Professor | Qianxue Chen | Asia Growth Partners

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Name	Qianxue Chen
Contact Information	chenqx666@whu.edu.cn
Language ability	English, Chinese
Province	Hubei

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Name

Qianxue Chen

Contact Information

chenqx666@whu.edu.cn

Language ability

English, Chinese

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Medical School
Academic Background & Achievements	1980.9-1985.7 Bachelor: Hubei Medical University, Medical Department 1985.9-1988.7 Master: Hubei Medical University, Neurology 2000.9-2003.12 PhD: Wuhan University, School of Medicine, Surgery
Work Experience	1988.7-1990.10 Wuhan University Renmin Hospital, Neurosurgery - Resident 1990.11-1997.9 Wuhan University Renmin Hospital, Neurosurgery - Attending Physician 1997.10-2001.10 Wuhan University Renmin Hospital, Neurosurgery - Associate Professor, Associate Chief Physician 2001.11-present Wuhan University Renmin Hospital, Neurosurgery - Chief Physician, Professor
Awards	2012 Wuchang Talent 2013 Hubei Province Government Medical Leadership Talent 2014 Hubei Province Science and Technology Innovation Source Engineering Innovation Entrepreneurship Talent Award 2014 Third Wuhan Health and Family Planning Commission 'My Favorite Doctor' 2017 Wang Zhongcheng China Neurosurgery Physician Annual Award 2019 Tenth Wuhan University 'My Favorite Mentor' 2020 State Council Government Special Allowance Personnel

University/Lab Affiliation and Title

Wuhan University

Faculty

Medical School

Academic Background & Achievements

1980.9-1985.7 Bachelor: Hubei Medical University, Medical Department
1985.9-1988.7 Master: Hubei Medical University, Neurology
2000.9-2003.12 PhD: Wuhan University, School of Medicine, Surgery

Work Experience

1988.7-1990.10 Wuhan University Renmin Hospital, Neurosurgery - Resident
1990.11-1997.9 Wuhan University Renmin Hospital, Neurosurgery - Attending Physician
1997.10-2001.10 Wuhan University Renmin Hospital, Neurosurgery - Associate Professor, Associate Chief Physician
2001.11-present Wuhan University Renmin Hospital, Neurosurgery - Chief Physician, Professor

Awards

2012 Wuchang Talent
2013 Hubei Province Government Medical Leadership Talent
2014 Hubei Province Science and Technology Innovation Source Engineering Innovation Entrepreneurship Talent Award
2014 Third Wuhan Health and Family Planning Commission 'My Favorite Doctor'
2017 Wang Zhongcheng China Neurosurgery Physician Annual Award
2019 Tenth Wuhan University 'My Favorite Mentor'
2020 State Council Government Special Allowance Personnel

Areas of Focus	Glioma - Basic and Clinical Studies Surgical Treatment of Epilepsy
Publications	TGF-β induces GBM mesenchymal transition through upregulation of CLDN4 and nuclear translocation to activate TNF-α/NF-κB signal pathway, Yan T, Tan Y, Deng G, Sun Z, Liu B, Wang Y, Yuan F, Sun Q, Hu P, Gao L, Tian D, Chen Q, 2022 The dual role of p62 in ferroptosis of glioblastoma according to p53 status, Yuan F, Sun Q, Zhang S, Ye L, Xu Y, Deng G, Xu Z, Zhang S, Liu B, Chen Q, 2022 Rho family GTPase 1 (RND1), a novel regulator of p53, enhances ferroptosis in glioblastoma, Sun Q, Xu Y, Yuan F, Qi Y, Wang Y, Chen Q, Liu B, 2022 Betulinic acid self-assembled nanoparticles for effective treatment of glioblastoma, Li Y, Wang Y, Gao L, Tan Y, Cai J, Ye Z, Chen AT, Xu Y, Zhao L, Tong S, Sun Q, Liu B, Zhang S, Tian D, Deng G, Zhou J, Chen Q, 2022 Hsa_circ_0072309 enhances autophagy and TMZ sensitivity in glioblastoma, Yuan F, Zhang S, Sun Q, Ye L, Xu Y, Xu Z, Deng G, Zhang S, Liu B, Chen Q, 2022 Fatostatin induces ferroptosis through inhibition of the AKT/mTORC1/GPX4 signaling pathway in glioblastoma, Cai J, Ye Z, Hu Y, Ye L, Gao L, Wang Y, Sun Q, Tong S, Zhang S, Wu L, Yang J, Chen Q, 2023 The RNA-binding protein CSTF2 regulates BAD to inhibit apoptosis in glioblastoma, Xu Y, Yuan F, Sun Q, Zhao L, Hong Y, Tong S, Qi Y, Ye L, Hu P, Ye Z, Zhang S, Liu B, Chen Q, 2023 C/EBPβ/AEP signaling couples atherosclerosis to the pathogenesis of Alzheimer's disease, Liao J, Chen G, Liu X, Wei ZZ, Yu SP, Chen Q, Ye K, 2022 Autocatalytic Delivery of Brain Tumor-targeting, Size-shrinkable Nanoparticles for Treatment of Breast Cancer Brain Metastases, Zhang S, Deng G, Liu F, Peng B, Bao Y, Du F, Chen AT, Liu J, Chen Z, Ma J, Tang X, Chen Q, Zhou J, 2020 Hypoxia induced ferritin light chain (FTL) promoted epithelia mesenchymal transition and chemoresistance of glioma, Liu J, Gao L, Zhan N, Xu P, Yang J, Yuan F, Xu Y, Cai Q, Geng R, Chen Q, 2020 Small GTPase RHOE/RND3, a new critical regulator of NF-κB signalling in glioblastoma multiforme?, Sun Q, Dong H, Li Y, Yuan F, Xu Y, Mao S, Xiong X, Chen Q, Liu B TIPE3 is a regulator of cell apoptosis in glioblastoma, Yuan F, Liu B, Xu Y, Li Y, Sun Q, Xu P, Geng R, Den G, Yang J, Zhang S, Gao L, Liao J, Liu J, Yang X, Tan Y, Chen Q, 2019 RND2 attenuates apoptosis and autophagy in glioblastoma cells by targeting the p38 MAPK signalling pathway, Xu Y, Sun Q, Yuan F, Dong H, Zhang H, Geng R, Qi Y, Xiong X, Chen Q, Liu B, 2020 An early neuroprotective effect of atorvastatin against subarachnoid hemorrhage, Chen JH, Wu T, Xia WY, Shi ZH, Zhang CL, Chen L, Chen QX, Wang YH, 2020 The Potential Value of Targeting Ferroptosis in Early Brain Injury After Acute CNS Disease, Chen J, Wang Y, Wu J, Yang J, Li M, Chen Q, 2020 Downregulation of RND3/RhoE in glioblastoma patients promotes tumorigenesis through augmentation of notch transcriptional complex activity, Liu B, Lin X, Yang X, Dong H, Yue X, Andrade KC, Guo Z, Yang J, Wu L, Zhu X, Zhang S, Tian D, Wang J, Cai Q, Chen Q, Mao S, Chen Q, Chang J, 2015

Areas of Focus

Glioma - Basic and Clinical Studies
Surgical Treatment of Epilepsy

Publications

TGF-β induces GBM mesenchymal transition through upregulation of CLDN4 and nuclear translocation to activate TNF-α/NF-κB signal pathway, Yan T, Tan Y, Deng G, Sun Z, Liu B, Wang Y, Yuan F, Sun Q, Hu P, Gao L, Tian D, Chen Q, 2022
The dual role of p62 in ferroptosis of glioblastoma according to p53 status, Yuan F, Sun Q, Zhang S, Ye L, Xu Y, Deng G, Xu Z, Zhang S, Liu B, Chen Q, 2022
Rho family GTPase 1 (RND1), a novel regulator of p53, enhances ferroptosis in glioblastoma, Sun Q, Xu Y, Yuan F, Qi Y, Wang Y, Chen Q, Liu B, 2022
Betulinic acid self-assembled nanoparticles for effective treatment of glioblastoma, Li Y, Wang Y, Gao L, Tan Y, Cai J, Ye Z, Chen AT, Xu Y, Zhao L, Tong S, Sun Q, Liu B, Zhang S, Tian D, Deng G, Zhou J, Chen Q, 2022
Hsa_circ_0072309 enhances autophagy and TMZ sensitivity in glioblastoma, Yuan F, Zhang S, Sun Q, Ye L, Xu Y, Xu Z, Deng G, Zhang S, Liu B, Chen Q, 2022
Fatostatin induces ferroptosis through inhibition of the AKT/mTORC1/GPX4 signaling pathway in glioblastoma, Cai J, Ye Z, Hu Y, Ye L, Gao L, Wang Y, Sun Q, Tong S, Zhang S, Wu L, Yang J, Chen Q, 2023
The RNA-binding protein CSTF2 regulates BAD to inhibit apoptosis in glioblastoma, Xu Y, Yuan F, Sun Q, Zhao L, Hong Y, Tong S, Qi Y, Ye L, Hu P, Ye Z, Zhang S, Liu B, Chen Q, 2023
C/EBPβ/AEP signaling couples atherosclerosis to the pathogenesis of Alzheimer's disease, Liao J, Chen G, Liu X, Wei ZZ, Yu SP, Chen Q, Ye K, 2022
Autocatalytic Delivery of Brain Tumor-targeting, Size-shrinkable Nanoparticles for Treatment of Breast Cancer Brain Metastases, Zhang S, Deng G, Liu F, Peng B, Bao Y, Du F, Chen AT, Liu J, Chen Z, Ma J, Tang X, Chen Q, Zhou J, 2020
Hypoxia induced ferritin light chain (FTL) promoted epithelia mesenchymal transition and chemoresistance of glioma, Liu J, Gao L, Zhan N, Xu P, Yang J, Yuan F, Xu Y, Cai Q, Geng R, Chen Q, 2020
Small GTPase RHOE/RND3, a new critical regulator of NF-κB signalling in glioblastoma multiforme?, Sun Q, Dong H, Li Y, Yuan F, Xu Y, Mao S, Xiong X, Chen Q, Liu B
TIPE3 is a regulator of cell apoptosis in glioblastoma, Yuan F, Liu B, Xu Y, Li Y, Sun Q, Xu P, Geng R, Den G, Yang J, Zhang S, Gao L, Liao J, Liu J, Yang X, Tan Y, Chen Q, 2019
RND2 attenuates apoptosis and autophagy in glioblastoma cells by targeting the p38 MAPK signalling pathway, Xu Y, Sun Q, Yuan F, Dong H, Zhang H, Geng R, Qi Y, Xiong X, Chen Q, Liu B, 2020
An early neuroprotective effect of atorvastatin against subarachnoid hemorrhage, Chen JH, Wu T, Xia WY, Shi ZH, Zhang CL, Chen L, Chen QX, Wang YH, 2020
The Potential Value of Targeting Ferroptosis in Early Brain Injury After Acute CNS Disease, Chen J, Wang Y, Wu J, Yang J, Li M, Chen Q, 2020
Downregulation of RND3/RhoE in glioblastoma patients promotes tumorigenesis through augmentation of notch transcriptional complex activity, Liu B, Lin X, Yang X, Dong H, Yue X, Andrade KC, Guo Z, Yang J, Wu L, Zhu X, Zhang S, Tian D, Wang J, Cai Q, Chen Q, Mao S, Chen Q, Chang J, 2015

Glioma Clinical Trials Neurosurgery Brain Tumors Surgical Intervention Treatment Standards Quality Control Consensus Development Guidelines China

Daofeng Tian - Wuhan University

Wei Yi - Wuhan University

Ma Chiyuan - Nanjing University

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