Professor | Heng Zhou | Asia Growth Partners

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Name	Heng Zhou
Contact Information	hengzhou@whu.edu.cn
Language ability	Chinese, English
Province	Hubei

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Name

Heng Zhou

Contact Information

hengzhou@whu.edu.cn

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Medical School
Academic Background & Achievements	2002-2007: Bachelor of Clinical Medicine, Wuhan University 2007-2012: PhD in Internal Medicine, Wuhan University Hosted 2 National Natural Science Foundation projects, 1 Fundamental Research Funds for the Central Universities project, and 1 Hubei Provincial Health Commission research project
Work Experience	2012.07-2012.11: Physician, Cardiovascular Department, Renmin Hospital, Wuhan University 2012.11-2015.11: Attending Physician, Cardiovascular Department, Renmin Hospital, Wuhan University 2015.11-present: Vice Director, Cardiovascular Department, Renmin Hospital, Wuhan University 2016.11-present: Vice Professor, Cardiovascular Department, Renmin Hospital, Wuhan University
Awards	2019: First Class Prize of Hubei Provincial Scientific and Technological Progress Award for 'Structural Remodeling and Prevention of Heart Failure' 2013: First Class Prize of Hubei Provincial Scientific and Technological Progress Award for 'Mechanism and Clinical Prevention of Cardiac Remodeling' 2013: First Class Prize of Wuhan Municipal Scientific and Technological Progress Award for 'Mechanism and Clinical Prevention of Cardiac Remodeling'

University/Lab Affiliation and Title

Wuhan University

Faculty

Medical School

Academic Background & Achievements

2002-2007: Bachelor of Clinical Medicine, Wuhan University
2007-2012: PhD in Internal Medicine, Wuhan University
Hosted 2 National Natural Science Foundation projects, 1 Fundamental Research Funds for the Central Universities project, and 1 Hubei Provincial Health Commission research project

Work Experience

2012.07-2012.11: Physician, Cardiovascular Department, Renmin Hospital, Wuhan University
2012.11-2015.11: Attending Physician, Cardiovascular Department, Renmin Hospital, Wuhan University
2015.11-present: Vice Director, Cardiovascular Department, Renmin Hospital, Wuhan University
2016.11-present: Vice Professor, Cardiovascular Department, Renmin Hospital, Wuhan University

Awards

2019: First Class Prize of Hubei Provincial Scientific and Technological Progress Award for 'Structural Remodeling and Prevention of Heart Failure'
2013: First Class Prize of Hubei Provincial Scientific and Technological Progress Award for 'Mechanism and Clinical Prevention of Cardiac Remodeling'
2013: First Class Prize of Wuhan Municipal Scientific and Technological Progress Award for 'Mechanism and Clinical Prevention of Cardiac Remodeling'

Areas of Focus	Cardiac remodeling Heart failure
Publications	TMEM173 protects against pressure overload-induced cardiac hypertrophy by modulating autophagy, Jin YG, Zhou H, Fan D, Che Y, Wang ZP, Wang SS, Tang QZ, 2020 Leukocyte immunoglobulin-like receptor B4 protects against cardiac hypertrophy via SHP-2-dependent inhibition of the NF-κB pathway, Zhou H, Li N, Yuan Y, Jin YG, Wu Q, Yan L, Bian ZY, Deng W, Shen DF, Li H, Tang QZ, 2020 STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3, Li N, Zhou H, Wu H, Wu Q, Duan M, Deng W, Tang Q, 2019 Andrographolide Protects against HG-Induced Inflammation, Apoptosis, Migration, and Impairment of Angiogenesis via PI3K/AKT-eNOS Signalling in HUVECs, Duan MX, Zhou H, Wu QQ, Liu C, Xiao Y, Deng W, Tang QZ, 2019 Antioxidative Property and Molecular Mechanisms Underlying Geniposide-Mediated Therapeutic Effects in Diabetes Mellitus and Cardiovascular Disease, Li N, Li L, Wu H, Zhou H, 2019 Geniposide Alleviates Isoproterenol-Induced Cardiac Fibrosis Partially via SIRT1 Activation in vivo and in vitro, Li N, Zhou H, Ma ZG, Zhu JX, Liu C, Song P, Kong CY, Wu HM, Deng W, Tang QZ, 2018 Activating transcription factor 3 in cardiovascular diseases: a potential therapeutic target, Zhou H, Li N, Yuan Y, Jin YG, Guo H, Deng W, Tang QZ, 2018 miR-133: A Suppressor of Cardiac Remodeling?, Li N, Zhou H, Tang Q, 2018 Red Blood Cell Distribution Width: A Novel Predictive Indicator for Cardiovascular and Cerebrovascular Diseases, Li N, Zhou H, Tang Q, 2017 Puerarin attenuates the inflammatory response and apoptosis in LPS-stimulated cardiomyocytes, Yuan Y, Zhou H, Wu QQ, Li FF, Bian ZY, Deng W, Zhou MQ, Tang QZ, 2016 Pleiotropic and puzzling effects of ATF3 in maladaptive cardiac remodeling, Zhou H, Yuan Y, Ni J, Guo H, Deng W, Bian ZY, Tang QZ, 2016 Icariin protects H9c2 cardiomyocytes from lipopolysaccharide induced injury via inhibition of the reactive oxygen species dependent c Jun N terminal kinases/nuclear factor-κB pathway, Zhou H, Yuan Y, Liu Y, Ni J, Deng W, Bian ZY, Dai J, Tang QZ, 2015 Soluble ST2 may possess special superiority as a risk predictor in heart failure patients, Zhou H, Ni J, Yuan Y, Deng W, Bian ZY, Tang QZ, 2015 ATF3 regulates multiple targets and may play a dual role in cardiac hypertrophy and injury, Zhou H, Guo H, Zong J, Dai J, Yuan Y, Bian ZY, Tang QZ, 2014 Icariin attenuates angiotensin II-induced hypertrophy and apoptosis in H9c2 cardiomyocytes by inhibiting reactive oxygen species-dependent JNK and p38 pathways, Zhou H, Yuan Y, Liu Y, Deng W, Zong J, Bian ZY, Dai J, Tang QZ, 2014 Interferon regulatory factor 7 functions as a novel negative regulator of pathological cardiac hypertrophy, Jiang DS, Liu Y, Zhou H, Zhang Y, Zhang XD, Zhang XF, Chen K, Gao L, Peng J, Gong H, Chen Y, Yang Q, Liu PP, Fan GC, Zou Y, Li H, 2014 Paeoniflorin attenuates pressure overload-induced cardiac remodeling via inhibition of TGFβ/Smads and NF-κB pathways, Zhou H, Yang HX, Yuan Y, Deng W, Zhang JY, Bian ZY, Zong J, Dai J, Tang QZ, 2013 Stem cell antigen 1 protects against cardiac hypertrophy and fibrosis after pressure overload, Zhou H, Bian ZY, Zong J, Deng W, Yan L, Shen DF, Guo H, Dai J, Yuan Y, Zhang R, Lin YF, Hu X, Li H, Tang QZ, 2012 Activating transcription factor 3 deficiency promotes cardiac hypertrophy, dysfunction, and fibrosis induced by pressure overload, Zhou H, Shen DF, Bian ZY, Zong J, Deng W, Zhang Y, Guo YY, Li H, Tang QZ, 2011

Areas of Focus

Cardiac remodeling
Heart failure

Publications

TMEM173 protects against pressure overload-induced cardiac hypertrophy by modulating autophagy, Jin YG, Zhou H, Fan D, Che Y, Wang ZP, Wang SS, Tang QZ, 2020
Leukocyte immunoglobulin-like receptor B4 protects against cardiac hypertrophy via SHP-2-dependent inhibition of the NF-κB pathway, Zhou H, Li N, Yuan Y, Jin YG, Wu Q, Yan L, Bian ZY, Deng W, Shen DF, Li H, Tang QZ, 2020
STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3, Li N, Zhou H, Wu H, Wu Q, Duan M, Deng W, Tang Q, 2019
Andrographolide Protects against HG-Induced Inflammation, Apoptosis, Migration, and Impairment of Angiogenesis via PI3K/AKT-eNOS Signalling in HUVECs, Duan MX, Zhou H, Wu QQ, Liu C, Xiao Y, Deng W, Tang QZ, 2019
Antioxidative Property and Molecular Mechanisms Underlying Geniposide-Mediated Therapeutic Effects in Diabetes Mellitus and Cardiovascular Disease, Li N, Li L, Wu H, Zhou H, 2019
Geniposide Alleviates Isoproterenol-Induced Cardiac Fibrosis Partially via SIRT1 Activation in vivo and in vitro, Li N, Zhou H, Ma ZG, Zhu JX, Liu C, Song P, Kong CY, Wu HM, Deng W, Tang QZ, 2018
Activating transcription factor 3 in cardiovascular diseases: a potential therapeutic target, Zhou H, Li N, Yuan Y, Jin YG, Guo H, Deng W, Tang QZ, 2018
miR-133: A Suppressor of Cardiac Remodeling?, Li N, Zhou H, Tang Q, 2018
Red Blood Cell Distribution Width: A Novel Predictive Indicator for Cardiovascular and Cerebrovascular Diseases, Li N, Zhou H, Tang Q, 2017
Puerarin attenuates the inflammatory response and apoptosis in LPS-stimulated cardiomyocytes, Yuan Y, Zhou H, Wu QQ, Li FF, Bian ZY, Deng W, Zhou MQ, Tang QZ, 2016
Pleiotropic and puzzling effects of ATF3 in maladaptive cardiac remodeling, Zhou H, Yuan Y, Ni J, Guo H, Deng W, Bian ZY, Tang QZ, 2016
Icariin protects H9c2 cardiomyocytes from lipopolysaccharide induced injury via inhibition of the reactive oxygen species dependent c Jun N terminal kinases/nuclear factor-κB pathway, Zhou H, Yuan Y, Liu Y, Ni J, Deng W, Bian ZY, Dai J, Tang QZ, 2015
Soluble ST2 may possess special superiority as a risk predictor in heart failure patients, Zhou H, Ni J, Yuan Y, Deng W, Bian ZY, Tang QZ, 2015
ATF3 regulates multiple targets and may play a dual role in cardiac hypertrophy and injury, Zhou H, Guo H, Zong J, Dai J, Yuan Y, Bian ZY, Tang QZ, 2014
Icariin attenuates angiotensin II-induced hypertrophy and apoptosis in H9c2 cardiomyocytes by inhibiting reactive oxygen species-dependent JNK and p38 pathways, Zhou H, Yuan Y, Liu Y, Deng W, Zong J, Bian ZY, Dai J, Tang QZ, 2014
Interferon regulatory factor 7 functions as a novel negative regulator of pathological cardiac hypertrophy, Jiang DS, Liu Y, Zhou H, Zhang Y, Zhang XD, Zhang XF, Chen K, Gao L, Peng J, Gong H, Chen Y, Yang Q, Liu PP, Fan GC, Zou Y, Li H, 2014
Paeoniflorin attenuates pressure overload-induced cardiac remodeling via inhibition of TGFβ/Smads and NF-κB pathways, Zhou H, Yang HX, Yuan Y, Deng W, Zhang JY, Bian ZY, Zong J, Dai J, Tang QZ, 2013
Stem cell antigen 1 protects against cardiac hypertrophy and fibrosis after pressure overload, Zhou H, Bian ZY, Zong J, Deng W, Yan L, Shen DF, Guo H, Dai J, Yuan Y, Zhang R, Lin YF, Hu X, Li H, Tang QZ, 2012
Activating transcription factor 3 deficiency promotes cardiac hypertrophy, dysfunction, and fibrosis induced by pressure overload, Zhou H, Shen DF, Bian ZY, Zong J, Deng W, Zhang Y, Guo YY, Li H, Tang QZ, 2011

Cardiac Remodeling Heart Failure Mechanism Clinical Prevention Treatment Research Cardiovascular

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