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Zhongyuan Xia
Medical School
Wuhan University
Hubei
Language: Chinese, English
Diabetes
Myocardial Ischemia
Reperfusion Injury
Perioperative Care
Organ Protection
Pharmacological Preconditioning
Postconditioning
Cardiomyopathy
Clinical Research
Anesthesiology
Areas of Focus
- Prevention and treatment of myocardial ischemia-reperfusion injury in diabetes
- Perioperative protection of vital organs
Work Experience
- 1988-1991 Resident Physician, Second Hospital affiliated to Hubei Medical University
- 1994-1996 Resident Physician, First Hospital affiliated to Hubei Medical University
- 1996-1999 Attending Physician, First Hospital affiliated to Hubei Medical University
- 1999-2004 Associate Chief Physician/Associate Professor, Renmin Hospital of Wuhan University
- 2004-2011 Chief Physician (Level 4), Renmin Hospital of Wuhan University
- 2005-2006 Visiting Scholar, University of British Columbia, Canada
- 2007-2017 Professor (Level 4), Renmin Hospital of Wuhan University
- 2011-2013 Deputy Chief Physician (Level 3), Renmin Hospital of Wuhan University
- 2013-present Chief Physician (Level 2), Renmin Hospital of Wuhan University
- 2019-present Professor (Level 2), Renmin Hospital of Wuhan University
Academic Background & Achievements
- 1983-1988 Bachelor's Degree in Clinical Medicine from Hubei Medical College
- 1991-1994 Master's Degree in Anesthesiology from Hubei Medical University
- 2002-2005 PhD in Surgery from Wuhan University
- Published over 300 articles, including 40 in peer-reviewed journals
- Owned 6 national patents
Publications
- Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection, Lei S, Jiang F, Su W, Chen C, Chen J, Mei W, Zhan LY, Jia Y, Zhang L, Liu D, Xia ZY, Xia Z, 2020
- Roles of HDAC3-orchestrated circadian clock gene oscillations in diabetic rats following myocardial ischaemia/reperfusion injury, Qiu Z, Ming H, Lei S, Zhou B, Zhao B, Yu Y, Xue R, Xia Z, 2021
- Ropivacaine-loaded, hydroxypropyl chitin thermo-sensitive hydrogel combined with hyaluronan: an injectable, sustained-release system for providing long-lasting local anesthesia in rats, Qiao Q, Fu X, Huang R, Lei S, Leng Y, Liu Z, Xia Z, Jiang X, 2022
- DJ-1 overexpression restores ischaemic post-conditioning-mediated cardioprotection in diabetic rats: role of autophagy, Zhou B, Lei S, Xue R, Leng Y, Xia Z, Xia ZY, 2017
- Ischemic post-conditioning attenuates acute lung injury induced by intestinal ischemia-reperfusion in mice: role of Nrf2, Meng QT, Cao C, Wu Y, Liu HM, Li W, Sun Q, Chen R, Xiao YG, Tang LH, Jiang Y, Leng Y, Lei SQ, Lee CC, Barry DM, Chen X, Xia ZY, 2016
- Selective Inhibition of PTEN Preserves Ischemic Postconditioning Cardioprotection in STZ- induced Type1 Diabetic Rats: Role of the PI3K/Akt and JAK2/STAT3 Pathways, Xue R, Lei S, Xia ZY, Wu Y, Meng Q, Zhan L, Su W, Liu H, Xu J, Liu Z, Zhou B, Xia Z, 2016
- Propofol Ameliorates Hyperglycemia-Induced Cardiac Hypertrophy and Dysfunction via Heme Oxygenase-1/Signal Transducer and Activator of Transcription 3 Signaling Pathway in Rats, Xu J, Li H, Irwin MG, Xia ZY, Mao X, Lei S, Wong GT, Hung V, Cheung CW, Fang X, Clanachan AS, Xia Z, 2014
Awards
- 2014 Second Grade Award of Science and Technology Progress, Hubei Province: Mechanisms and prevention of multi-organ damage caused by ischemia-reperfusion
- 2017 Second Grade Award of Science and Technology Progress, Hubei Province: Mechanisms and prevention of increased vulnerability to renal reperfusion injury in perioperative diabetic patients
- 2020 Second Grade Award of Science and Technology Promotion, Hubei Province: Clinical application of perioperative protection of vital organs in high-risk patients and critical surgeries
