Areas of Focus
- Pathogenesis of osteoarthritis
- Diagnosis and treatment of bone tumors
Work Experience
- 2010.7-2011.12 Resident Physician, Orthopedics, Renmin Hospital, Wuhan University
- 2011.12-2015.12 Attending Physician, Orthopedics, Renmin Hospital, Wuhan University
- 2015.10-2015.12 Technical Advisor, Traditional Chinese Medicine Hospital, Gushi County, Henan Province
- 2015.12-2016.8 Deputy Chief Physician, Orthopedics, Renmin Hospital, Wuhan University
- 2016.8-2019.6 Vice President, Songzi Hospital, Wuhan University
- 2019.6-2022.12 Deputy Director, Joint Surgery, Orthopedics, Renmin Hospital, Wuhan University
- 2022.4-2022.6 Team Leader, Second Medical Aid Team to Shanghai, Renmin Hospital, Wuhan University
- 2022.9-present Head of Epidemic Prevention and Control Command, Renmin Hospital, Wuhan University
- 2022.12-present Deputy Director, Chief Physician, Joint Surgery, Orthopedics, Renmin Hospital, Wuhan University
Academic Background & Achievements
- 2000.09-2005.06 Bachelor of Clinical Medicine, Wuhan University
- 2005.09-2007.06 Master of Surgery, Wuhan University
- 2007.09-2010.06 PhD in Surgery, Wuhan University
- Participated in 5 National Natural Science Foundation projects
- Received 4 national patents
- Won 1 Hubei Science and Technology Progress Award
Publications
- Gambogenic acid induces cell death in human osteosarcoma through altering iron metabolism, disturbing the redox balance, and activating the P53 signaling pathway, Jian-Lin Zhou, 2023
- CircSPI1_005 ameliorates osteoarthritis by sponging miR-370-3p to regulate the expression of MAP3K9, Jian-Lin Zhou, 2022
- Glucocorticoids induce osteonecrosis of the femoral head in rats via PI3K/AKT/FOXO1 signaling pathway, Jian-Lin Zhou, 2022
- Dexamethasone induces ferroptosis via P53/SLC7A11/GPX4 pathway in glucocorticoid-induced osteonecrosis of the femoral head, Jian-Lin Zhou, 2022
- Circular RNA circANKRD36 regulates Casz1 by targeting miR-599 to prevent osteoarthritis chondrocyte apoptosis and inflammation, Jian-Lin Zhou, 2021
- Identification of Disease-Specific Hub Biomarkers and Immune Infiltration in Osteoarthritis and Rheumatoid Arthritis Synovial Tissues by Bioinformatics Analysis, Jian-Lin Zhou, 2021
- Protective Effect of Human Umbilical Cord Mesenchymal Stem Cells in Glucocorticoid-induced Osteonecrosis of Femoral Head, Jian-Lin Zhou, 2021
- MicroRNA-21 Contributes to Acute Liver Injury in LPS-Induced Sepsis Mice by Inhibiting PPARα Expression, Jian-Lin Zhou, 2020
- Hsa-let-7g promotes osteosarcoma by reducing HOXB1 to activate NF-kB pathway, Jian-Lin Zhou, 2019
- Local intraarticular injection of vascular endothelial growth factor accelerates articular cartilage degeneration in rat osteoarthritis model, Jian-Lin Zhou, 2018
- The Relationship between HIF-2a and VEGF with Radiographic Severity in the Primary Osteoarthritic Knee, Jian-Lin Zhou, 2016
- PKCa Agonists Enhance the Protective Effect of Hyaluronic Acid on Nitric Oxide-Induced Apoptosis of Articular Chondrocytes in Vitro, Jian-Lin Zhou, 2013
- Hyaluronic Acid Inhibits Nitric Oxide-induced Apoptosis and Dedifferentiation of Articular Chondrocytes in Vitro, Jian-Lin Zhou, 2010
- Effects of hyaluronan on vascular endothelial growth factor and receptor-2 expression in a rabbit osteoarthritis model, Jian-Lin Zhou, 2009
- The protective effect of sodium hyaluronate on the cartilage of rabbit osteoarthritis by inhibiting Peroxisome Proliferator-Activated Receptor-Gamma mRNA expression, Jian-Lin Zhou, 2009
Awards
- 2019 Hubei Province Science and Technology Progress Second Prize: Mechanism of onset of femoral head necrosis and key technologies for rapid rehabilitation