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Xiaowei Zhang
Basic Medical Sciences
Peking University
Beijing
Language: Chinese, English
Cellular Aging
Cancer
Molecular Mechanisms
Research
Cell Senescence
Tumor Genesis
Molecular Biology
Biochemistry
Cell Biology
Oncology
Areas of Focus
- Cellular aging
- Cancer development
Work Experience
- 1999-2003 - Peking University, Department of Biochemistry and Molecular Biology - Professor
- 2003-2006 - Tufts University, USA - Postdoctoral Research
- 2001-2013 - Peking University, Department of Biochemistry and Molecular Biology - Associate Professor
- 2013-Present - Peking University, Department of Biochemistry and Molecular Biology - Professor
Academic Background & Achievements
- 1994-1999 PhD: Peking University, Department of Biochemistry and Molecular Biology
Publications
- PIASxα enhances SUMO1 modification of PTEN as a SUMO E3 ligase, Zhang X*, 2014
- HBP1-mediated transcriptional regulation of DNA methyltransferase 1 and its impact on cell senescence, Zhang X*, 2013
- The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression, Zhang X*, 2012
- Transcriptional factor HBP1 targets P16INK4A, upregulating its expression and consequently is involved in Ras-induced premature senescence, Zhang X*, 2010
- The HBP1 transcriptional repressor participates in Ras-induced premature senescence, Zhang X, 2006
- Delivering antisense telomerase RNA by a hybrid adenovirus/adeno-associated virus significantly suppresses the malignant phenotype and enhances cell apoptosis of human breast cancer cells, Zhang X, 2003
