Professor | Limin Lu | Asia Growth Partners

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Name	Limin Lu
Contact Information	nlulimin@shmu.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Limin Lu

Contact Information

nlulimin@shmu.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1993.09—1996.07 PhD in Physiology: Shanghai Medical University 1990.09—1993.07 Master's in Physiology: Shanghai Medical University 1983.09—1988.07 Bachelor's: Shanghai Medical University
Work Experience	2009-present - Fudan University - Professor 1997-2009 - Fudan University - Associate Professor 1994-1997 - Shanghai Medical University - Lecturer 2006-2008 - University of Wisconsin - Visiting Scholar
Awards	Shanghai Science and Technology Award Second Prize (2020): Shanghai Municipal Government Fudan University Shanghai Medical College Excellent Teacher Award (2017): Fudan University Ministry of Education Science and Technology Progress Award Second Prize (2004): Ministry of Education Fudan University Shanghai Bank Basic Medical Education Young and Middle-aged Award First Prize (2002): Fudan University Shanghai Science and Technology Progress Second Prize (2001): Shanghai Municipal Government China University Science and Technology Progress Second Prize (2000): Ministry of Education Ministry of Education Huo Yingdong Foundation National Excellent Young Teacher Third Prize (1997): Ministry of Education

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1993.09—1996.07 PhD in Physiology: Shanghai Medical University
1990.09—1993.07 Master's in Physiology: Shanghai Medical University
1983.09—1988.07 Bachelor's: Shanghai Medical University

Work Experience

2009-present - Fudan University - Professor
1997-2009 - Fudan University - Associate Professor
1994-1997 - Shanghai Medical University - Lecturer
2006-2008 - University of Wisconsin - Visiting Scholar

Awards

Shanghai Science and Technology Award Second Prize (2020): Shanghai Municipal Government
Fudan University Shanghai Medical College Excellent Teacher Award (2017): Fudan University
Ministry of Education Science and Technology Progress Award Second Prize (2004): Ministry of Education
Fudan University Shanghai Bank Basic Medical Education Young and Middle-aged Award First Prize (2002): Fudan University
Shanghai Science and Technology Progress Second Prize (2001): Shanghai Municipal Government
China University Science and Technology Progress Second Prize (2000): Ministry of Education
Ministry of Education Huo Yingdong Foundation National Excellent Young Teacher Third Prize (1997): Ministry of Education

Areas of Focus	Mechanisms of acute and chronic kidney injury Mechanisms of diabetes-induced kidney and cardiovascular damage
Publications	Caspase-11 promotes NLRP3 inflammasome activation via the cleavage of pannexin 1 in acute kidney disease, Yin F, Zhen PQ, Zhao LQ, Wang YZ, Miao NJ, Zhou ZL, Cheng Q, Chen PP, Xie HY, Li JY, Ni JY, Zhou L, Zhang W, Wang XX, Liu J, Lu LM, 2022 FoxM1 promotes Wnt/β-catenin pathway activation and renal fibrosis via transcriptionally regulating multi-Wnts expressions, Xie H, Miao N, Xu D, Zhou Z, Ni J, Yin F, Wang Y, Cheng Q, Chen P, Li J, Zheng P, Zhou L, Liu J, Zhang W, Wang X, Lu L, 2021 Caspase-11/4 and gasdermin D-mediated pyroptosis contributes to podocyte injury in mouse diabetic nephropathy, Cheng Q, Pan J, Zhou ZL, Yin F, Xie HY, Chen PP, Li JY, Zheng PQ, Zhou L, Zhang W, Liu J, Lu LM, 2021 KLF4 initiates sustained YAP activation to promote renal fibrosis in mice after ischemia-reperfusion kidney injury, Xu D#, Chen PP#, Zheng PQ, Yin F, Cheng Q, Zhou ZL, Xie HY, Li JY, Ni JY, Wang YZ, Chen SJ, Zhou L, Wang XX, Liu J, Zhang W, Lu LM, 2021 RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice, Zhou Z, Ni J, Li J, Huo C, Miao N, Yin F, Cheng Q, Xu D, Xie H, Chen P, Zheng P, Zhang Y, Zhou L, Zhang W, Yu C, Liu J, Lu L, 2020 The cleavage of gasdermin D by caspase-11 promotes tubular epithelial cell pyroptosis and urinary IL-18 excretion in acute kidney injury, Miao N#, Yin F#, Xie H, Wang Y, Xu Y, Shen Y, Xu D, Yin J, Wang B, Zhou Z, Cheng Q, Chen P, Xue H, Zhou L, Liu J, Wang X, Zhang W, Lu L, 2019 Caspase-11 promotes renal fibrosis by stimulating IL-1β maturation via activating caspase-1, Miao NJ#, Xie HY#, Xu D, Yin JY, Wang YZ, Wang B, Yin F, Zhou ZL, Cheng Q, Chen PP, Zhou L, Xue H, Zhang W, Wang XX, Liu J, Lu LM, 2019 Caspase-11 Promotes Cisplatin-Induced Renal Tubular Apoptosis through a Caspase-3-dependent Pathway, Miao N#, Wang B#, Xu D, Wang Y, Gan X, Zhou L, Xue H, Zhang W, Wang X, Lu L, 2018 c-Myc promotes renal fibrosis by inducing integrin av-mediated transforming growth factor-β signaling, Shen Y, Miao N, Wang B, Xu J, Gan X, Xu D, Zhou L, Xue H, Zhang W, Yang L, Lu L, 2017 Metformin Prevents Renal Fibrosis in Mice with Unilateral Ureteral Obstruction and Inhibits Ang II-Induced ECM Production in Renal Fibroblasts, Shen Y, Miao N, Xu J, Gan X, Xu D, Zhou L, Xue H, Zhang W, Lu L, 2016

Areas of Focus

Mechanisms of acute and chronic kidney injury
Mechanisms of diabetes-induced kidney and cardiovascular damage

Publications

Caspase-11 promotes NLRP3 inflammasome activation via the cleavage of pannexin 1 in acute kidney disease, Yin F, Zhen PQ, Zhao LQ, Wang YZ, Miao NJ, Zhou ZL, Cheng Q, Chen PP, Xie HY, Li JY, Ni JY, Zhou L, Zhang W, Wang XX*, Liu J*, Lu LM*, 2022
FoxM1 promotes Wnt/β-catenin pathway activation and renal fibrosis via transcriptionally regulating multi-Wnts expressions, Xie H, Miao N, Xu D, Zhou Z, Ni J, Yin F, Wang Y, Cheng Q, Chen P, Li J, Zheng P, Zhou L, Liu J, Zhang W*, Wang X*, Lu L*, 2021
Caspase-11/4 and gasdermin D-mediated pyroptosis contributes to podocyte injury in mouse diabetic nephropathy, Cheng Q, Pan J, Zhou ZL, Yin F, Xie HY, Chen PP, Li JY, Zheng PQ, Zhou L, Zhang W, Liu J*, Lu LM*, 2021
KLF4 initiates sustained YAP activation to promote renal fibrosis in mice after ischemia-reperfusion kidney injury, Xu D#, Chen PP#, Zheng PQ, Yin F, Cheng Q, Zhou ZL, Xie HY, Li JY, Ni JY, Wang YZ, Chen SJ, Zhou L, Wang XX, Liu J, Zhang W*, Lu LM*, 2021
RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice, Zhou Z, Ni J, Li J, Huo C, Miao N, Yin F, Cheng Q, Xu D, Xie H, Chen P, Zheng P, Zhang Y, Zhou L, Zhang W, Yu C, Liu J*, Lu L*, 2020
The cleavage of gasdermin D by caspase-11 promotes tubular epithelial cell pyroptosis and urinary IL-18 excretion in acute kidney injury, Miao N#, Yin F#, Xie H, Wang Y, Xu Y, Shen Y, Xu D, Yin J, Wang B, Zhou Z, Cheng Q, Chen P, Xue H, Zhou L, Liu J, Wang X*, Zhang W*, Lu L*, 2019
Caspase-11 promotes renal fibrosis by stimulating IL-1β maturation via activating caspase-1, Miao NJ#, Xie HY#, Xu D, Yin JY, Wang YZ, Wang B, Yin F, Zhou ZL, Cheng Q, Chen PP, Zhou L, Xue H, Zhang W, Wang XX, Liu J*, Lu LM*, 2019
Caspase-11 Promotes Cisplatin-Induced Renal Tubular Apoptosis through a Caspase-3-dependent Pathway, Miao N#, Wang B#, Xu D, Wang Y, Gan X, Zhou L, Xue H, Zhang W, Wang X, Lu L*, 2018
c-Myc promotes renal fibrosis by inducing integrin av-mediated transforming growth factor-β signaling, Shen Y, Miao N, Wang B, Xu J, Gan X, Xu D, Zhou L, Xue H, Zhang W, Yang L, Lu L*, 2017
Metformin Prevents Renal Fibrosis in Mice with Unilateral Ureteral Obstruction and Inhibits Ang II-Induced ECM Production in Renal Fibroblasts, Shen Y, Miao N, Xu J, Gan X, Xu D, Zhou L, Xue H, Zhang W, Lu L*, 2016

Acute Kidney Injury Chronic Kidney Disease Diabetes Kidney Damage Cardiovascular Damage Mechanisms Transcription Factors Wnt/Β-Catenin Hippo Pathway Renal Fibrosis

Wei Zhang - Fudan University

Yan Sun - Chongqing Medical University

Rui Chen - Wuhan University

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