Professor | Jian-Lin Zhou | Asia Growth Partners

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Name	Jian-Lin Zhou
Contact Information	13659880625
Language ability	Chinese, English
Province	Hubei

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Name

Jian-Lin Zhou

Contact Information

13659880625

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Medical School
Academic Background & Achievements	2000.09-2005.06 Bachelor of Clinical Medicine, Wuhan University 2005.09-2007.06 Master of Surgery, Wuhan University 2007.09-2010.06 PhD in Surgery, Wuhan University Participated in 5 National Natural Science Foundation projects Received 4 national patents Won 1 Hubei Science and Technology Progress Award
Work Experience	2010.7-2011.12 Resident Physician, Orthopedics, Renmin Hospital, Wuhan University 2011.12-2015.12 Attending Physician, Orthopedics, Renmin Hospital, Wuhan University 2015.10-2015.12 Technical Advisor, Traditional Chinese Medicine Hospital, Gushi County, Henan Province 2015.12-2016.8 Deputy Chief Physician, Orthopedics, Renmin Hospital, Wuhan University 2016.8-2019.6 Vice President, Songzi Hospital, Wuhan University 2019.6-2022.12 Deputy Director, Joint Surgery, Orthopedics, Renmin Hospital, Wuhan University 2022.4-2022.6 Team Leader, Second Medical Aid Team to Shanghai, Renmin Hospital, Wuhan University 2022.9-present Head of Epidemic Prevention and Control Command, Renmin Hospital, Wuhan University 2022.12-present Deputy Director, Chief Physician, Joint Surgery, Orthopedics, Renmin Hospital, Wuhan University
Awards	2019 Hubei Province Science and Technology Progress Second Prize: Mechanism of onset of femoral head necrosis and key technologies for rapid rehabilitation

University/Lab Affiliation and Title

Wuhan University

Faculty

Medical School

Academic Background & Achievements

2000.09-2005.06 Bachelor of Clinical Medicine, Wuhan University
2005.09-2007.06 Master of Surgery, Wuhan University
2007.09-2010.06 PhD in Surgery, Wuhan University
Participated in 5 National Natural Science Foundation projects
Received 4 national patents
Won 1 Hubei Science and Technology Progress Award

Work Experience

2010.7-2011.12 Resident Physician, Orthopedics, Renmin Hospital, Wuhan University
2011.12-2015.12 Attending Physician, Orthopedics, Renmin Hospital, Wuhan University
2015.10-2015.12 Technical Advisor, Traditional Chinese Medicine Hospital, Gushi County, Henan Province
2015.12-2016.8 Deputy Chief Physician, Orthopedics, Renmin Hospital, Wuhan University
2016.8-2019.6 Vice President, Songzi Hospital, Wuhan University
2019.6-2022.12 Deputy Director, Joint Surgery, Orthopedics, Renmin Hospital, Wuhan University
2022.4-2022.6 Team Leader, Second Medical Aid Team to Shanghai, Renmin Hospital, Wuhan University
2022.9-present Head of Epidemic Prevention and Control Command, Renmin Hospital, Wuhan University
2022.12-present Deputy Director, Chief Physician, Joint Surgery, Orthopedics, Renmin Hospital, Wuhan University

Awards

2019 Hubei Province Science and Technology Progress Second Prize: Mechanism of onset of femoral head necrosis and key technologies for rapid rehabilitation

Areas of Focus	Pathogenesis of osteoarthritis Diagnosis and treatment of bone tumors
Publications	Gambogenic acid induces cell death in human osteosarcoma through altering iron metabolism, disturbing the redox balance, and activating the P53 signaling pathway, Jian-Lin Zhou, 2023 CircSPI1_005 ameliorates osteoarthritis by sponging miR-370-3p to regulate the expression of MAP3K9, Jian-Lin Zhou, 2022 Glucocorticoids induce osteonecrosis of the femoral head in rats via PI3K/AKT/FOXO1 signaling pathway, Jian-Lin Zhou, 2022 Dexamethasone induces ferroptosis via P53/SLC7A11/GPX4 pathway in glucocorticoid-induced osteonecrosis of the femoral head, Jian-Lin Zhou, 2022 Circular RNA circANKRD36 regulates Casz1 by targeting miR-599 to prevent osteoarthritis chondrocyte apoptosis and inflammation, Jian-Lin Zhou, 2021 Identification of Disease-Specific Hub Biomarkers and Immune Infiltration in Osteoarthritis and Rheumatoid Arthritis Synovial Tissues by Bioinformatics Analysis, Jian-Lin Zhou, 2021 Protective Effect of Human Umbilical Cord Mesenchymal Stem Cells in Glucocorticoid-induced Osteonecrosis of Femoral Head, Jian-Lin Zhou, 2021 MicroRNA-21 Contributes to Acute Liver Injury in LPS-Induced Sepsis Mice by Inhibiting PPARα Expression, Jian-Lin Zhou, 2020 Hsa-let-7g promotes osteosarcoma by reducing HOXB1 to activate NF-kB pathway, Jian-Lin Zhou, 2019 Local intraarticular injection of vascular endothelial growth factor accelerates articular cartilage degeneration in rat osteoarthritis model, Jian-Lin Zhou, 2018 The Relationship between HIF-2a and VEGF with Radiographic Severity in the Primary Osteoarthritic Knee, Jian-Lin Zhou, 2016 PKCa Agonists Enhance the Protective Effect of Hyaluronic Acid on Nitric Oxide-Induced Apoptosis of Articular Chondrocytes in Vitro, Jian-Lin Zhou, 2013 Hyaluronic Acid Inhibits Nitric Oxide-induced Apoptosis and Dedifferentiation of Articular Chondrocytes in Vitro, Jian-Lin Zhou, 2010 Effects of hyaluronan on vascular endothelial growth factor and receptor-2 expression in a rabbit osteoarthritis model, Jian-Lin Zhou, 2009 The protective effect of sodium hyaluronate on the cartilage of rabbit osteoarthritis by inhibiting Peroxisome Proliferator-Activated Receptor-Gamma mRNA expression, Jian-Lin Zhou, 2009

Areas of Focus

Pathogenesis of osteoarthritis
Diagnosis and treatment of bone tumors

Publications

Gambogenic acid induces cell death in human osteosarcoma through altering iron metabolism, disturbing the redox balance, and activating the P53 signaling pathway, Jian-Lin Zhou, 2023
CircSPI1_005 ameliorates osteoarthritis by sponging miR-370-3p to regulate the expression of MAP3K9, Jian-Lin Zhou, 2022
Glucocorticoids induce osteonecrosis of the femoral head in rats via PI3K/AKT/FOXO1 signaling pathway, Jian-Lin Zhou, 2022
Dexamethasone induces ferroptosis via P53/SLC7A11/GPX4 pathway in glucocorticoid-induced osteonecrosis of the femoral head, Jian-Lin Zhou, 2022
Circular RNA circANKRD36 regulates Casz1 by targeting miR-599 to prevent osteoarthritis chondrocyte apoptosis and inflammation, Jian-Lin Zhou, 2021
Identification of Disease-Specific Hub Biomarkers and Immune Infiltration in Osteoarthritis and Rheumatoid Arthritis Synovial Tissues by Bioinformatics Analysis, Jian-Lin Zhou, 2021
Protective Effect of Human Umbilical Cord Mesenchymal Stem Cells in Glucocorticoid-induced Osteonecrosis of Femoral Head, Jian-Lin Zhou, 2021
MicroRNA-21 Contributes to Acute Liver Injury in LPS-Induced Sepsis Mice by Inhibiting PPARα Expression, Jian-Lin Zhou, 2020
Hsa-let-7g promotes osteosarcoma by reducing HOXB1 to activate NF-kB pathway, Jian-Lin Zhou, 2019
Local intraarticular injection of vascular endothelial growth factor accelerates articular cartilage degeneration in rat osteoarthritis model, Jian-Lin Zhou, 2018
The Relationship between HIF-2a and VEGF with Radiographic Severity in the Primary Osteoarthritic Knee, Jian-Lin Zhou, 2016
PKCa Agonists Enhance the Protective Effect of Hyaluronic Acid on Nitric Oxide-Induced Apoptosis of Articular Chondrocytes in Vitro, Jian-Lin Zhou, 2013
Hyaluronic Acid Inhibits Nitric Oxide-induced Apoptosis and Dedifferentiation of Articular Chondrocytes in Vitro, Jian-Lin Zhou, 2010
Effects of hyaluronan on vascular endothelial growth factor and receptor-2 expression in a rabbit osteoarthritis model, Jian-Lin Zhou, 2009
The protective effect of sodium hyaluronate on the cartilage of rabbit osteoarthritis by inhibiting Peroxisome Proliferator-Activated Receptor-Gamma mRNA expression, Jian-Lin Zhou, 2009

Osteoarthritis Pathogenesis Bone Tumors Diagnosis Treatment Surgery Joint Replacement Minimally Invasive Rehabilitation

Zhu Shaobo - Wuhan University

Bin Ren - Wuhan University

Xuejiao Sun - Wuhan University

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