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Guo-Gang Xing
Basic Medical Sciences
Peking University
Beijing
Language: English, Chinese
Pain
Memory
Cognition
Emotion
Molecular Biology
Cell Biology
Genomics
Metabolomics
Single-Cell Sequencing
Neurobiology
Stem Cells
Neurodevelopmental Disorders
Cell Reprogramming
Organoids
Disease Mechanisms
Gene Editing
Male Infertility
Reproductive Disorders
Electrophysics
Epigenetics
Areas of Focus
- Pain and memory, cognitive and emotional mechanisms
- Stem cells and neurodevelopmental disorders
- Male reproductive cell development disorders and infertility mechanisms
Work Experience
- 2003 - Present: Various positions at Peking University Institute of Neuroscience, including Lecturer, Associate Professor, and Professor
- 2004 - 2006: Advanced visiting scholar at Sanford Burnham Prebys Medical Discovery Institute and University of Wisconsin Department of Neuroscience
Academic Background & Achievements
- 2001 - PhD from Xi'an Jiaotong University
- Published over 100 research papers
- Co-authored 8 textbooks and monographs
Publications
- Discovery of small-molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and their preclinical neuroprotective activity, Hong Yao, Minghui Liu, Leibo Wang, Yumeng Zu, Chou Wu, Chenyu Li, Ruoxi Zhang, Haigen Lu, Feifei Li, Shuang Xi, Shuangquan Chen, Xuanyu Gu, Tianya Liu, Jie Cai, Shirong Wang, Maojun Yang, Guo-Gang Xing, Wei Xiong, Lan Hua, Yefeng Tang and Gelin Wang, 2022
- Effect of moxa smoke on sperm parameters and oxidative stress in rats with asthenozoospermia, Yajie Liu, YuAn, Guo-Gang Xing, Zirun Jin, KeXi, Yongwei Huo, Rui He, Hao Wang, Xiali Ouyang, Yueping Huang, Chang Huang, Li Han, Baixiao Zhao, 2022
- Spinal microglial activation promotes perioperative social defeat stress-induced prolonged postoperative pain in a sex-dependent manner, Wang Wang, Wei-Zhen Liu, Zi-Liang Wang, Dong-Xiao Duan, Xue-Yun Wang, Shi-Jin Liu, Zhi-Ju Wang, Guo-Gang Xing, Ying Xing, 2022
- Hydroxyapatite Nanorods Function as Safe and Effective Growth Factors Regulating Neural Differentiation and Neuron Development, Min Hao, Zixian Zhang, Chao Liu, Yue Tian, Jiazhi Duan, Jianlong He, Zhaoyang Sun, He Xia, Shan Zhang, Shuhua Wang, Yuanhua Sang, Guo-Gang Xing, Hong Liu, 2021
- Contribution of AMPA receptor-mediated LTD in LA/BLA-CeA pathway to comorbid aversive and depressive symptoms in neuropathic pain, Hong Jiang, Jiang-Ping Liu, Ke Xi, Ling-Yu Liu, Ling-Yu Kong, Jie Cai, Si-Qing Cai, Xi-Yuan Han, Jing-Gui Song, Xiao-Mei Yang, You Wan, Guo-Gang Xing, 2021
- Contribution of TRESK two-pore domain potassium channel to bone cancer-induced spontaneous pain and evoked cutaneous pain in rats, Jiang-Ping Liu, Hong-Bo Jing, Ke Xi, Zi-Xian Zhang, Zi-Run Jin, Si-Qing Cai, Yue Tian, Jie Cai, Guo-Gang Xing, 2021
- Roles of CatSper channels in the pathogenesis of asthenozoospermia and the therapeutic effects of acupuncture-like treatment on asthenozoospermia, Zi-Run Jin, Dong Fang, Bo-Heng Liu, Jie Cai, Wen-Hao Tang, Hui Jiang, Guo-Gang Xing, 2021
- Phenotype and genotype study of chinese POMT2-related a-dystroglycanopathy, Xiao-Yu Chen, Dan-Yu Song, Li Jiang, Dan-Dan Tan, Yi-Dan Liu, Jie-Yu Liu, Xing-Zhi Chang, Guo-Gang Xing, Tatsushi Toda, Hui Xiong, 2021
- FAM19A5/TAFA5, a novel neurokine, plays a crucial role in depressive-like and spatial memory-related behaviors in mice, Shiyang Huang, Can Zheng, Guoguang Xie, Zhanming Song, Pingzhang Wang, Yun Bai, Dixin Chen, Yan Zhang, Ping Lv, Weiwei Liang, Shaoping She, Qingqing Li, Zhongtian Liu, Yun Wang, Guo-Gang Xing, Ying Wang, 2021
- Responses of Primary Afferent Fibers to Acupuncture-Like Peripheral Stimulation at Different Frequencies: Characterization by Single-Unit Recording in Rats, Ran Huo, Song-Ping Han, Feng-Yu Liu, Xiao-Jing Shou, Ling-Yu Liu, Tian-Jia Song, Fu-Jun Zhai, Rong Zhang, Guo-Gang Xing, Ji-Sheng Han, 2020
- Electroacupuncture modulates spinal BDNF/TrkB signaling pathway and ameliorates the sensitization of dorsal horn WDR neurons in spared nerve injury rats, Meng Xue, Ya-Lan Sun, Yang-Yang Xia, Zhi-Hua Huang, Cheng Huang, Guo-Gang Xing, 2020
- Contribution of microglial reaction to increased nociceptive responses in high-fat-diet (HFD)-induced obesity in male mice, Ya-Jing Liang, Shi-Yang Feng, Ya-Ping Qi, Kai Li, Zi-Run Jin, Hong-Bo Jing, Ling-Yu Liu, Jie Cai, Guo-Gang Xing, Kai-Yuan Fu, 2019
- High frequency stimulation of subthalamic nucleus synchronously modulates primary motor cortex and caudate putamen based on dopamine concentration and electrophysiology activities using microelectrode arrays in Parkinson's disease rats, Yu Zhang, Shengwei Xu, Guihua Xiao, Yilin Song, Fei Gao, Mixia Wang, Hongyan Zhao, Guogang Xing, Xinxia Cai, 2019
- Microelectrode Arrays Modified with Nanocomposites for Monitoring Dopamine and Spike Firings under Deep Brain Stimulation in Rat Models of Parkinson's Disease, Guihua Xiao, Yilin Song, Yu Zhang, Yu Xing, Hongyan Zhao, Jingyu Xie, Shengwei Xu, Fei Gao, Mixia Wang, Guogang Xing, Xinxia Cai, 2019
- Chronic stress increases pain sensitivity via activation of the rACC–BLA pathway in rats, Ling-Yu Liu, Rui-Ling Zhang, Lin Chen, Hong-Yan Zhao, Jie Cai, Jia-Kang Wang, Da-Qing Guo, Yan-Jun Cui, Guo-Gang Xing, 2019
- Decreased abundance of TRESK two-pore domain potassium channels in sensory neurons underlies the pain associated with bone metastasis, Yue Yang, Song Li, Zi-Run Jin, Hong-Bo Jing, Hong-Yan Zhao, Bo-Heng Liu, Ya-Jing Liang, Ling-Yu Liu, Jie Cai, You Wan, Guo-Gang Xing, 2018
- Electroacupuncture Treatment Alleviates the Remifentanil-induced Hyperalgesia by Regulating the Activities of Ventral Posterior Lateral Nucleus of the Thalamus Neurons in Rats, Hong-Yan Zhao, Ling-Yu Liu, Jie Cai, Yan-Jun Cui, Guo-Gang Xing, 2018
- Activation of CRF/CRFR1 signaling in the basolateral nucleus of the amygdala contributes to chronic forced swim-induced depressive-like behaviors in rats, Lin Chen, Song Li, Jie Cai, Tian-Jiao Wei, Ling-Yu Liu, Hong-Yan Zhao, Bo-Heng Liu, Hong-Bo Jing, Zi-Run Jin, Min Liu, You Wan, Guo-Gang Xing, 2018
- BDNF contributes to the neonatal incision-induced facilitation of spinal long-term potentiation and the exacerbation of incisional pain in adult rats, Xu Ding, Ya-Jing Liang, Li Su, Fei-Fei Liao, Dong Fang, Jun Tai, Guo-Gang Xing, 2018
- Chronic stress exacerbates neuropathic pain via the integration of stress-affect related information and nociceptive information in the central nucleus of the amygdala, Ming-Jia Li, Ling-Yu Liu, Lin Chen, Jie Cai, You Wan, Guo-Gang Xing, 2017
- BDNF contributes to spinal long-term potentiation and mechanical hypersensitivity via Fyn-mediated phosphorylation of NMDA receptor GluN2B subunit at tyrosine 1472 in rats following spinal nerve ligation, Song Li, Jie Cai, Zhi-Bo Feng, Zi-Run Jin, Bo-Heng Liu, Hong-Yan Zhao, Hong-Bo Jing, Tian-Jiao Wei, Guan-Nan Yang, Ling-Yu Liu, Yan-Jun Cui, Guo-Gang Xing, 2017
- Protective effects of oxymatrine against arsenic trioxide-induced liver injury, Li Li, Qinghai Liu, Long Fan, Wei Xiao, Lei Zhao, Yu Wang, Weiguang Ye, Fei Lan, Bin Jia, Hua Feng, Changman Zhou, Xiuqin Yue, Guo-Gang Xing, Tianlong Wang, 2017
- Re-exposure to morphine-associated context facilitated long-term potentiation in the vSUB-NAc glutamatergic pathway via GluN2B-containing receptor activation, Yi-Jing Li, Xing-Jie Ping, Chong Qi, Fang Shen, Lin-Lin Sun, Xiao-Wei Sun, Fei-Fei Ge, Guo-Gang Xing, Cai-Lian Cui, 2017
- Enhanced Gamma Oscillatory Activity in Rats with Chronic Inflammatory Pain, Jing Wang, Jing Wang, Guo-Gang Xing,
Awards
- 2019 Beijing Natural Science Award, Second Prize
- 2012 Beijing Science and Technology Award, Second Prize
- 2010 China Acupuncture Society Science and Technology Award, Second Prize
