Professor | Lianrong Wang | Asia Growth Partners

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Name	Lianrong Wang
Contact Information	lianrong@whu.edu.cn
Language ability	English, Chinese
Province	Hubei

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Name

Lianrong Wang

Contact Information

lianrong@whu.edu.cn

Language ability

English, Chinese

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Medical School
Academic Background & Achievements	2003-2008 PhD, Shanghai Jiao Tong University, School of Life Sciences 1999-2003 Bachelor, Shandong University, School of Life Sciences
Work Experience	2011-Present Professor, School of Pharmacy, Wuhan University 2008-2011 Postdoctoral Researcher, Department of Biological Engineering, MIT 2006-2008 Visiting PhD Student, Department of Biological Engineering, MIT
Awards	2023 Chinese Young Female Scientist Award 2022 Chief Scientist of Key Projects of the Ministry of Science and Technology 2021 National Science Foundation for Distinguished Young Scholars 2021 Outstanding Young Faculty of Wuhan University 2018 Zhu Yubi Medical Award of Wuhan University 2016 Outstanding Medical Contribution Award of Wuhan University 2015 Young Top-notch Talent of the Organization Department 2015 First Prize in Natural Science of the Higher Education Outstanding Research Achievement Awards (3) 2014 Outstanding Medical Contribution Award of Wuhan University 2012 National Science Foundation for Excellent Young Scholars 2011 New Century Excellent Talents in University 2010 National Excellent Doctoral Dissertation 2009 Young Investigator of Bioanalysis 2009 Shanghai Excellent Doctoral Dissertation 2007 Top Ten Scientific News of Global Science 2007 Meiji Dairy Life Science Award

University/Lab Affiliation and Title

Wuhan University

Faculty

Medical School

Academic Background & Achievements

2003-2008 PhD, Shanghai Jiao Tong University, School of Life Sciences
1999-2003 Bachelor, Shandong University, School of Life Sciences

Work Experience

2011-Present Professor, School of Pharmacy, Wuhan University
2008-2011 Postdoctoral Researcher, Department of Biological Engineering, MIT
2006-2008 Visiting PhD Student, Department of Biological Engineering, MIT

Awards

2023 Chinese Young Female Scientist Award
2022 Chief Scientist of Key Projects of the Ministry of Science and Technology
2021 National Science Foundation for Distinguished Young Scholars
2021 Outstanding Young Faculty of Wuhan University
2018 Zhu Yubi Medical Award of Wuhan University
2016 Outstanding Medical Contribution Award of Wuhan University
2015 Young Top-notch Talent of the Organization Department
2015 First Prize in Natural Science of the Higher Education Outstanding Research Achievement Awards (3)
2014 Outstanding Medical Contribution Award of Wuhan University
2012 National Science Foundation for Excellent Young Scholars
2011 New Century Excellent Talents in University
2010 National Excellent Doctoral Dissertation
2009 Young Investigator of Bioanalysis
2009 Shanghai Excellent Doctoral Dissertation
2007 Top Ten Scientific News of Global Science
2007 Meiji Dairy Life Science Award

Areas of Focus	Genomic phosphorothioate modification and synthetic biology Epigenetic and biomedical applications
Publications	SspABCD-SspE is a phosphorothioation-sensing bacterial defense system with broad antiphage activities, Lianrong Wang, 2020 The functional coupling between restriction and DNA phosphorothioate modification systems underlying the DndFGH restriction complex, Lianrong Wang, 2022 Epigenetic Competition Reveals Density-Dependent Regulation and Target Site Plasticity of Phosphorothioate Epigenetics in Bacteria, Lianrong Wang, 2020 Systematic strategies for developing phage resistant Escherichia coli strains, Lianrong Wang, 2022 Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE, Lianrong Wang, 2022 Engineered Phage with Aggregation-Induced Emission Photosensitizer in Cocktail Therapy against Sepsis, Lianrong Wang A Membrane-Targeted Photosensitizer Prevents Drug Resistance and Induces Immune Response in Treating Candidiasis, Lianrong Wang, 2023 Single-molecule optical mapping of the distribution of DNA phosphorothioate epigenetics, Lianrong Wang, 2021 A Membrane-Targeting Photosensitizer with Aggregation-Induced Emission Characteristics for Highly Efficient Photodynamic Combat of Human Coronaviruses, Lianrong Wang, 2021 Genomic mapping of phosphorothioates reveals partial modification of short consensus sequences, Lianrong Wang, 2014 C9orf72 regulates the unfolded protein response and stress granule formation by interacting with eIF2α, Lianrong Wang, 2022 Involvement of the DNA Phosphorothioation System in TorR Binding and Anaerobic TMAO Respiration in Salmonella enterica, Lianrong Wang, 2022 Structural and Functional Analysis of DndE Involved in DNA Phosphorothioation in the Haloalkaliphilic Archaea Natronorubrum bangense JCM10635, Lianrong Wang, 2022 Gut microbiome interventions in human health and diseases, Lianrong Wang, 2019 Pathological convergence of APP and SNCA deficiency in hippocampal degeneration of young rats, Lianrong Wang, 2023 Aggregation-induced emission: recent applications in infectious diseases, Lianrong Wang, 2023 Phosphorothioation of DNA in bacteria by dnd genes, Lianrong Wang, 2007 DNA phosphorothioation is widespread and quantized in bacterial genomes, Lianrong Wang, 2011

Areas of Focus

Genomic phosphorothioate modification and synthetic biology
Epigenetic and biomedical applications

Publications

SspABCD-SspE is a phosphorothioation-sensing bacterial defense system with broad antiphage activities, Lianrong Wang*, 2020
The functional coupling between restriction and DNA phosphorothioate modification systems underlying the DndFGH restriction complex, Lianrong Wang*, 2022
Epigenetic Competition Reveals Density-Dependent Regulation and Target Site Plasticity of Phosphorothioate Epigenetics in Bacteria, Lianrong Wang*, 2020
Systematic strategies for developing phage resistant Escherichia coli strains, Lianrong Wang*, 2022
Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE, Lianrong Wang*, 2022
Engineered Phage with Aggregation-Induced Emission Photosensitizer in Cocktail Therapy against Sepsis, Lianrong Wang*
A Membrane-Targeted Photosensitizer Prevents Drug Resistance and Induces Immune Response in Treating Candidiasis, Lianrong Wang*, 2023
Single-molecule optical mapping of the distribution of DNA phosphorothioate epigenetics, Lianrong Wang*, 2021
A Membrane-Targeting Photosensitizer with Aggregation-Induced Emission Characteristics for Highly Efficient Photodynamic Combat of Human Coronaviruses, Lianrong Wang*, 2021
Genomic mapping of phosphorothioates reveals partial modification of short consensus sequences, Lianrong Wang*, 2014
C9orf72 regulates the unfolded protein response and stress granule formation by interacting with eIF2α, Lianrong Wang*, 2022
Involvement of the DNA Phosphorothioation System in TorR Binding and Anaerobic TMAO Respiration in Salmonella enterica, Lianrong Wang*, 2022
Structural and Functional Analysis of DndE Involved in DNA Phosphorothioation in the Haloalkaliphilic Archaea Natronorubrum bangense JCM10635, Lianrong Wang*, 2022
Gut microbiome interventions in human health and diseases, Lianrong Wang*, 2019
Pathological convergence of APP and SNCA deficiency in hippocampal degeneration of young rats, Lianrong Wang*, 2023
Aggregation-induced emission: recent applications in infectious diseases, Lianrong Wang*, 2023
Phosphorothioation of DNA in bacteria by dnd genes, Lianrong Wang*, 2007
DNA phosphorothioation is widespread and quantized in bacterial genomes, Lianrong Wang*, 2011

Dna Modification Phosphorothioate Synthetic Biology Defense Systems Gene Expression Oxidative-Reduction Balance Antiphage Engineering Pathogenic Bacteria Drug Resistance Phage Therapy

Shiyun Chen - University of Chinese Academy of Sciences

Cuihua Liu - University of Chinese Academy of Sciences

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