Professor | Xiaoqing Gan | Asia Growth Partners

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Name	Xiaoqing Gan
Contact Information	nxiaoqinggan@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Xiaoqing Gan

Contact Information

nxiaoqinggan@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1992.09 - 1996.07 Bachelor's in Biochemistry: East China University of Science and Technology 1999.09 - 2001.12 Master's in Biochemistry and Molecular Biology: Shanghai Institute of Life Sciences, Chinese Academy of Sciences 2002.09 - 2008.05 Ph.D. in Biochemistry and Molecular Biology: Shanghai Institute of Life Sciences, Chinese Academy of Sciences
Work Experience	1996.07 - 1997.06 - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Research Intern 1997.07 - 2000.06 - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Research Assistant 2000.07 - 2000.04 - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Assistant Researcher 2008.05 - 2009.05 - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Associate Researcher 2009.05 - 2013.03 - Yale University School of Medicine - Postdoctoral Fellow 2013.06 - Present - Fudan University, School of Basic Medical Sciences, Department of Biochemistry and Molecular Biology - Researcher
Awards	2014: Shanghai Pujiang Talent, Shanghai Science and Technology Commission

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1992.09 - 1996.07 Bachelor's in Biochemistry: East China University of Science and Technology
1999.09 - 2001.12 Master's in Biochemistry and Molecular Biology: Shanghai Institute of Life Sciences, Chinese Academy of Sciences
2002.09 - 2008.05 Ph.D. in Biochemistry and Molecular Biology: Shanghai Institute of Life Sciences, Chinese Academy of Sciences

Work Experience

1996.07 - 1997.06 - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Research Intern
1997.07 - 2000.06 - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Research Assistant
2000.07 - 2000.04 - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Assistant Researcher
2008.05 - 2009.05 - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Associate Researcher
2009.05 - 2013.03 - Yale University School of Medicine - Postdoctoral Fellow
2013.06 - Present - Fudan University, School of Basic Medical Sciences, Department of Biochemistry and Molecular Biology - Researcher

Awards

2014: Shanghai Pujiang Talent, Shanghai Science and Technology Commission

Areas of Focus	Cell Biology: Metabolism and Cell Signal Transduction
Publications	FNDC5/irisin facilitates muscle−adipose−bone connectivity through ubiquitination- dependent activation of runt-related transcriptional factors RUNX1/2, He, X.Y., Hua, Y., Li, Q., Zhu, W., Pan, Y., Yang, Y.L., Li, X.Y., Wu, M.X., Wang, J.Y., Gan, X.Q., 2022 Oligomerization of Frizzled and low-density lipoprotein receptor-related protein 5/6 initiates intracellular signaling for the canonical WNT/β-catenin pathway, Hua, Y., Yang, Y.L., Li, Q., He, X.Y., Zhu, W., Wang, J.Y., Gan. X.Q., 2018 T Cell Factor 7 (TCF7)/TCF1 feedback controls osteocalcin signaling in brown adipocytes independent of Wnt/b-catenin pathway, Li, Q., Hua, Y., Yang, Y.L., He, X.Y., Zhu, W., Wang, J.Y., Gan. X.Q., 2018 The E3 ubiquitin ligase WWP2 facilitates RUNX2 protein transactivation in a mono-ubiquitination manner during osteogenic differentiation, Zhu, W., He, X.Y., Hua, Y., Li, Q., Wang, J.Y., Gan. X.Q., 2017 PRR5L degradation promotes mTORC2-mediated PKC- phosphorylation and cell migration downstream of G12, Gan. X.Q., Wang, J.Y., Wang, C., Sommer, E., Kozasa, T., Srinivasula, S., Alessi, D., Offermanns, S., Simon, M.I., Wu, D.Q., 2012 Evidence for direct activation of mTORC2 kinase activity by phosphatidylinositol 3, 4, 5-trisphophate, Gan. X.Q., Wang, J.Y., Su, B., Wu, D.Q., 2011 Nuclear Dishevelled, c-Jun, -Catenin and TCF form a complex leading to stabilization of -catenin/TCF interaction, Gan. X.Q., Wang, J.Y., Xi, Y., Wu, Z.L., Li, Y.P., Li, L., 2008

Areas of Focus

Cell Biology: Metabolism and Cell Signal Transduction

Publications

FNDC5/irisin facilitates muscle−adipose−bone connectivity through ubiquitination- dependent activation of runt-related transcriptional factors RUNX1/2, He, X.Y., Hua, Y., Li, Q., Zhu, W., Pan, Y., Yang, Y.L., Li, X.Y., Wu, M.X., Wang, J.Y., Gan, X.Q., 2022
Oligomerization of Frizzled and low-density lipoprotein receptor-related protein 5/6 initiates intracellular signaling for the canonical WNT/β-catenin pathway, Hua, Y., Yang, Y.L., Li, Q., He, X.Y., Zhu, W., Wang, J.Y., Gan. X.Q., 2018
T Cell Factor 7 (TCF7)/TCF1 feedback controls osteocalcin signaling in brown adipocytes independent of Wnt/b-catenin pathway, Li, Q., Hua, Y., Yang, Y.L., He, X.Y., Zhu, W., Wang, J.Y., Gan. X.Q., 2018
The E3 ubiquitin ligase WWP2 facilitates RUNX2 protein transactivation in a mono-ubiquitination manner during osteogenic differentiation, Zhu, W., He, X.Y., Hua, Y., Li, Q., Wang, J.Y., Gan. X.Q., 2017
PRR5L degradation promotes mTORC2-mediated PKC- phosphorylation and cell migration downstream of G12, Gan. X.Q., Wang, J.Y., Wang, C., Sommer, E., Kozasa, T., Srinivasula, S., Alessi, D., Offermanns, S., Simon, M.I., Wu, D.Q., 2012
Evidence for direct activation of mTORC2 kinase activity by phosphatidylinositol 3, 4, 5-trisphophate, Gan. X.Q., Wang, J.Y., Su, B., Wu, D.Q., 2011
Nuclear Dishevelled, c-Jun, -Catenin and TCF form a complex leading to stabilization of -catenin/TCF interaction, Gan. X.Q., Wang, J.Y., Xi, Y., Wu, Z.L., Li, Y.P., Li, L., 2008

Metabolism Cell Signaling Biochemistry Molecular Biology Cell Biology Signal Transduction Wnt Pathway Runx2 Osteogenesis Adipogenesis

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