Z. Yin#, P. Fang#, R. Xiao, Y. Xiang, W. Wang, Q. Li, B. Huang, J. Huang, K. Liang*, 2021
Genomic Profiling of Native R-loops with a DNA-RNA Hybrid Recognition Sensor, K. Wang, H. Wang, C. Li, Z. Yin, R. Xiao, Q. Li, Y. Xiang, W. Wang, J. Huang, L. Chen, P. Fang*, K. Liang*, 2021
Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase, Zheng. H., Qi. Y., Hu. S., Cao. X., Xu. C., Yin. Z., Chen. X., Li. Y., Liu. W., Li. J., Wang. J., Wei, G., Liang, K., Chen. F., and Xu. Y., 2020
DOT1L-controlled cell-fate determination and transcription elongation are independent of H3K79 methylation, Cao, K., Ugarenko, M., Ozark, P.A., Wang, J., Marshall, S.A., Rendleman, E.J., Liang, K., Wang, L., Zou, L., Smith, E.R., et al., 2020
Targeting Processive Transcription Elongation Via SEC Disruption For MYC-induced Cancer Therapy, K. Liang, E. R. Smith, Y. Aoi, K. L. Stoltz, H. Katagi, A. R. Woodfin, E. J. Rendleman, S. A. Marshall, D. C. Murray, L.Wang, P. A. Ozark, R.K. Mishra, R. Hashizume, G. E. Schiltz, and A. Shilatifard, 2018
A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemic Pathogenesis, A. Volk, K. Liang, J. Zhao, X. Li, M.Bulic, S. Marshall, J.W. Taub, Y. Ge, S. Malinge, E. Bartom, A. Shilatifard, and J.D Crispino, 2018
Therapeutic Targeting of Mll Degradation Pathways in Mll-Rearranged Leukemia, K. Liang, A. G. Volk, J. S. Haug, S. A. Marshall, A. R. Woodfin, E. T. Bartom, J. M. Gilmore, L. Florens, M. P. Washburn, K. D. Sullivan, J. M. Espinosa, J. Cannova, J. Zhang, E. R. Smith, J. D. Crispino, and A. Shilatifard, 2017
A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism, Wang, L., Collings, C.K., Zhao, Z., Cozzolino, K.A., Ma, Q., Liang, K., Marshall, S.A., Sze, C.C., Hashizume, R., Savas, J.N., et al., 2017
Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications, Ebmeier, C.C., Erickson, B., Allen, B.L., Allen, M.A., Kim, H., Fong, N., Jacobsen, J.R., Liang, K., Shilatifard, A., Dowell, R.D., et al., 2017
Mitotic Transcriptional Activation: Clearance of Actively Engaged Pol Ii Via Transcriptional Elongation Control in Mitosis, K. Liang, A. R. Woodfin, B. D. Slaughter, J. R. Unruh, A. C. Box, R. A. Rickels, X. Gao, J. S. Haug, S. L. Jaspersen, and A. Shilatifard, 2015
Characterization of Human Cyclin-Dependent Kinase 12 (Cdk12) and Cdk13 Complexes in C-Terminal Domain Phosphorylation, Gene Transcription, and Rna Processing, K. Liang, X. Gao, J. M. Gilmore, L. Florens, M. P. Washburn, E. Smith, and A. Shilatifard, 2015
Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4, Herz, H.M., Mohan, M., Garruss, A.S., Liang, K., Takahashi, Y.H., Mickey, K., Voets, O., Verrijzer, C.P., and Shilatifard, A., 2012
Estrogen Stimulates Degradation of Beta-Amyloid Peptide by up-Regulating Neprilysin, K. Liang#, L. Yang#, C. Yin, Z. Xiao, J. Zhang, Y. Liu, and J. Huang, 2010
