Professor | Dapeng Yan | Asia Growth Partners

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Name	Dapeng Yan
Contact Information	dapengyan@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Dapeng Yan

Contact Information

dapengyan@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2003.09—2007.09 Bachelor's Degree: Tongji University, School of Life Sciences and Technology 2007.09—2013.07 Doctoral Degree: Shanghai Institute of Health Sciences, Chinese Academy of Sciences
Work Experience	2013.07—2015.08 - Harvard Medical School, Department of Microbiology and Immunology - Postdoctoral Fellow 2015.09—2020.11 - Fudan University, School of Basic Medical Sciences, Department of Immunology - Researcher (Youth), Doctoral Supervisor 2020.12—Present - Fudan University, School of Basic Medical Sciences, Department of Immunology - Professor, Doctoral Supervisor
Awards	2021: Fudan University Shanghai Medical College Excellent Teacher Award 2021: School of Basic Medical Sciences Excellent Party Worker 2020: China Health and Health Ideological and Political Work Promotion Association 'Excellent Ideological and Political Worker' 2019: Third Prize in Fudan University Young Teacher Teaching Competition 2019: First Prize in School of Basic Medical Sciences Young Teacher Teaching Competition 2018: First Prize in Natural Science by Ministry of Education 2017: School of Basic Medical Sciences 'Shangyi' Talent 2016: Chinese Society of Immunology Young Scholar Award 2014: Chinese Academy of Sciences Excellent Doctoral Dissertation 2013: Chinese Academy of Sciences President's Special Award 2012: Meiji Dairy Life Science Award

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2003.09—2007.09 Bachelor's Degree: Tongji University, School of Life Sciences and Technology
2007.09—2013.07 Doctoral Degree: Shanghai Institute of Health Sciences, Chinese Academy of Sciences

Work Experience

2013.07—2015.08 - Harvard Medical School, Department of Microbiology and Immunology - Postdoctoral Fellow
2015.09—2020.11 - Fudan University, School of Basic Medical Sciences, Department of Immunology - Researcher (Youth), Doctoral Supervisor
2020.12—Present - Fudan University, School of Basic Medical Sciences, Department of Immunology - Professor, Doctoral Supervisor

Awards

2021: Fudan University Shanghai Medical College Excellent Teacher Award
2021: School of Basic Medical Sciences Excellent Party Worker
2020: China Health and Health Ideological and Political Work Promotion Association 'Excellent Ideological and Political Worker'
2019: Third Prize in Fudan University Young Teacher Teaching Competition
2019: First Prize in School of Basic Medical Sciences Young Teacher Teaching Competition
2018: First Prize in Natural Science by Ministry of Education
2017: School of Basic Medical Sciences 'Shangyi' Talent
2016: Chinese Society of Immunology Young Scholar Award
2014: Chinese Academy of Sciences Excellent Doctoral Dissertation
2013: Chinese Academy of Sciences President's Special Award
2012: Meiji Dairy Life Science Award

Areas of Focus	Research on infection immunity and its molecular mechanisms Molecular mechanisms of pathogen immune evasion
Publications	HIV-1 Vif suppresses antiviral immunity by targeting STING, Wang Y#, Qian G#, Zhu L#, Zhao Z#, Liu Y, Han W, Zhang X, Zhang Y, Xiong T, Zeng H, Yu X, Yu X, Zhang X, Xu J, Zou Q, Yan D, 2022 Helicobacter Pylori CagA interacts with SHP-1 to suppress the immune response by targeting TRAF6 for K63-linked ubiquitination, He H#, Liu J#, Li L, Qian G, Hao D, Li M, Zhang Y, Hong X, Xu J, Yan D, 2021 β-arrestin 2 as an activator of cGAS-STING signaling and target of viral immune evasion, Zhang Y#, Li M#, Li L, Qian G, Wang Y, Chen Z, Liu J, Fang C, Huang F, Guo D, Chu Y, Yan D, 2020 SHP-1 suppresses the antiviral innate immune response by targeting TRAF3, Hao D#, Wang Y#, Li L, Qian G, Liu J, Li M, Zhang Y, Zhou R, Yan D, 2020 β-Arrestin 2 quenches TLR signaling to facilitate the immune evasion of EPEC, Chen Z#, Zhou R#, Zhang Y#, Hao D, Wang Y, Huang S, Liu N, Xia C, Yissachar N, Chu Y, Yan D, 2020 Enterohemorrhagic Escherichia coli Tir inhibits TAK1 activation and mediates immune evasion, Zhou R#, Chen Z#, Hao D, Wang Y, Zhang Y, Yi X, Lyu LD, Liu H, Zou Q, Chu Y, Ge B, Yan D, 2019 PLCβ2 Negatively Regulates the Inflammatory Response to Virus Infection by Inhibiting Phosphoinositide-mediated Activation of TAK1, Wang L#, Zhou Y#, Chen Z#, Sun L, Wu J, Li H, Liu F, Wang F, Yang C, Yang J, Leng Q, Zhang Q, Xu A, Shen L, Sun J, Wu D, Fang C, Lu H, Yan D, Ge B, 2019 Modulation of host signaling in inflammatory response by enteropathogenic Escherichia coli virulence proteins, Zhuang X#, Chen Z#, He C, Wang L, Zhou R, Yan D, Ge B, 2017 Imbalanced signal transduction in regulatory T cells expressing the transcription factor FoxP3, Yan D, Farache J, Mingueneau M, Mathis D, Benoist C, 2015 Inhibition of TLR signaling by a bacterial protein containing immunoreceptor tyrosine-based inhibitory motifs, Yan D, Wang X, Luo L, Cao X, Ge B, 2012

Areas of Focus

Research on infection immunity and its molecular mechanisms
Molecular mechanisms of pathogen immune evasion

Publications

HIV-1 Vif suppresses antiviral immunity by targeting STING, Wang Y#, Qian G#, Zhu L#, Zhao Z#, Liu Y, Han W, Zhang X, Zhang Y, Xiong T, Zeng H, Yu X, Yu X, Zhang X, Xu J*, Zou Q*, Yan D*, 2022
Helicobacter Pylori CagA interacts with SHP-1 to suppress the immune response by targeting TRAF6 for K63-linked ubiquitination, He H#, Liu J#, Li L, Qian G, Hao D, Li M, Zhang Y, Hong X, Xu J, Yan D*, 2021
β-arrestin 2 as an activator of cGAS-STING signaling and target of viral immune evasion, Zhang Y#, Li M#, Li L, Qian G, Wang Y, Chen Z, Liu J, Fang C, Huang F, Guo D, Chu Y, Yan D*, 2020
SHP-1 suppresses the antiviral innate immune response by targeting TRAF3, Hao D#, Wang Y#, Li L, Qian G, Liu J, Li M, Zhang Y, Zhou R, Yan D*, 2020
β-Arrestin 2 quenches TLR signaling to facilitate the immune evasion of EPEC, Chen Z#, Zhou R#, Zhang Y#, Hao D, Wang Y, Huang S, Liu N, Xia C, Yissachar N, Chu Y, Yan D*, 2020
Enterohemorrhagic Escherichia coli Tir inhibits TAK1 activation and mediates immune evasion, Zhou R#, Chen Z#, Hao D, Wang Y, Zhang Y, Yi X, Lyu LD, Liu H, Zou Q, Chu Y, Ge B, Yan D*, 2019
PLCβ2 Negatively Regulates the Inflammatory Response to Virus Infection by Inhibiting Phosphoinositide-mediated Activation of TAK1, Wang L#, Zhou Y#, Chen Z#, Sun L, Wu J, Li H, Liu F, Wang F, Yang C, Yang J, Leng Q, Zhang Q, Xu A, Shen L, Sun J, Wu D, Fang C, Lu H*, Yan D*, Ge B*, 2019
Modulation of host signaling in inflammatory response by enteropathogenic Escherichia coli virulence proteins, Zhuang X#, Chen Z#, He C, Wang L, Zhou R, Yan D*, Ge B*, 2017
Imbalanced signal transduction in regulatory T cells expressing the transcription factor FoxP3, Yan D, Farache J, Mingueneau M, Mathis D*, Benoist C*, 2015
Inhibition of TLR signaling by a bacterial protein containing immunoreceptor tyrosine-based inhibitory motifs, Yan D, Wang X, Luo L, Cao X, Ge B*, 2012

Infection Immunity Molecular Mechanisms Pathogen Immune Evasion Research Immunology Microbiology Health Sciences Biology

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