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Hongjing Guan
Medical School
Wuhan University
Hubei
Language: Chinese, English
Vascular
Cardiac
Remodeling
Molecular Mechanisms
Cardiovascular Diseases
Atherosclerosis
Neointima
Smooth Muscle Cells
Inflammation
Cell Proliferation
Areas of Focus
- Molecular mechanisms of vascular and cardiac remodeling
Work Experience
- 1995-2002 - Zhenhai Refining & Chemical Hospital, Ningbo - Attending Physician
- 2008-2012 - Renmin Hospital of Wuhan University, Cardiology - Attending Physician
- 2012-2013 - Renmin Hospital of Wuhan University, Cardiology - Associate Chief Physician
- 2013-Present - Renmin Hospital of Wuhan University, Cardiology - Associate Chief Physician, Associate Professor
Academic Background & Achievements
- 1990-1995 Bachelor: Hunan Medical University
- 2002-2005 Master: Wuhan University Medical School, Cardiology
- 2005-2008 PhD: Huazhong University of Science and Technology, Tongji Medical College, Cardiology
Publications
- Vinexin β Ablation Inhibits Atherosclerosis in Apolipoprotein E-Deficient Mice by Inactivating the Akt-Nuclear Factor κB Inflammatory Axis, Guan H, Cheng WL, Guo J, Chao ML, Zhang Y, Gong J, Zhu XY, She ZG, Huang Z, Li H, 2017
- Indole-3-carbinol blocks platelet-derived growth factor-stimulated vascular smooth muscle cell function and reduces neointima formation in vivo, Guan H, Chen C, Zhu L, Cui C, Guo Y, Fu M, Wang L, Tang Q, 2013
- 3,3'Diindolylmethane suppresses vascular smooth muscle cell phenotypic modulation and inhibits neointima formation after carotid injury, Guan H, Zhu L, Fu M, Yang D, Tian S, Guo Y, Cui C, Wang L, Jiang H, 2012
- Apigenin attenuates neointima formation via suppression of vascular smooth muscle cell phenotypic transformation, Guan H, Gao L, Zhu L, Yan L, Fu M, Chen C, Dong X, Wang L, Huang K, Jiang H, 2012
- Adeno-associated virus-mediated human C-reactive protein gene delivery causes endothelial dysfunction and hypertension in rats, Guan H, Wang P, Hui R, Edin ML, Zeldin DC, Wang DW, 2009
- Effect of sinomenine on vascular smooth muscle cell dedifferentiation and neointima formation after vascular injury in mice, Zhu L, Hao Y, Guan H, Cui C, Tian S, Yang D, Wang X, Zhang S, Wang L, Jiang H, 2013
- Gastrodin inhibits cell proliferation in vascular smooth muscle cells and attenuates neointima formation in vivo, Zhu L, Guan H, Cui C, Tian S, Yang D, Wang X, Zhang S, Wang L, Jiang H, 2012
- Disruption of tumor necrosis factor receptor associated factor 5 exacerbates pressure overload cardiac hypertrophy and fibrosis, Bian Z, Dai J, Hiroyasu N, Guan H, Yuan Y, Gan L, Zhou H, Zong J, Zhang Y, Li F, Yan L, Shen D, Li H, Tang Q
- Tumor necrosis factor receptor-associated factor 5 is an essential mediator of ischemic brain infarction, Wang L, Lu Y, Guan H, Jiang D, Guan Y, Zhang X, Nakano H, Zhou Y, Zhang Y, Yang L, Li H, 2013
- Mindin regulates vascular smooth muscle cell phenotype and prevents neointima formation, Zhu LH, Huang L, Zhang X, Zhang P, Zhang SM, Guan H, Zhang Y, Zhu XY, Tian S, Deng K, Li H, 2015
- Interferon regulatory factor 3 protects against adverse neo-intima formation, Zhang SM, Zhu LH, Li ZZ, Wang PX, Chen HZ, Guan HJ, Jiang DS, Chen K, Zhang XF, Tian S, Yang D, Zhang XD, Li H, 2014
- Cellular FLICE-inhibitory protein protects against cardiac remodelling after myocardial infarction, Xiao J, Moon M, Yan L, Nian M, Zhang Y, Liu C, Lu J, Guan H, Chen M, Jiang D, Jiang H, Liu PP, Li H, 2012
Awards
- Hubei Province Natural Science Award, Third Prize
