Professor | Xiaowu Hong | Asia Growth Partners

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Name	Xiaowu Hong
Contact Information	nxiaowuhong@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Xiaowu Hong

Contact Information

nxiaowuhong@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1995.09—2000.07 Bachelor's Degree: Wannan Medical College 2000.09—2003.07 Master's Degree: Southeast University 2003.09—2006.07 Doctoral Degree: Fudan University
Work Experience	2010.08—2012.03 - University of Louisville Brown Cancer Center, Department of Microbiology and Immunology - Postdoctoral Researcher 2006.09—Present - Fudan University, School of Basic Medical Sciences, Department of Immunology - Assistant, Lecturer, Master's Supervisor
Awards	Fudan University Huazang Award Fudan University Excellent Tutor Award

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1995.09—2000.07 Bachelor's Degree: Wannan Medical College
2000.09—2003.07 Master's Degree: Southeast University
2003.09—2006.07 Doctoral Degree: Fudan University

Work Experience

2010.08—2012.03 - University of Louisville Brown Cancer Center, Department of Microbiology and Immunology - Postdoctoral Researcher
2006.09—Present - Fudan University, School of Basic Medical Sciences, Department of Immunology - Assistant, Lecturer, Master's Supervisor

Awards

Fudan University Huazang Award
Fudan University Excellent Tutor Award

Areas of Focus	Research on anti-infection immunity and its molecular mechanisms Study on the impact of intestinal epithelial cell exosomes on the stability of sIgA in the intestinal mucosal system and immune barrier How the signaling pathways mediated by intestinal epithelial cell exosomes cross-talk with the LPS/TLR4/NF-kB signaling pathway to inhibit LPS-induced inflammatory response
Publications	Helicobacter Pylori CagA interacts with SHP-1 to suppress the immune response by targeting TRAF6 for K63-linked ubiquitination, He H, Liu J, Li L, Qian G, Hao D, Li M, Zhang Y, Hong X, Xu J, Yan D, 2021 MicroRNA30a controls the instability of inducible CD4+ Tregs through SOCS1, Zhou Y, Li YJ, Li, Lu J, Hong XW, Xu L, 2019 Comprehensive RNA-Seq Data Analysis Identifies Key mRNAs and lncRNAs in Atrial fibrillation, Wu DM, Zhou ZK, Fan SH, Zheng ZH, Wen X, Han XR, Wang S, Wang YJ, Zhang ZF, Shan Q, Li MQ, Hu B, Lu J, Chen GQ, Hong XW, Zheng YL, 2019 MicroRNA-17 inhibition overcomes chemoresistance and suppresses epithelial-mesenchymal transition through a DEDD-dependent mechanism in gastric cancer, Wu DM, Hong XW, Wang LL, Cui XF, Lu J, Chen GQ, Zheng YL, 2018 Lipoprotein (a) as a Predictor of Early Stroke Recurrence in Acute Ischemic Stroke, Hong XW, Wu DM, Lu J, Zheng YL, Tu WJ, Yan J, 2018 Effects of exosome on the activation of CD4+T cells in rhesus macaques: a potential application for HIV latency reactivation, Hong X, Schouest B, Xu H, 2017

Areas of Focus

Research on anti-infection immunity and its molecular mechanisms
Study on the impact of intestinal epithelial cell exosomes on the stability of sIgA in the intestinal mucosal system and immune barrier
How the signaling pathways mediated by intestinal epithelial cell exosomes cross-talk with the LPS/TLR4/NF-kB signaling pathway to inhibit LPS-induced inflammatory response

Publications

Helicobacter Pylori CagA interacts with SHP-1 to suppress the immune response by targeting TRAF6 for K63-linked ubiquitination, He H, Liu J, Li L, Qian G, Hao D, Li M, Zhang Y, Hong X, Xu J, Yan D, 2021
MicroRNA30a controls the instability of inducible CD4+ Tregs through SOCS1, Zhou Y, Li YJ, Li, Lu J, Hong XW, Xu L, 2019
Comprehensive RNA-Seq Data Analysis Identifies Key mRNAs and lncRNAs in Atrial fibrillation, Wu DM, Zhou ZK, Fan SH, Zheng ZH, Wen X, Han XR, Wang S, Wang YJ, Zhang ZF, Shan Q, Li MQ, Hu B, Lu J, Chen GQ, Hong XW, Zheng YL, 2019
MicroRNA-17 inhibition overcomes chemoresistance and suppresses epithelial-mesenchymal transition through a DEDD-dependent mechanism in gastric cancer, Wu DM, Hong XW, Wang LL, Cui XF, Lu J, Chen GQ, Zheng YL, 2018
Lipoprotein (a) as a Predictor of Early Stroke Recurrence in Acute Ischemic Stroke, Hong XW, Wu DM, Lu J, Zheng YL, Tu WJ, Yan J, 2018
Effects of exosome on the activation of CD4+T cells in rhesus macaques: a potential application for HIV latency reactivation, Hong X, Schouest B, Xu H, 2017

Anti-Infection Immunity Molecular Mechanisms Intestinal Epithelial Cells Exosomes Siga Immune Barrier Lps Tlr4 Nf-Kb

Pang Wei - China Medical University

Dapeng Yan - Fudan University

Huabing Li - Chongqing Medical University

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