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Jieliang Chen
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, English, German
Hepatitis B Virus
Minichromosomes
Epigenetic Regulation
Interferon
Immune Modulation
Antiviral Drug Targets
Novel Therapeutic Strategies
Liver Diseases
Virology
Pathogen Biology
Areas of Focus
- Medical Virology
- Hepatology
- Immune Regulation
Work Experience
- 2024.03-present - Fudan University, School of Basic Medical Sciences, Deputy Director of Pathogen Biology Department
- 2016.05-present - Fudan University, School of Basic Medical Sciences, Assistant Researcher, Associate Professor, Researcher, Professor
- 2013.09-2016.04 - Fudan University, Postdoctoral Researcher, Biology Postdoctoral Mobile Station
- 2013.03-2013.05 - University of Duisburg-Essen, Medical School, Visiting Scholar
Academic Background & Achievements
- 2008.09—2013.06 Medical Doctor: Fudan University, School of Basic Medical Sciences, Pathogen Biology
- 2003.09—2008.06 Medical Bachelor: Fudan University, Shanghai Medical College, Basic Medicine
Publications
- Hepatitis B Virus cccDNA Minichromosomes in Distinct Epigenetic Transcriptional States Differ in Their Vulnerability to Damage, Wang, Y. et al., 2022
- Functional Comparison of Interferon-alpha Subtypes Reveals Potent Hepatitis B Virus Suppression by a Concerted Action of Interferon-alpha and Interferon-gamma Signaling, Chen, J. et al., 2021
- Hepatitis B virus sensitivity to interferon-alpha in hepatocytes is more associated with cellular interferon response than with viral genotype, Shen, F. et al., 2018
- PRMT5 restricts hepatitis B virus replication through epigenetic repression of covalently closed circular DNA transcription and interference with pregenomic RNA encapsidation, Zhang, W. et al., 2017
- Medical Microbiology, 2nd Edition, Editor, 2021
Awards
- 2021: 'One Health' Fund First Prize
- 2020: Fudan University Advanced Individual in Fighting COVID-19
- 2019: Shanghai Natural Science Award First Prize (Second Contributor)
- 2018: Fudan University Outstanding Postdoctoral Fellow
- 2017: Asia-Pacific Association for the Study of the Liver (APASL) Young Investigator Award
- 2015: Ministry of Education Natural Science Award First Prize (Third Contributor)
