1991-1996 Bachelor of Clinical Medicine: Shanxi Medical University
2002-2005 Master of Internal Medicine: Zhejiang University
2006-2012 PhD in Immunology: Zhejiang University (Joint PhD with Stanford University)
Funded by National Natural Science Foundation (5 items), Hubei Provincial Natural Science Foundation (1 item)
Published nearly 80 papers, including 69 SCI papers
1996-2002 Resident and Attending Physician, Neurology Department, First People's Hospital of Yangquan City, Shanxi Province
2009-2012 Joint PhD and Research Assistant, Department of Neurosurgery, Stanford University School of Medicine
2012-2014 Lecturer, Department of Pathology, Hangzhou Normal University Medical School
2014-present Associate Professor and Professor, Central Laboratory, Renmin Hospital, Wuhan University
2020 Third Prize for Scientific and Technological Progress of Hubei Province: Mechanism and Prevention of Ischemic Brain Injury and Immune Regulation
Research
Pathogenesis of cerebral ischemia Effects of cerebral ischemia on the immune system
Cuproptosis facilitates immune activation but promotes immune escape and a machine learning-based Cuproptosis-related signature is identified for predicting prognosis and immunotherapy response of gliomas, Feng S, Zhang YG, Zhu H, Jian ZH, Zeng Z, Ye YZ, Li YN, Smerin D, Zhang X, Zou N, Gu LJ, Xiong XX, 2023
Bibliometric and visualization analysis of matrix metalloproteinases in ischemic stroke from 1992 to 2022, Li YN, Gao YK, Feng S, Gu LJ, 2023
Trends in NLRP3 Inflammasome research in ischemic stroke from 2011 to 2022: A bibliometric analysis, Zhu H, Zhang YG, Feng S, Li YN, Ye YZ, Jian ZH, Xiong XX, Gu LJ, 2023
CTRP6 alleviates cerebral ischemia-reperfusion injury in diabetic mice via activating Sirt1 signaling pathway, Zhao B, Li M, Li BY, Li YN, Shen QN, Hou JB, Wu Y, Gu LJ, Gao WW, 2023
ATG5 Knockdown Attenuates Ischemia‒Reperfusion Injury by Reducing Excessive Autophagy-Induced Ferroptosis, Zhu H, Zhong Y, Chen R, Wang L, Li YT, Jian ZH, Gu LJ, Xiong XX, 2022
NLRP3 inflammasome deficiency attenuates cerebral ischemia-reperfusion injury by inhibiting ferroptosis, Wang Z, Li YN, Ye YZ, Zhu H, Zhang J, Wang HJ, Lei JX, Gu LJ, Zhan LY, 2022
Different gender-derived gut microbiota influence stroke outcomes by mitigating inflammation, Wang JC, Zhong Y, Mahgoub OK, Jian ZH, Gu LJ, Xiong XX, 2022
An ultrasensitive fluorescent platform for monitoring GSH variation during ischemic stroke, Xiong XX, Ye YZ, Gao XY, Zhu H, Hu W, Li CY, Jian ZH, Deng HP, Gu LJ, 2022
Peripheral organs injury after stroke, Wang J, Zhang JH, Ye YZ, Xu QX, Li YN, Feng S, Xiong XX, Jian ZH, Gu LJ, 2022
JAK2/STAT3 Axis Intermediates Microglia/Macrophage Polarization During Cerebral Ischemia/Reperfusion Injury, Zhong Y, Gu LJ, Ye YZ, Zhu H, Pu B, Wang JC, Li YT, Qiu S, Jian ZH, Xiong XX, 2022
A second Near-Infrared Ru (II) Polypyridyl complex for synergistic chemo-photothermal therapy, Liu YS, Li QQ, Gu MJ, Lu DS, Xiong XX, Zhang ZY, Pan YN, Liao YQ, Ding QH, Gong WX, Chen SL, Guan MT, Wu JZ, Tian ZQ, Deng H, Gu LJ, Hong XC, Xiao YL, 2022
Pan-Cancer Analysis of PIMREG as a Biomarker for the Prognostic and Immunological Role, Zhu H, Hu XY, Ye YZ, Jian ZH, Zhong Y, Gu LJ, Xiong XX, 2021
Janus Kinase Inhibition Ameliorates Ischemic Stroke Injury and Neuroinflammation through Reducing NLRP3 Inflammasome Activation via JAK2/STAT3 Pathway Inhibition, Zhu H, Jian ZH, Zhong Y, Ye YZ, Zhang YG, Hu XY, Pu B, Gu LJ, Xiong XX, 2021
The bidirectional role of the JAK2/STAT3 signaling pathway and related mechanisms in cerebral ischemia-reperfusion injury, Zhong Y, Yin B, Ye YZ, Omar D, Xiong XX, Jian ZH, Gu LJ, 2021
Relevant mediators involved in and therapies targeting the inflammatory response induced by activation of the NLRP3 inflammasome in ischemic stroke, Xu QX, Zhao B, Ye YZ, Li YN, Zhang YG, Xiong XX, Gu LJ, 2021
Inflammation-mediated angiogenesis in ischemic stroke, Zhu H, Zhang YG, Zhong Y, Ye YZ, Hu XY, Xiong XX, Gu LJ, 2021
Sodium Tanshinone IIA Sulfonate protects against cerebral ischemia–reperfusion injury by inhibiting autophagy and inflammation, Wang L, Xiong XX, Zhang X, Ye YZ, Jian ZH, Gao WW, Gu LJ, 2020
Expression, location, clinical implication and bioinformatics analysis of RNASET2 in gastric adenocarcinoma, Zeng Z, Zhang X, Li D, Li Jin, Yuan JP, Gu LJ, Xiong XX, 2020
Targeting oxidative stress and inflammation to prevent ischemia-reperfusion injury, Wu LQ, Xiong XX, Wu XM, Ye YZ, Jian ZH, Zeng Z, Gu LJ, 2020
Meisoindigo protects against focal cerebral ischemia-reperfusion injury by inhibiting NLRP3 inflammasome activation and regulating microglia/macrophage polarization via TLR4/NF-κB signaling pathway, Ye YZ, Jin T, Zhang X, Zeng Z, Ye BX, Wang JC, Zhong Y, Xiong XX, Gu LJ, 2019
Glycyrrhizin protects against focal cerebral ischemia via inhibition of T cell activity and HMGB1-mediated mechanisms, Xiong XX, Gu LJ, Wang Y, Luo Y, Zhang HF, Lee J, Krams SM, Zhu SM, Zhao H, 2016
Moderate hypothermia inhibits brain inflammation and attenuates stroke-induced immunodepression in rats, Gu LJ, Xiong XX, Ito T, Lee J, Xu BH, Krams S, Steinberg GK, Zhao H, 2014
Distinctive effects of t cell subsets in neuronal injury induced by cocultured splenocytes in vitro and by in vivo stroke in mice, Gu LJ, Xiong XX, Zhang HF, Xu BH, Steinberg GK, Zhao H, 2012
