Professor | Jing Chen | Asia Growth Partners

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Name	Jing Chen
Contact Information	364580342@qq.com
Language ability	English, Chinese
Province	Hubei

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Name

Jing Chen

Contact Information

364580342@qq.com

Language ability

English, Chinese

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Medical School
Academic Background & Achievements	2000.09-2005.07 Wuhan University - Bachelor of Medicine 2005.09-2007.07 Wuhan University - Master of Medicine 2008.09-2011.08 Wuhan University - Doctor of Medicine 2008.08-2010.06 Georgia Institute of Technology, USA - Visiting Scholar Hosted 2 National Natural Science Foundation projects, undertook 8, hosted Ministry of Education doctoral fund and central university young teacher fund each one. Published over 30 SCI papers, participated in 4 books.
Work Experience	2011.07-2011.12 Wuhan University Renmin Hospital - Resident Physician 2012.01-2013.12 Wuhan University Renmin Hospital - Attending Physician 2014.01-2019.03 Wuhan University Renmin Hospital - Associate Chief Physician 2015.01-2021.07 Wuhan University Renmin Hospital - Associate Professor 2016.06-present Wuhan University Renmin Hospital - Master's Supervisor 2018.06-present Wuhan University Renmin Hospital - Director of Cardiology V Department 2019.03-present Wuhan University Renmin Hospital - Chief Physician 2022.07-present Wuhan University Renmin Hospital - Doctoral Supervisor
Awards	Advanced Individual in Fighting the Epidemic by China Democratic League (Year not mentioned) Advanced Individual in Fighting COVID-19 by Hubei Provincial Committee of the China Democratic League (Year not mentioned) 2020 Second Elite Cardiovascular Disease Anti-Epidemic Hero Award Hubei Province Natural Science Award 2015: Research on Vascular and Myocardial Injury and Repair Mechanisms Hubei Province Science and Technology Progress Award 2014: Mechanism and Prevention Strategy of Neointimal Hyperplasia Mediated by HMGB1 after Vascular Injury Wuhan Young Backbone Talent 8th Wuhan University Young Teacher Teaching Competition National Interventional Cardiology Conference IABP Scholarship Outstanding Case Great Wall Young Physician Award

University/Lab Affiliation and Title

Wuhan University

Faculty

Medical School

Academic Background & Achievements

2000.09-2005.07 Wuhan University - Bachelor of Medicine
2005.09-2007.07 Wuhan University - Master of Medicine
2008.09-2011.08 Wuhan University - Doctor of Medicine
2008.08-2010.06 Georgia Institute of Technology, USA - Visiting Scholar
Hosted 2 National Natural Science Foundation projects, undertook 8, hosted Ministry of Education doctoral fund and central university young teacher fund each one. Published over 30 SCI papers, participated in 4 books.

Work Experience

2011.07-2011.12 Wuhan University Renmin Hospital - Resident Physician
2012.01-2013.12 Wuhan University Renmin Hospital - Attending Physician
2014.01-2019.03 Wuhan University Renmin Hospital - Associate Chief Physician
2015.01-2021.07 Wuhan University Renmin Hospital - Associate Professor
2016.06-present Wuhan University Renmin Hospital - Master's Supervisor
2018.06-present Wuhan University Renmin Hospital - Director of Cardiology V Department
2019.03-present Wuhan University Renmin Hospital - Chief Physician
2022.07-present Wuhan University Renmin Hospital - Doctoral Supervisor

Awards

Advanced Individual in Fighting the Epidemic by China Democratic League (Year not mentioned)
Advanced Individual in Fighting COVID-19 by Hubei Provincial Committee of the China Democratic League (Year not mentioned)
2020 Second Elite Cardiovascular Disease Anti-Epidemic Hero Award
Hubei Province Natural Science Award 2015: Research on Vascular and Myocardial Injury and Repair Mechanisms
Hubei Province Science and Technology Progress Award 2014: Mechanism and Prevention Strategy of Neointimal Hyperplasia Mediated by HMGB1 after Vascular Injury
Wuhan Young Backbone Talent
8th Wuhan University Young Teacher Teaching Competition
National Interventional Cardiology Conference IABP Scholarship Outstanding Case
Great Wall Young Physician Award

Areas of Focus	Vascular and myocardial injury and repair mechanisms Interventional cardiology
Publications	The histone demethylase KDM3A protects the myocardium from ischemia/reperfusion injury via promotion of ETS1 expression, Guo X, Zhang BF, Zhang J, Liu G, Hu Q, Chen J, 2022 KDM3A Inhibition Ameliorates Hyperglycemia-Mediated Myocardial Injury by Epigenetic Modulation of Nuclear Factor Kappa-B/P65, Zhang B, Zhang J, Liu G, Guo X, Liu X, Chen J, 2022 MicroRNA-17-5p, a novel endothelial cell modulator, controls vascular re-endothelialization and neointimal lesion formation, Liu X, Chen J, Liu G, Zhang B, Jin X, Wang Y, 2021 In-Hospital Management and Outcomes of Acute Myocardial Infarction Before and During the Coronavirus Disease 2019 Pandemic, Huang B, Xu C, Liu H, Deng W, Yang Z, Wan J, Yan H, Cao G, Chen J, Jiang H, 2020 Lysine demethylase 3A is a positive regulator of cardiac myofibroblast transdifferentiation that increases Smad3 phosphorylation following transforming growth factor beta1 stimulation, Liu X, Zhou J, Zhang B, Liu G, Hu Q, Chen J, 2022 Down-regulation of Suv39h1 attenuates neointima formation after carotid artery injury in diabetic rats, Zhang J, Yang J, Xu C, Hu Q, Hu J, Chen J, Jiang H, 2020 LncRNA H19 ameliorates myocardial infarction-induced myocardial injury and maladaptive cardiac remodeling by regulating KDM3A, Zhang BF, Jiang H, Chen J, Hu Q, Yang S, Liu XP, Liu G, 2020 Silica-coated magnetic nanoparticles labeled endothelial progenitor cells alleviate ischemic myocardial injury and improve long-term cardiac function with magnetic field guidance in rats with myocardial infarction, Zhang BF, Jiang H, Chen J, Hu Q, Yang S, Liu XP, 2019 Nobiletin ameliorates myocardial ischemia and reperfusion injury by attenuating endoplasmic reticulum stress-associated apoptosis through regulation of the PI3K/AKT signal pathway, Zhang BF, Jiang H, Chen J, Guo X, Li Y, Hu Q, Yang S, 2019 LncRNA H19 ameliorates myocardial ischemia-reperfusion injury by targeting miR-22-3P, Zhang BF, Chen J, Jiang H, 2019 KDM3A inhibition modulates macrophage polarization to aggravate post-MI injuries and accelerates adverse ventricular remodeling via an IRF4 signaling pathway, Liu X, Chen J, Zhang B, Liu G, Zhao H, Hu Q, 2019 RING finger protein 10 prevents neointimal hyperplasia by promoting apoptosis in vitro and in vivo, Yu G, Chen J, Li S, Pu P, Huang W, Zhao Y, Peng X, Wang R, Lei H, 2018 JDP2: A novel therapeutic thought in cardiac remodeling, Guo X, Hu S, Chen J, Jiang H, 2018 Histone demethylase KDM3a, a novel regulator of vascular smooth muscle cells, controls vascular neointimal hyperplasia in diabetic rats, Chen J, Zhang J, Yang J, Xu L, Hu Q, Xu C, Yang S, Jiang H, 2017 DPP-4 inhibition as a therapeutic strategy to ameliorate diabetic metabolic memory, Guo X, Zhang BF, Chen J, Jiang H, 2017 RP105-PI3K-Akt axis: A potential therapeutic approach for ameliorating myocardial ischemia/reperfusion injury, Guo X, Jiang H, Chen J, 2016 MiR-17-5p as circulating biomarkers for the severity of coronary atherosclerosis in coronary artery disease, Chen J, Xu L, Hu Q, Yang S, Zhang B, Jiang H, 2015 Down-regulation of CREB-binding protein expression blocks thrombin-mediated endothelial activation by inhibiting acetylation of NF-κB, Chen J, Jiang H, Yang J, Chen SS, Xu L, 2012 Inhibition of neointimal hyperplasia in the rat carotid artery injury model by a HMGB1 inhibitor, Chen J, Zhang J, Xu L, Xu C, Chen S, Yang J, Jiang H, 2012 Overexpression of miR-429 induces mesenchymal

Areas of Focus

Vascular and myocardial injury and repair mechanisms
Interventional cardiology

Publications

The histone demethylase KDM3A protects the myocardium from ischemia/reperfusion injury via promotion of ETS1 expression, Guo X, Zhang BF, Zhang J, Liu G, Hu Q, Chen J, 2022
KDM3A Inhibition Ameliorates Hyperglycemia-Mediated Myocardial Injury by Epigenetic Modulation of Nuclear Factor Kappa-B/P65, Zhang B, Zhang J, Liu G, Guo X, Liu X, Chen J, 2022
MicroRNA-17-5p, a novel endothelial cell modulator, controls vascular re-endothelialization and neointimal lesion formation, Liu X, Chen J, Liu G, Zhang B, Jin X, Wang Y, 2021
In-Hospital Management and Outcomes of Acute Myocardial Infarction Before and During the Coronavirus Disease 2019 Pandemic, Huang B, Xu C, Liu H, Deng W, Yang Z, Wan J, Yan H, Cao G, Chen J, Jiang H, 2020
Lysine demethylase 3A is a positive regulator of cardiac myofibroblast transdifferentiation that increases Smad3 phosphorylation following transforming growth factor beta1 stimulation, Liu X, Zhou J, Zhang B, Liu G, Hu Q, Chen J, 2022
Down-regulation of Suv39h1 attenuates neointima formation after carotid artery injury in diabetic rats, Zhang J, Yang J, Xu C, Hu Q, Hu J, Chen J, Jiang H, 2020
LncRNA H19 ameliorates myocardial infarction-induced myocardial injury and maladaptive cardiac remodeling by regulating KDM3A, Zhang BF, Jiang H, Chen J, Hu Q, Yang S, Liu XP, Liu G, 2020
Silica-coated magnetic nanoparticles labeled endothelial progenitor cells alleviate ischemic myocardial injury and improve long-term cardiac function with magnetic field guidance in rats with myocardial infarction, Zhang BF, Jiang H, Chen J, Hu Q, Yang S, Liu XP, 2019
Nobiletin ameliorates myocardial ischemia and reperfusion injury by attenuating endoplasmic reticulum stress-associated apoptosis through regulation of the PI3K/AKT signal pathway, Zhang BF, Jiang H, Chen J, Guo X, Li Y, Hu Q, Yang S, 2019
LncRNA H19 ameliorates myocardial ischemia-reperfusion injury by targeting miR-22-3P, Zhang BF, Chen J, Jiang H, 2019
KDM3A inhibition modulates macrophage polarization to aggravate post-MI injuries and accelerates adverse ventricular remodeling via an IRF4 signaling pathway, Liu X, Chen J, Zhang B, Liu G, Zhao H, Hu Q, 2019
RING finger protein 10 prevents neointimal hyperplasia by promoting apoptosis in vitro and in vivo, Yu G, Chen J, Li S, Pu P, Huang W, Zhao Y, Peng X, Wang R, Lei H, 2018
JDP2: A novel therapeutic thought in cardiac remodeling, Guo X, Hu S, Chen J, Jiang H, 2018
Histone demethylase KDM3a, a novel regulator of vascular smooth muscle cells, controls vascular neointimal hyperplasia in diabetic rats, Chen J, Zhang J, Yang J, Xu L, Hu Q, Xu C, Yang S, Jiang H, 2017
DPP-4 inhibition as a therapeutic strategy to ameliorate diabetic metabolic memory, Guo X, Zhang BF, Chen J, Jiang H, 2017
RP105-PI3K-Akt axis: A potential therapeutic approach for ameliorating myocardial ischemia/reperfusion injury, Guo X, Jiang H, Chen J, 2016
MiR-17-5p as circulating biomarkers for the severity of coronary atherosclerosis in coronary artery disease, Chen J, Xu L, Hu Q, Yang S, Zhang B, Jiang H, 2015
Down-regulation of CREB-binding protein expression blocks thrombin-mediated endothelial activation by inhibiting acetylation of NF-κB, Chen J, Jiang H, Yang J, Chen SS, Xu L, 2012
Inhibition of neointimal hyperplasia in the rat carotid artery injury model by a HMGB1 inhibitor, Chen J, Zhang J, Xu L, Xu C, Chen S, Yang J, Jiang H, 2012
Overexpression of miR-429 induces mesenchymal

Vascular Repair Myocardial Repair Interventional Cardiology Coronary Heart Disease Vascular Injury Heart Failure Stent Implantation Coronary Angiography Clinical Research Basic Research

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