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Liang-Dong Lyu
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, English
Bacterial Drug Tolerance
Resistance Mechanisms
Pathogenic Bacteria
Pathogenesis
Persistent Infection
Microbiology
Antibiotic Resistance
Bacterial Metabolism
Genomic Maintenance
Infectious Diseases
Areas of Focus
- Research on bacterial drug tolerance and resistance mechanisms
- Research on pathogenic bacteria pathogenesis and persistent infection mechanisms
Work Experience
- 2015.9—Present - Fudan University - Associate Professor, Doctoral Supervisor
- 2013.1—2015.1 - Li Ka Shing Institute of Biomedical Sciences, Chinese University of Hong Kong - Postdoctoral Researcher
- 2011.1—2013.1 - Shanghai Institute of Life Sciences, Chinese Academy of Sciences - Postdoctoral Researcher
- 2003.7—2005.7 - Chongqing Yongjian Biotechnology Co., Ltd. - Research Assistant
Academic Background & Achievements
- 2005.09—2011.01 PhD in Microbiology: Fudan University
- 1999.09—2003.07 Bachelor's in Biotechnology: Southwest Agricultural University
Publications
- Oxidation of dCTP contributes to antibiotic lethality in stationary-phase mycobacteria, Fan Xiao-Yong, Tang Bi-Kui, Xu Yuan-Yuan, Han Ang-Xuan, Shi Kun-Xiong, Wu Yong-Kai, Ye Yu, Wei Mei-li, Niu Chen, Wong Ka-Wing, Zhao Guo-Ping, Lyu Liang-Dong, 2018
- Housecleaning of pyrimidine nucleotide pool coordinates metabolic adaptation of nongrowing Mycobacterium tuberculosis, Shi Kun-Xiong, Wu Yong-Kai, Tang Bi-Kui, Zhao Guo-Ping, Lyu Liang-Dong, 2019
- A recently evolved diflavin-containing monomeric nitrate reductase is responsible for highly efficient bacterial nitrate assimilation, Wei Tan, Tian-Hua Liao, Jin Wang, Yu Ye, Yu-Chen Wei, Hao-Kui Zhou, Youli Xiao, Xiao-Yang Zhi, Zhi-Hui Shao, Liang-Dong Lyu, Guo-Ping Zhao, 2020
- Mycobacterial fatty acid catabolism is repressed by FdmR to sustain lipogenesis and virulence, Dong Wenyue, Nie Xiaoqun, Zhu Hong, Liu Qingyun, Shi Kunxiong, You Linlin, Zhang Yu, Fan Hongyan, Yan Bo, Niu Chen, Lyu Liang-Dong, Zhao Guo-Ping, Yang Chen, 2021
- H2O2 Concentration-Dependent Kinetics of Gene Expression: Linking the Intensity of Oxidative Stress and Mycobacterial Physiological Adaptation, Wu Mengying, Shan Wenyan, Zhao Guo-Ping, Lyu Liang-Dong, 2022
Awards
- 2010: Meiji Life Science Award
- 2011: Shanghai Outstanding Graduate
