Professor | Pingping Fang | Asia Growth Partners

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Name	Pingping Fang
Contact Information	pingpingfang@whu.edu.cn
Language ability	English, Chinese
Province	Hubei

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Name

Pingping Fang

Contact Information

pingpingfang@whu.edu.cn

Language ability

English, Chinese

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Medical School
Academic Background & Achievements	2013.08-2018.05 PhD in Pharmacology, University of Kansas Medical Center, USA 2008.09-2010.06 Master in Biochemistry and Molecular Biology, Wuhan University, China 2004.09-2008.06 Bachelor in Biotechnology, Weifang University, China
Work Experience	2020.01-present Distinguished Associate Researcher, Department of Pharmacology, School of Basic Medical Sciences, Wuhan University 2018.07-2018.12 Postdoctoral Fellow, Comprehensive Cancer Center, University of New Mexico, USA 2017.08-2018.06 Visiting Scholar, Comprehensive Cancer Center, University of New Mexico, USA 2013.08-2017.08 Teaching and Research Assistant, University of Kansas Medical Center, USA 2011.11-2013.08 Laboratory Technician, Stowers Institute for Medical Research, USA 2010.07-2011.06 Research Assistant, College of Life Sciences, Wuhan University, China

University/Lab Affiliation and Title

Wuhan University

Faculty

Medical School

Academic Background & Achievements

2013.08-2018.05 PhD in Pharmacology, University of Kansas Medical Center, USA
2008.09-2010.06 Master in Biochemistry and Molecular Biology, Wuhan University, China
2004.09-2008.06 Bachelor in Biotechnology, Weifang University, China

Work Experience

2020.01-present Distinguished Associate Researcher, Department of Pharmacology, School of Basic Medical Sciences, Wuhan University
2018.07-2018.12 Postdoctoral Fellow, Comprehensive Cancer Center, University of New Mexico, USA
2017.08-2018.06 Visiting Scholar, Comprehensive Cancer Center, University of New Mexico, USA
2013.08-2017.08 Teaching and Research Assistant, University of Kansas Medical Center, USA
2011.11-2013.08 Laboratory Technician, Stowers Institute for Medical Research, USA
2010.07-2011.06 Research Assistant, College of Life Sciences, Wuhan University, China

Areas of Focus	Development of genomic and proteomic research methods Study of drug resistance in targeted therapies and exploration of new targeted treatment strategies
Publications	CDK12 and Integrator-PP2A Complex Modulates LEO1 Phosphorylation for Processive Transcription Elongation, Qiu M., Yin Z., Wang H., Lei L., Li C., Cui Y., Dai R., Yang P., Xiang Y., Li Q., Lv J., Hu Z., Chen M., Zhou H., Fang, P., Xiao R., Liang K., 2023 G-quadruplexes sense natural porphyrin metabolites for regulation of gene transcription and chromatin landscapes, Li C., Yin Z., Xiao R., Huang B., Cui Y., Wang H., Xiang Y., Wang L., Lei L., Ye J., Li T., Zhong Y., Guo F., Xia Y., Fang P., Liang K., 2022 Discovery of Novel Bicyclic Phenylselenyl-Containing Hybrids: An Orally Bioavailable, Potential, and Multiacting Class of Estrogen Receptor Modulators against Endocrine-Resistant Breast Cancer, X. Deng, B. Xie, Q. Li, Y. Xiao, Z. Hu, X. Deng, P. Fang, C. Dong, H. Zhou, J. Huang, 2022 Ligand-induced Native G-quadruplexes Stabilization Impairs Transcription Initiation, C. Li, H. Wang, Z. Yin, P. Fang, R. Xiao, Y. Xiang, W. Wang, Q. Li, B. Huang, J. Huang, K. Liang, 2021 Genomic Profiling of Native R-loops with a DNA-RNA Hybrid Recognition Sensor, K. Wang, H. Wang, C. Li, Z. Yin, R. Xiao, Q. Li, Y. Xiang, W. Wang, J. Huang, L. Chen, P. Fang, K. Liang, 2021 Three-dimensional oxabicycloheptene sulfonate targets the homologous recombination and repair programmes through estrogen receptor alpha antagonism, J. Wu, J. Yan, P. Fang, H.B. Zhou, K. Liang, J. Huang, 2020 Genome-scale CRISPR knockout screen identifies TIGAR as a modifier of PARP inhibitor sensitivity, Fang, P., De Souza, C., Minn, K., Chien, J., 2019 Olaparib-induced Adaptive Response Is Disrupted by FOXM1 Targeting that Enhances Sensitivity to PARP Inhibition, Fang, P., Madden, J.A., Neums, L., Moulder, R.K., Forrest, M.L., Chien, J., 2018

Areas of Focus

Development of genomic and proteomic research methods
Study of drug resistance in targeted therapies and exploration of new targeted treatment strategies

Publications

CDK12 and Integrator-PP2A Complex Modulates LEO1 Phosphorylation for Processive Transcription Elongation, Qiu M., Yin Z., Wang H., Lei L., Li C., Cui Y., Dai R., Yang P., Xiang Y., Li Q., Lv J., Hu Z., Chen M., Zhou H., Fang, P.*, Xiao R.*, Liang K.*, 2023
G-quadruplexes sense natural porphyrin metabolites for regulation of gene transcription and chromatin landscapes, Li C., Yin Z., Xiao R., Huang B., Cui Y., Wang H., Xiang Y., Wang L., Lei L., Ye J., Li T., Zhong Y., Guo F., Xia Y., Fang P.*, Liang K.*, 2022
Discovery of Novel Bicyclic Phenylselenyl-Containing Hybrids: An Orally Bioavailable, Potential, and Multiacting Class of Estrogen Receptor Modulators against Endocrine-Resistant Breast Cancer, X. Deng, B. Xie, Q. Li, Y. Xiao, Z. Hu, X. Deng, P. Fang*, C. Dong*, H. Zhou*, J. Huang*, 2022
Ligand-induced Native G-quadruplexes Stabilization Impairs Transcription Initiation, C. Li, H. Wang, Z. Yin, P. Fang, R. Xiao, Y. Xiang, W. Wang, Q. Li, B. Huang, J. Huang, K. Liang*, 2021
Genomic Profiling of Native R-loops with a DNA-RNA Hybrid Recognition Sensor, K. Wang, H. Wang, C. Li, Z. Yin, R. Xiao, Q. Li, Y. Xiang, W. Wang, J. Huang, L. Chen, P. Fang, K. Liang*, 2021
Three-dimensional oxabicycloheptene sulfonate targets the homologous recombination and repair programmes through estrogen receptor alpha antagonism, J. Wu, J. Yan, P. Fang, H.B. Zhou, K. Liang, J. Huang*, 2020
Genome-scale CRISPR knockout screen identifies TIGAR as a modifier of PARP inhibitor sensitivity, Fang, P., De Souza, C., Minn, K., Chien, J*., 2019
Olaparib-induced Adaptive Response Is Disrupted by FOXM1 Targeting that Enhances Sensitivity to PARP Inhibition, Fang, P., Madden, J.A., Neums, L., Moulder, R.K., Forrest, M.L., Chien, J*., 2018

Genomics Proteomics Research Methods Drug Resistance Targeted Therapies Treatment Strategies Dna Damage Gene Transcription Regulation Inhibitors

Jun Che - Southern University of Science and Technology

Dewei Jiang - University of Chinese Academy of Sciences

Bai Shan Jiang - Wuhan University

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