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Dapeng Yan
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, English
Infection
Immunity
Molecular Mechanisms
Pathogen
Immune Evasion
Research
Immunology
Microbiology
Health Sciences
Biology
Areas of Focus
- Research on infection immunity and its molecular mechanisms
- Molecular mechanisms of pathogen immune evasion
Work Experience
- 2013.07—2015.08 - Harvard Medical School, Department of Microbiology and Immunology - Postdoctoral Fellow
- 2015.09—2020.11 - Fudan University, School of Basic Medical Sciences, Department of Immunology - Researcher (Youth), Doctoral Supervisor
- 2020.12—Present - Fudan University, School of Basic Medical Sciences, Department of Immunology - Professor, Doctoral Supervisor
Academic Background & Achievements
- 2003.09—2007.09 Bachelor's Degree: Tongji University, School of Life Sciences and Technology
- 2007.09—2013.07 Doctoral Degree: Shanghai Institute of Health Sciences, Chinese Academy of Sciences
Publications
- HIV-1 Vif suppresses antiviral immunity by targeting STING, Wang Y#, Qian G#, Zhu L#, Zhao Z#, Liu Y, Han W, Zhang X, Zhang Y, Xiong T, Zeng H, Yu X, Yu X, Zhang X, Xu J*, Zou Q*, Yan D*, 2022
- Helicobacter Pylori CagA interacts with SHP-1 to suppress the immune response by targeting TRAF6 for K63-linked ubiquitination, He H#, Liu J#, Li L, Qian G, Hao D, Li M, Zhang Y, Hong X, Xu J, Yan D*, 2021
- β-arrestin 2 as an activator of cGAS-STING signaling and target of viral immune evasion, Zhang Y#, Li M#, Li L, Qian G, Wang Y, Chen Z, Liu J, Fang C, Huang F, Guo D, Chu Y, Yan D*, 2020
- SHP-1 suppresses the antiviral innate immune response by targeting TRAF3, Hao D#, Wang Y#, Li L, Qian G, Liu J, Li M, Zhang Y, Zhou R, Yan D*, 2020
- β-Arrestin 2 quenches TLR signaling to facilitate the immune evasion of EPEC, Chen Z#, Zhou R#, Zhang Y#, Hao D, Wang Y, Huang S, Liu N, Xia C, Yissachar N, Chu Y, Yan D*, 2020
- Enterohemorrhagic Escherichia coli Tir inhibits TAK1 activation and mediates immune evasion, Zhou R#, Chen Z#, Hao D, Wang Y, Zhang Y, Yi X, Lyu LD, Liu H, Zou Q, Chu Y, Ge B, Yan D*, 2019
- PLCβ2 Negatively Regulates the Inflammatory Response to Virus Infection by Inhibiting Phosphoinositide-mediated Activation of TAK1, Wang L#, Zhou Y#, Chen Z#, Sun L, Wu J, Li H, Liu F, Wang F, Yang C, Yang J, Leng Q, Zhang Q, Xu A, Shen L, Sun J, Wu D, Fang C, Lu H*, Yan D*, Ge B*, 2019
- Modulation of host signaling in inflammatory response by enteropathogenic Escherichia coli virulence proteins, Zhuang X#, Chen Z#, He C, Wang L, Zhou R, Yan D*, Ge B*, 2017
- Imbalanced signal transduction in regulatory T cells expressing the transcription factor FoxP3, Yan D, Farache J, Mingueneau M, Mathis D*, Benoist C*, 2015
- Inhibition of TLR signaling by a bacterial protein containing immunoreceptor tyrosine-based inhibitory motifs, Yan D, Wang X, Luo L, Cao X, Ge B*, 2012
Awards
- 2021: Fudan University Shanghai Medical College Excellent Teacher Award
- 2021: School of Basic Medical Sciences Excellent Party Worker
- 2020: China Health and Health Ideological and Political Work Promotion Association 'Excellent Ideological and Political Worker'
- 2019: Third Prize in Fudan University Young Teacher Teaching Competition
- 2019: First Prize in School of Basic Medical Sciences Young Teacher Teaching Competition
- 2018: First Prize in Natural Science by Ministry of Education
- 2017: School of Basic Medical Sciences 'Shangyi' Talent
- 2016: Chinese Society of Immunology Young Scholar Award
- 2014: Chinese Academy of Sciences Excellent Doctoral Dissertation
- 2013: Chinese Academy of Sciences President's Special Award
- 2012: Meiji Dairy Life Science Award
