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Jing Chen
Medical School
Wuhan University
Hubei
Language: English, Chinese
Vascular Repair
Myocardial Repair
Interventional Cardiology
Coronary Heart Disease
Vascular Injury
Heart Failure
Stent Implantation
Coronary Angiography
Clinical Research
Basic Research
Areas of Focus
- Vascular and myocardial injury and repair mechanisms
- Interventional cardiology
Work Experience
- 2011.07-2011.12 Wuhan University Renmin Hospital - Resident Physician
- 2012.01-2013.12 Wuhan University Renmin Hospital - Attending Physician
- 2014.01-2019.03 Wuhan University Renmin Hospital - Associate Chief Physician
- 2015.01-2021.07 Wuhan University Renmin Hospital - Associate Professor
- 2016.06-present Wuhan University Renmin Hospital - Master's Supervisor
- 2018.06-present Wuhan University Renmin Hospital - Director of Cardiology V Department
- 2019.03-present Wuhan University Renmin Hospital - Chief Physician
- 2022.07-present Wuhan University Renmin Hospital - Doctoral Supervisor
Academic Background & Achievements
- 2000.09-2005.07 Wuhan University - Bachelor of Medicine
- 2005.09-2007.07 Wuhan University - Master of Medicine
- 2008.09-2011.08 Wuhan University - Doctor of Medicine
- 2008.08-2010.06 Georgia Institute of Technology, USA - Visiting Scholar
- Hosted 2 National Natural Science Foundation projects, undertook 8, hosted Ministry of Education doctoral fund and central university young teacher fund each one. Published over 30 SCI papers, participated in 4 books.
Publications
- The histone demethylase KDM3A protects the myocardium from ischemia/reperfusion injury via promotion of ETS1 expression, Guo X, Zhang BF, Zhang J, Liu G, Hu Q, Chen J, 2022
- KDM3A Inhibition Ameliorates Hyperglycemia-Mediated Myocardial Injury by Epigenetic Modulation of Nuclear Factor Kappa-B/P65, Zhang B, Zhang J, Liu G, Guo X, Liu X, Chen J, 2022
- MicroRNA-17-5p, a novel endothelial cell modulator, controls vascular re-endothelialization and neointimal lesion formation, Liu X, Chen J, Liu G, Zhang B, Jin X, Wang Y, 2021
- In-Hospital Management and Outcomes of Acute Myocardial Infarction Before and During the Coronavirus Disease 2019 Pandemic, Huang B, Xu C, Liu H, Deng W, Yang Z, Wan J, Yan H, Cao G, Chen J, Jiang H, 2020
- Lysine demethylase 3A is a positive regulator of cardiac myofibroblast transdifferentiation that increases Smad3 phosphorylation following transforming growth factor beta1 stimulation, Liu X, Zhou J, Zhang B, Liu G, Hu Q, Chen J, 2022
- Down-regulation of Suv39h1 attenuates neointima formation after carotid artery injury in diabetic rats, Zhang J, Yang J, Xu C, Hu Q, Hu J, Chen J, Jiang H, 2020
- LncRNA H19 ameliorates myocardial infarction-induced myocardial injury and maladaptive cardiac remodeling by regulating KDM3A, Zhang BF, Jiang H, Chen J, Hu Q, Yang S, Liu XP, Liu G, 2020
- Silica-coated magnetic nanoparticles labeled endothelial progenitor cells alleviate ischemic myocardial injury and improve long-term cardiac function with magnetic field guidance in rats with myocardial infarction, Zhang BF, Jiang H, Chen J, Hu Q, Yang S, Liu XP, 2019
- Nobiletin ameliorates myocardial ischemia and reperfusion injury by attenuating endoplasmic reticulum stress-associated apoptosis through regulation of the PI3K/AKT signal pathway, Zhang BF, Jiang H, Chen J, Guo X, Li Y, Hu Q, Yang S, 2019
- LncRNA H19 ameliorates myocardial ischemia-reperfusion injury by targeting miR-22-3P, Zhang BF, Chen J, Jiang H, 2019
- KDM3A inhibition modulates macrophage polarization to aggravate post-MI injuries and accelerates adverse ventricular remodeling via an IRF4 signaling pathway, Liu X, Chen J, Zhang B, Liu G, Zhao H, Hu Q, 2019
- RING finger protein 10 prevents neointimal hyperplasia by promoting apoptosis in vitro and in vivo, Yu G, Chen J, Li S, Pu P, Huang W, Zhao Y, Peng X, Wang R, Lei H, 2018
- JDP2: A novel therapeutic thought in cardiac remodeling, Guo X, Hu S, Chen J, Jiang H, 2018
- Histone demethylase KDM3a, a novel regulator of vascular smooth muscle cells, controls vascular neointimal hyperplasia in diabetic rats, Chen J, Zhang J, Yang J, Xu L, Hu Q, Xu C, Yang S, Jiang H, 2017
- DPP-4 inhibition as a therapeutic strategy to ameliorate diabetic metabolic memory, Guo X, Zhang BF, Chen J, Jiang H, 2017
- RP105-PI3K-Akt axis: A potential therapeutic approach for ameliorating myocardial ischemia/reperfusion injury, Guo X, Jiang H, Chen J, 2016
- MiR-17-5p as circulating biomarkers for the severity of coronary atherosclerosis in coronary artery disease, Chen J, Xu L, Hu Q, Yang S, Zhang B, Jiang H, 2015
- Down-regulation of CREB-binding protein expression blocks thrombin-mediated endothelial activation by inhibiting acetylation of NF-κB, Chen J, Jiang H, Yang J, Chen SS, Xu L, 2012
- Inhibition of neointimal hyperplasia in the rat carotid artery injury model by a HMGB1 inhibitor, Chen J, Zhang J, Xu L, Xu C, Chen S, Yang J, Jiang H, 2012
- Overexpression of miR-429 induces mesenchymal
Awards
- Advanced Individual in Fighting the Epidemic by China Democratic League (Year not mentioned)
- Advanced Individual in Fighting COVID-19 by Hubei Provincial Committee of the China Democratic League (Year not mentioned)
- 2020 Second Elite Cardiovascular Disease Anti-Epidemic Hero Award
- Hubei Province Natural Science Award 2015: Research on Vascular and Myocardial Injury and Repair Mechanisms
- Hubei Province Science and Technology Progress Award 2014: Mechanism and Prevention Strategy of Neointimal Hyperplasia Mediated by HMGB1 after Vascular Injury
- Wuhan Young Backbone Talent
- 8th Wuhan University Young Teacher Teaching Competition
- National Interventional Cardiology Conference IABP Scholarship Outstanding Case
- Great Wall Young Physician Award
