Professor | Kai Dai | Asia Growth Partners

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Name	Kai Dai
Contact Information	daikai@whu.edu.cn
Language ability	English, Chinese
Province	Hubei

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Name

Kai Dai

Contact Information

daikai@whu.edu.cn

Language ability

English, Chinese

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Medical School
Academic Background & Achievements	1996-2001 Bachelor of Clinical Medicine: Wuhan University 2001-2004 Master of Internal Medicine: Tongji Medical College, Huazhong University of Science and Technology 2004-2007 PhD in Internal Medicine: Tongji Medical College, Huazhong University of Science and Technology Recent grants: National Natural Science Foundation of China, Tianqing Liver Disease Research Fund, Hubei Provincial Natural Science Foundation
Work Experience	2007.07-2007.11 Resident Physician, Department of Infectious Diseases, Renmin Hospital of Wuhan University 2007.11-2015.11 Attending Physician, Department of Infectious Diseases, Renmin Hospital of Wuhan University 2015.11-2020.11 Deputy Chief Physician, Department of Infectious Diseases, Renmin Hospital of Wuhan University 2020.11-present Chief Physician, Associate Professor, Department of Infectious Diseases, Renmin Hospital of Wuhan University
Awards	2017 Second Prize: Tianqing Liver Disease Research Fund for the study on the role of adiponectin in the tumor inflammatory microenvironment in liver cancer

University/Lab Affiliation and Title

Wuhan University

Faculty

Medical School

Academic Background & Achievements

1996-2001 Bachelor of Clinical Medicine: Wuhan University
2001-2004 Master of Internal Medicine: Tongji Medical College, Huazhong University of Science and Technology
2004-2007 PhD in Internal Medicine: Tongji Medical College, Huazhong University of Science and Technology
Recent grants: National Natural Science Foundation of China, Tianqing Liver Disease Research Fund, Hubei Provincial Natural Science Foundation

Work Experience

2007.07-2007.11 Resident Physician, Department of Infectious Diseases, Renmin Hospital of Wuhan University
2007.11-2015.11 Attending Physician, Department of Infectious Diseases, Renmin Hospital of Wuhan University
2015.11-2020.11 Deputy Chief Physician, Department of Infectious Diseases, Renmin Hospital of Wuhan University
2020.11-present Chief Physician, Associate Professor, Department of Infectious Diseases, Renmin Hospital of Wuhan University

Awards

2017 Second Prize: Tianqing Liver Disease Research Fund for the study on the role of adiponectin in the tumor inflammatory microenvironment in liver cancer

Areas of Focus	Chronic liver diseases Infectious diseases
Publications	Roles of autotaxin/autotaxin-lysophosphatidic acid axis in the initiation and progression of liver cancer, She S, Zhang Q, Shi JZ, Yang F, Dai K, 2022 Differential expression of insulin-like growth factor type 1 receptor identifies heterogeneous intrahepatic regulatory T subsets in mouse hepatocellular carcinoma, Huang YB, Huang L, Zhu JL, Wu Y, Shi JZ, Dai K, 2022 Advancement of chimeric antigen receptor-natural killer cells targeting hepatocellular carcinoma, Dai K, Wu Y, She S, Zhang Q, 2021 Leucine rich repeats and calponin homology domain containing 1 inhibits NK-92 cell cytotoxicity through attenuating Src signaling, Dai K, Chen ZB, She S, Shi JZ, Zhu JL, Huang YB, 2020 Kbtbd2 inhibits the cytotoxic activity of immortalized NK cells through down-regulating mTOR signaling in a mouse hepatocellular carcinoma model, Dai K, Huang YB, Chen ZB, Sun XM, Yang LH, Jiang YA, 2018 1810011o10 Rik Inhibits the Antitumor Effect of Intratumoral CD8+ T Cells through Suppression of Notch2 Pathway in a Murine Hepatocellular Carcinoma Model, Dai K, Huang L, Huang YB, Chen ZB, Yang LH, Jiang YA, 2017 Hepatic CD206-positive macrophages express amphiregulin to promote the immunosuppressive activity of regulatory T cells in HBV infection, Dai K, Huang L, Sun X, Yang L, Gong Z, 2015 Amphiregulin promotes the immunosuppressive activity of intrahepatic CD4+ regulatory T cells to impair CD8+ T-cell immunity against hepatitis B virus infection, Dai K, Huang L, Chen J, Yang L, Gong Z, 2015 Analysis of the risk factors of the prognosis for the mortality of 107 severe patients with COVID-19 in Wuhan, Dai K, Bao AY, Ye P, Xu M, Zhang QR, Zhou Y, Jiang WL, Jiang WB, Wang HM, Zhu MF, Tang LL, Zhu CL, Xia YC, Jiang YA, Zou XF, Li LJ, 2020 Analysis of G to A hypermutation of HBV in chronic hepatitis B patients, Dai K, Wang LW, Liu YH, Gong ZJ, 2010

Areas of Focus

Chronic liver diseases
Infectious diseases

Publications

Roles of autotaxin/autotaxin-lysophosphatidic acid axis in the initiation and progression of liver cancer, She S, Zhang Q, Shi JZ, Yang F, Dai K, 2022
Differential expression of insulin-like growth factor type 1 receptor identifies heterogeneous intrahepatic regulatory T subsets in mouse hepatocellular carcinoma, Huang YB, Huang L, Zhu JL, Wu Y, Shi JZ, Dai K, 2022
Advancement of chimeric antigen receptor-natural killer cells targeting hepatocellular carcinoma, Dai K, Wu Y, She S, Zhang Q, 2021
Leucine rich repeats and calponin homology domain containing 1 inhibits NK-92 cell cytotoxicity through attenuating Src signaling, Dai K, Chen ZB, She S, Shi JZ, Zhu JL, Huang YB, 2020
Kbtbd2 inhibits the cytotoxic activity of immortalized NK cells through down-regulating mTOR signaling in a mouse hepatocellular carcinoma model, Dai K, Huang YB, Chen ZB, Sun XM, Yang LH, Jiang YA, 2018
1810011o10 Rik Inhibits the Antitumor Effect of Intratumoral CD8+ T Cells through Suppression of Notch2 Pathway in a Murine Hepatocellular Carcinoma Model, Dai K, Huang L, Huang YB, Chen ZB, Yang LH, Jiang YA, 2017
Hepatic CD206-positive macrophages express amphiregulin to promote the immunosuppressive activity of regulatory T cells in HBV infection, Dai K, Huang L, Sun X, Yang L, Gong Z, 2015
Amphiregulin promotes the immunosuppressive activity of intrahepatic CD4+ regulatory T cells to impair CD8+ T-cell immunity against hepatitis B virus infection, Dai K, Huang L, Chen J, Yang L, Gong Z, 2015
Analysis of the risk factors of the prognosis for the mortality of 107 severe patients with COVID-19 in Wuhan, Dai K, Bao AY, Ye P, Xu M, Zhang QR, Zhou Y, Jiang WL, Jiang WB, Wang HM, Zhu MF, Tang LL, Zhu CL, Xia YC, Jiang YA, Zou XF, Li LJ, 2020
Analysis of G to A hypermutation of HBV in chronic hepatitis B patients, Dai K, Wang LW, Liu YH, Gong ZJ, 2010

Liver Cancer Hepatitis Cirrhosis Immunology Viral Infections Bacterial Infections Clinical Research Liver Disease Inflammation Treatment

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