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Dongcheng Wu
Medical School
Wuhan University
Hubei
Language: English, Chinese
Diabetic Nephropathy
Molecular Mechanisms
Prevention
Stem Cells
Drug Development
Knee Osteoarthritis
Premature Ovarian Failure
Acute Lung Injury
Clinical Research
Intractable Diseases
Areas of Focus
- Pathological molecular mechanisms and prevention of diabetic nephropathy
- Research and development of new drugs from stem cells, focusing on treatment of intractable diseases such as diabetic nephropathy, knee osteoarthritis, premature ovarian failure, and acute lung injury
Work Experience
- 2009-present: Professor, Basic Medical College, Wuhan University
- 2012-present: Chairman, General Manager, Chief Scientist, Wuhan Hamilton Biotechnology Co., Ltd.
- 2014-2015: Dean, College of Chemistry and Life Sciences, Hubei Second Normal University
- 2007-2009: Research Scientist, McMaster University, Canada
- 2005-2007: Postdoctoral Fellow, McMaster University, Canada
- 2001-2005: Visiting Scholar, McMaster University, Canada
- 1993-1998: Lecturer, Basic Medical College, Hubei Medical University
Academic Background & Achievements
- 2002-2005: PhD in Clinical Laboratory Science, Wuhan University
- 1998-2000: Master's in Biochemistry, Hong Kong University of Science and Technology
- 1990-1993: Master's in Biochemistry, Hubei Medical University
- 1982-1987: Bachelor's in Clinical Medicine, Hubei Medical College
Publications
- Intra-articular injection of human umbilical cord mesenchymal stem cells ameliorates monosodium iodoacetate-induced osteoarthritis in rats by inhibiting cartilage degradation and inflammation, Zhang Q, Xiang E, Rao W, Zhang YQ, Xiao CH, Li CY, Han B, Wu DC*, 2021
- Human umbilical cord-derived mesenchymal stem cells prevent the progression of early diabetic nephropathy through inhibiting inflammation and fibrosis, Xiang E, Han B, Zhang Q, Rao W, Wang ZF, Chang C, Zhang YQ, Tu CS, Li CY, Wu DC*, 2020
- Umbilical Cord-Derived Mesenchymal Stem Cells Ameliorate Nephrocyte Injury and Proteinuria in a Diabetic Nephropathy Rat Model, Chen L, Xiang E, Li CY*, Han B, Zhang Q, Rao W, Xiao CH, Wu DC*, 2020
- Intrauterine transplantation of autologous menstrual blood stem cells increases endometrial thickness and pregnancy potential in patients with refractory intrauterine adhesion, Ma HN, Liu MT, Li YF, Wang W, Yang KQ, Lu LY, He M, Deng TR , Li ML, Wu DC*, 2020
- ABIN1 inhibits HDAC1 ubiquitination and protects it from both proteasome- and lysozyme-dependent degradation, Ma Y, Yuan S, Tian X, Lin S, Wei S, Hu T, Chen S, Li X, Chen S, Wu DC*, Wang M, Guo D, 2018
- Retinoids Regulate Adipogenesis Involving the TGFβ/SMAD and Wnt/β-Catenin Pathways in Human Bone Marrow Mesenchymal Stem Cells, Cao J, Ma Y, Yao W, Zhang X, Wu DC*, 2017
- Alterations in expression levels of genes in p53-related pathways determined using RNA-Seq analysis in patients with breast cancer following CIK therapy, Hu Z, Zhang X, Yang H, Qin S, Liu Y, Xiong W, Yuan B, Li L, Yao W, Wu DC*, 2017
Awards
- 2020: Selected for the 10th Batch of Hubei Province Hundred Talents Plan
- 2020: Leader of the Entrepreneurial Leading Team Project of Zengcheng District, Guangzhou
- 2016: Innovation and Entrepreneurship Mentor, Basic Medical College, Wuhan University
- 2012: Selected for the 5th Batch of '3551 Optical Valley Talent Plan', Wuhan
- 2009: Chutian Scholar Distinguished Professor, Hubei Province
- 2008: Postdoctoral Research Award, Canadian Society of Nephrology
- 2003: Third Prize, Hubei Province Natural Science Award
