Professor | Zhiwei Wang | Asia Growth Partners

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Name	Zhiwei Wang
Contact Information	wangzhiwei@whu.edu.cn
Language ability	Chinese, English
Province	Hubei

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Name

Zhiwei Wang

Contact Information

wangzhiwei@whu.edu.cn

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Medical School
Academic Background & Achievements	1979.9-1984.7 Bachelor's Degree: Tongji Medical College 1990.9-1993.7 Master's Degree: Wuhan University Medical School, Cardiothoracic Surgery 2001.9-2004.7 PhD: Huazhong University of Science and Technology, Cardiovascular Surgery Supervised 55 master students and 20 doctoral students
Work Experience	1984.8-1990.8 Resident, Cardiothoracic Surgery, Hubei Xiangfan Central Hospital 1993.9-1997.9 Attending Physician, Cardiothoracic Surgery, Renmin Hospital, Wuhan University 1997.10-2003.10 Associate Professor and Vice Chief Physician, Cardiothoracic Surgery, Renmin Hospital, Wuhan University 2003.11-present Chief Physician and Professor, Cardiothoracic Surgery, Renmin Hospital, Wuhan University 2004.6-present Deputy Director and Head of Cardiovascular Surgery Research Lab, Medical School, Wuhan University 2005.2-present Director of Cardiovascular Surgery, Renmin Hospital, Wuhan University 2009.3-present Director of Thoracic and Cardiovascular Surgery, Renmin Hospital, Wuhan University
Awards	2019 Ministry of Education Science and Technology Progress Award First Prize: Key technology system creation and application in heart transplantation 2015 Hubei Province Science and Technology Progress Award First Prize: Innovation in surgical techniques for complex ascending aorta and aortic arch diseases 2019 Hubei Province Science and Technology Achievement Promotion Award Second Prize: Clinical promotion and application of innovative surgical techniques for complex ascending aorta and aortic arch diseases 2015 Wuhan Science and Technology Progress Award First Prize: Innovation in surgical techniques for complex ascending aorta and aortic arch diseases 2010 Wuhan Science and Technology Progress Award Third Prize: Series of studies on brain protection during deep hypothermic circulatory arrest 2007 Hubei Province Science and Technology Progress Award Second Prize: Clinical research and application of minimally invasive coronary artery bypass grafting

University/Lab Affiliation and Title

Wuhan University

Faculty

Medical School

Academic Background & Achievements

1979.9-1984.7 Bachelor's Degree: Tongji Medical College
1990.9-1993.7 Master's Degree: Wuhan University Medical School, Cardiothoracic Surgery
2001.9-2004.7 PhD: Huazhong University of Science and Technology, Cardiovascular Surgery
Supervised 55 master students and 20 doctoral students

Work Experience

1984.8-1990.8 Resident, Cardiothoracic Surgery, Hubei Xiangfan Central Hospital
1993.9-1997.9 Attending Physician, Cardiothoracic Surgery, Renmin Hospital, Wuhan University
1997.10-2003.10 Associate Professor and Vice Chief Physician, Cardiothoracic Surgery, Renmin Hospital, Wuhan University
2003.11-present Chief Physician and Professor, Cardiothoracic Surgery, Renmin Hospital, Wuhan University
2004.6-present Deputy Director and Head of Cardiovascular Surgery Research Lab, Medical School, Wuhan University
2005.2-present Director of Cardiovascular Surgery, Renmin Hospital, Wuhan University
2009.3-present Director of Thoracic and Cardiovascular Surgery, Renmin Hospital, Wuhan University

Awards

2019 Ministry of Education Science and Technology Progress Award First Prize: Key technology system creation and application in heart transplantation
2015 Hubei Province Science and Technology Progress Award First Prize: Innovation in surgical techniques for complex ascending aorta and aortic arch diseases
2019 Hubei Province Science and Technology Achievement Promotion Award Second Prize: Clinical promotion and application of innovative surgical techniques for complex ascending aorta and aortic arch diseases
2015 Wuhan Science and Technology Progress Award First Prize: Innovation in surgical techniques for complex ascending aorta and aortic arch diseases
2010 Wuhan Science and Technology Progress Award Third Prize: Series of studies on brain protection during deep hypothermic circulatory arrest
2007 Hubei Province Science and Technology Progress Award Second Prize: Clinical research and application of minimally invasive coronary artery bypass grafting

Areas of Focus	Surgical treatment of aortic diseases Basic and clinical study of heart transplantation Surgical treatment of coronary heart diseases
Publications	Epidemiologic and clinical characteristics of heart transplant recipients during the 2019 coronavirus outbreak in Wuhan, China: A descriptive survey report, Ren ZL, Hu R, Wang ZW, et al., 2020 Iron deficiency promotes aortic medial degeneration via destructing cytoskeleton of vascular smooth muscle cells, Li B, Wang Z, Hong J, et al., 2021 BOP1 Knockdown Attenuates Neointimal Hyperplasia by Activating p53 and Inhibiting Nascent Protein Synthesis, Jia F, Wu Q, Wang Z, et al., 2021 Application of prosthesis eversion method for ascending aorta replacement guarantees better clinical outcomes of type A acute aortic dissection surgery, Hu Z, Wang Z, Chang J, et al., 2021 Lnc-OIP5-AS1 exacerbates aorta wall injury during the development of aortic dissection through upregulating TUB via sponging miR-143-3p, Wang P, Wang Z, Zhang M, et al., 2021 Elephant trunk stent fenestration for acute type A aortic dissection, Yu A, Zhang M, Wang Z, et al., 2020 Exosomes from dendritic cells with Mettl3 gene knockdown prevent immune rejection in a mouse cardiac allograft model, Wu H, Xu Z, Wang Z, et al., 2020 Two Cases Treated by Different Strategies for Common Carotid Artery Dissection with Thrombosis Due to a Type A Aortic Dissection, Ren W, Shi F, Wang Z, et al., 2020 Dendritic cells with METTL3 gene knockdown exhibit immature properties and prolong allograft survival, Wu H, Xu Z, Wang Z, et al., 2020 The sympathetic transmitter norepinephrine inhibits VSMC proliferation induced by TGFβ by suppressing the expression of the TGFβ receptor ALK5 in aorta remodeling, Hu Z, Li B, Wang Z, et al., 2020 When Behcet's disease meets Stanford type A aortic dissection, heart transplantation is a reliable treatment, Ren W, Li B, Wang Z, et al., 2020 Avβ3 Single-Stranded DNA Aptamer Attenuates Vascular Smooth Muscle Cell Proliferation and Migration via Ras-PI3K/MAPK Pathway, Wu HB, Wang ZW, Shi F, et al., 2020 Painless retrograde type A aortic dissection followed conservative treatment of type B aortic dissection: a case report, Ruan Y, Wang Z, Wu Z, et al., 2020 Acute Aortic Dissection Surgery: Hybrid Debranching Versus Total Arch Replacement, Shi F, Wang Z, 2020 Avβ3 single-stranded DNA aptamer attenuates vascular restenosis via Ras-PI3K/MAPK pathway in rats after percutaneous transluminal coronary angioplasty, Wu HB, Wang ZW, Shi F, et al., 2020 IL-5 overexpression attenuates aortic dissection by reducing inflammation and smooth muscle cell apoptosis, Ren W, Wang Z, Wang J, et al., 2020 miR-200a Attenuated Doxorubicin-Induced Cardiotoxicity through Upregulation of Nrf2 in Mice, Hu X, Liu H, Wang Z, et al., 2019 Inhibition of CACNA1H attenuates doxorubicin-induced acute cardiotoxicity by affecting endoplasmic reticulum stress, Hu J, Wu Q, Wang Z, et al., 2019 Abnormal Ribosome Biogenesis Partly Induced p53-Dependent Aortic Medial Smooth Muscle Cell Apoptosis and Oxidative Stress, Wu Q, Hong J, Wang Z, et al., 2019 Up regulation of isoleucyl-tRNA synthetase promotes vascular smooth muscle cells dysfunction via p38 MAPK/PI3K signaling pathways, Li B, Wang Z, Chen R, et al., 2019

Areas of Focus

Surgical treatment of aortic diseases
Basic and clinical study of heart transplantation
Surgical treatment of coronary heart diseases

Publications

Epidemiologic and clinical characteristics of heart transplant recipients during the 2019 coronavirus outbreak in Wuhan, China: A descriptive survey report, Ren ZL, Hu R, Wang ZW, et al., 2020
Iron deficiency promotes aortic medial degeneration via destructing cytoskeleton of vascular smooth muscle cells, Li B, Wang Z, Hong J, et al., 2021
BOP1 Knockdown Attenuates Neointimal Hyperplasia by Activating p53 and Inhibiting Nascent Protein Synthesis, Jia F, Wu Q, Wang Z, et al., 2021
Application of prosthesis eversion method for ascending aorta replacement guarantees better clinical outcomes of type A acute aortic dissection surgery, Hu Z, Wang Z, Chang J, et al., 2021
Lnc-OIP5-AS1 exacerbates aorta wall injury during the development of aortic dissection through upregulating TUB via sponging miR-143-3p, Wang P, Wang Z, Zhang M, et al., 2021
Elephant trunk stent fenestration for acute type A aortic dissection, Yu A, Zhang M, Wang Z, et al., 2020
Exosomes from dendritic cells with Mettl3 gene knockdown prevent immune rejection in a mouse cardiac allograft model, Wu H, Xu Z, Wang Z, et al., 2020
Two Cases Treated by Different Strategies for Common Carotid Artery Dissection with Thrombosis Due to a Type A Aortic Dissection, Ren W, Shi F, Wang Z, et al., 2020
Dendritic cells with METTL3 gene knockdown exhibit immature properties and prolong allograft survival, Wu H, Xu Z, Wang Z, et al., 2020
The sympathetic transmitter norepinephrine inhibits VSMC proliferation induced by TGFβ by suppressing the expression of the TGFβ receptor ALK5 in aorta remodeling, Hu Z, Li B, Wang Z, et al., 2020
When Behcet's disease meets Stanford type A aortic dissection, heart transplantation is a reliable treatment, Ren W, Li B, Wang Z, et al., 2020
Avβ3 Single-Stranded DNA Aptamer Attenuates Vascular Smooth Muscle Cell Proliferation and Migration via Ras-PI3K/MAPK Pathway, Wu HB, Wang ZW, Shi F, et al., 2020
Painless retrograde type A aortic dissection followed conservative treatment of type B aortic dissection: a case report, Ruan Y, Wang Z, Wu Z, et al., 2020
Acute Aortic Dissection Surgery: Hybrid Debranching Versus Total Arch Replacement, Shi F, Wang Z, 2020
Avβ3 single-stranded DNA aptamer attenuates vascular restenosis via Ras-PI3K/MAPK pathway in rats after percutaneous transluminal coronary angioplasty, Wu HB, Wang ZW, Shi F, et al., 2020
IL-5 overexpression attenuates aortic dissection by reducing inflammation and smooth muscle cell apoptosis, Ren W, Wang Z, Wang J, et al., 2020
miR-200a Attenuated Doxorubicin-Induced Cardiotoxicity through Upregulation of Nrf2 in Mice, Hu X, Liu H, Wang Z, et al., 2019
Inhibition of CACNA1H attenuates doxorubicin-induced acute cardiotoxicity by affecting endoplasmic reticulum stress, Hu J, Wu Q, Wang Z, et al., 2019
Abnormal Ribosome Biogenesis Partly Induced p53-Dependent Aortic Medial Smooth Muscle Cell Apoptosis and Oxidative Stress, Wu Q, Hong J, Wang Z, et al., 2019
Up regulation of isoleucyl-tRNA synthetase promotes vascular smooth muscle cells dysfunction via p38 MAPK/PI3K signaling pathways, Li B, Wang Z, Chen R, et al., 2019

Aortic Surgery Heart Transplantation Coronary Artery Disease Surgical Techniques Clinical Research Vascular Surgery Cardiovascular Transplant Surgery Medical Innovation Patient Outcomes

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