Professor | Jinghe Huang | Asia Growth Partners

Name	Jinghe Huang
Contact Information	jinghehuang@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

Name

Jinghe Huang

Contact Information

jinghehuang@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1995.09—1999.07 Bachelor's Degree: Jinan University, Department of Biology 1999.09—2002.07 Master's Degree: Jinan University, Department of Biology 2002.09—2007.01 Ph.D.: Tsinghua University, Department of Life Sciences
Work Experience	2007.08—2010.12 - Massachusetts General Hospital, MIT and Harvard University - Joint Research Center 2010.11—2016.12 - National Institutes of Health - Postdoctoral Researcher 2017.01—Present - Fudan University - Researcher 2018.06—Present - Shanghai Public Health Clinical Center - Dual-appointed Researcher
Awards	2021: Second Prize in Natural Science Award for Outstanding Scientific Research in Higher Education Institutions, Ministry of Education 2020: Advanced Individual in Fighting COVID-19, Fudan University 2018: Outstanding Contribution Award, Fudan University Basic Medical College 2015: Annual Outstanding Work Award, National Institutes of Health 2014: Annual Outstanding Work Award, National Institutes of Health

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1995.09—1999.07 Bachelor's Degree: Jinan University, Department of Biology
1999.09—2002.07 Master's Degree: Jinan University, Department of Biology
2002.09—2007.01 Ph.D.: Tsinghua University, Department of Life Sciences

Work Experience

2007.08—2010.12 - Massachusetts General Hospital, MIT and Harvard University - Joint Research Center
2010.11—2016.12 - National Institutes of Health - Postdoctoral Researcher
2017.01—Present - Fudan University - Researcher
2018.06—Present - Shanghai Public Health Clinical Center - Dual-appointed Researcher

Awards

2021: Second Prize in Natural Science Award for Outstanding Scientific Research in Higher Education Institutions, Ministry of Education
2020: Advanced Individual in Fighting COVID-19, Fudan University
2018: Outstanding Contribution Award, Fudan University Basic Medical College
2015: Annual Outstanding Work Award, National Institutes of Health
2014: Annual Outstanding Work Award, National Institutes of Health

Areas of Focus	Development and neutralization mechanism of broad-spectrum antiviral neutralizing antibody drugs Biotherapeutic applications of broad-spectrum antiviral neutralizing antibodies Research on prevention and control strategies for emerging infectious diseases
Publications	Novel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and sarbecoviruses, Yingdan Wang, Meiqin Liu, Yaping Shen, Yunping Ma, Xiang Li, Yuanyuan Zhang, Xing-Lou Yang, Mei Liu, Jun Chen, Renhong Yan, Die Luan, Yanqun Wang, Ying Chen, Qimin Wang, Haofeng Lin, Yaning Li, Kaiyue Wu, Tongyu Zhu, Jincun Zhao, Hongzhou Lu, Yumei Wen, Shibo Jiang, Fan Wu, Qiang Zhou, Zheng-Li Shi, Jinghe Huang, 2022 Resistance of SARS-CoV-2 Omicron Variant to Convalescent and CoronaVac Vaccine Plasma, Yingdan Wang, Yunping Ma, Yan Xu, Jiangyan Liu, Xiang Li, Yuyuan Chen, Yan Chen, Jun Xie, Lianbo Xiao, Zheng Xiang, Fan Wu, Jinghe Huang, 2022 Tetrameric NA of Influenza A virus is required to induce protective antibody responses in mice, Xiren Deng, Qimin Wang, Mei Liu, Qinwen Zheng, Fan Wu, Jinghe Huang, 2021 Evaluating the Association of Clinical Characteristics With Neutralizing Antibody Levels in Patients Who Have Recovered From Mild COVID-19 in Shanghai, China, Fan Wu, Mei Liu, Aojie Wang, Lu Lu, Qimin Wang, Chenjian Gu, Jun Chen, Yang Wu, Shuai Xia, Yun Ling, Yuling, Zhang, Jingna Xun, Rong Zhang, Youhua Xie, Shibo Jiang, Tongyu Zhu, Hongzhou Lu, Yumei Wen, Jinghe Huang, 2020 Self-assembly M2e-based peptide nanovaccine confers cross-protection against influenza viruses, Qimin Wang, Yuling Zhang, Peng Zou, Meixiang Wang, Weihui Fu, Jialei She, Zhigang Song, Jianqing Xu, Jinghe Huang, Fan Wu, 2020 Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine, Matsuda K, Huang J, Zhou T, Sheng Z, Kang BH, Ishida E, Griesman T, Stuccio S, Bolkhovitinov L, Wohlbold TJ, Chromikova V, Cagigi A, Leung K, Andrews S, Cheung CSF, Pullano AA, Plyler J, Soto C, Zhang B, Yang Y, Joyce MG, Tsybovsky Y, Wheatley A, Narpala SR, Guo Y, Darko S, Bailer RT, Poole A, Liang CJ, Smith J, Alexander J, Gurwith M, Migueles SA, Koup RA, Golding H, Khurana S, McDermott AB, Shapiro L, Krammer F, Kwong PD, Connors M, 2019 Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth, Huang J, Kang BH, Ishida E, Zhou T, Griesman T, Sheng Z, Wu F, Doria-Rose NA, Zhang B, McKee K, O'Dell S, Chuang GY, Druz A, Georgiev IS, Schramm CA, Zheng A, Joyce MG, Asokan M, Ransier A, Darko S, Migueles SA, Bailer RT, Louder MK, Alam SM, Parks R, Kelsoe G, Von Holle T, Haynes BF, Douek DC, Hirsch V, Seaman MS, Shapiro L, Mascola JR, Kwong PD, Connors M, 2016 Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-120 interface, Huang J, Kang B, Pancera M, Lee JH, Tong T, Feng Y, Imamichi H, Georgiev I, Chuang GY, Druz A, Doria-Rose NA, Laub L, Sliepen K, van Gils M, de la Peña AT, Derking R, Klasse PJ, Migueles SA, Bailer RT, Alam SM, Pugach P, Haynes BF, Wyatt RT, Sanders RW, Binley JM, Ward AB, Mascola JR, Kwong PD, Connors M, 2014 Isolation of human monoclonal antibodies from peripheral blood B cells, Huang J, Doria-Rose NA, Longo NS, Laub L, Lin CL, Turk E, Kang B, Migueles SA, Bailer RT, Mascola JR, Connors M, 2013 Broad and potent neutralization of HIV-1 by a gp41-specific human antibody, Huang J, Ofek G, Laub L, Louder MK, Doria-Rose NA, Longo NS, Imamichi H, Bailer RT, Chakrabarti B, Sharma SK, Alam SM, Wang T, Yang Y, Zhang B, Migueles SA, Wyratt R, Haynes BF, Kwong PD, Mascola JR, Connors M, 2012

Areas of Focus

Development and neutralization mechanism of broad-spectrum antiviral neutralizing antibody drugs
Biotherapeutic applications of broad-spectrum antiviral neutralizing antibodies
Research on prevention and control strategies for emerging infectious diseases

Publications

Novel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and sarbecoviruses, Yingdan Wang, Meiqin Liu, Yaping Shen, Yunping Ma, Xiang Li, Yuanyuan Zhang, Xing-Lou Yang, Mei Liu, Jun Chen, Renhong Yan, Die Luan, Yanqun Wang, Ying Chen, Qimin Wang, Haofeng Lin, Yaning Li, Kaiyue Wu, Tongyu Zhu, Jincun Zhao, Hongzhou Lu, Yumei Wen, Shibo Jiang, Fan Wu, Qiang Zhou, Zheng-Li Shi, Jinghe Huang, 2022
Resistance of SARS-CoV-2 Omicron Variant to Convalescent and CoronaVac Vaccine Plasma, Yingdan Wang, Yunping Ma, Yan Xu, Jiangyan Liu, Xiang Li, Yuyuan Chen, Yan Chen, Jun Xie, Lianbo Xiao, Zheng Xiang, Fan Wu, Jinghe Huang, 2022
Tetrameric NA of Influenza A virus is required to induce protective antibody responses in mice, Xiren Deng, Qimin Wang, Mei Liu, Qinwen Zheng, Fan Wu, Jinghe Huang, 2021
Evaluating the Association of Clinical Characteristics With Neutralizing Antibody Levels in Patients Who Have Recovered From Mild COVID-19 in Shanghai, China, Fan Wu, Mei Liu, Aojie Wang, Lu Lu, Qimin Wang, Chenjian Gu, Jun Chen, Yang Wu, Shuai Xia, Yun Ling, Yuling, Zhang, Jingna Xun, Rong Zhang, Youhua Xie, Shibo Jiang, Tongyu Zhu, Hongzhou Lu, Yumei Wen, Jinghe Huang, 2020
Self-assembly M2e-based peptide nanovaccine confers cross-protection against influenza viruses, Qimin Wang, Yuling Zhang, Peng Zou, Meixiang Wang, Weihui Fu, Jialei She, Zhigang Song, Jianqing Xu, Jinghe Huang, Fan Wu, 2020
Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine, Matsuda K, Huang J, Zhou T, Sheng Z, Kang BH, Ishida E, Griesman T, Stuccio S, Bolkhovitinov L, Wohlbold TJ, Chromikova V, Cagigi A, Leung K, Andrews S, Cheung CSF, Pullano AA, Plyler J, Soto C, Zhang B, Yang Y, Joyce MG, Tsybovsky Y, Wheatley A, Narpala SR, Guo Y, Darko S, Bailer RT, Poole A, Liang CJ, Smith J, Alexander J, Gurwith M, Migueles SA, Koup RA, Golding H, Khurana S, McDermott AB, Shapiro L, Krammer F, Kwong PD, Connors M, 2019
Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth, Huang J, Kang BH, Ishida E, Zhou T, Griesman T, Sheng Z, Wu F, Doria-Rose NA, Zhang B, McKee K, O'Dell S, Chuang GY, Druz A, Georgiev IS, Schramm CA, Zheng A, Joyce MG, Asokan M, Ransier A, Darko S, Migueles SA, Bailer RT, Louder MK, Alam SM, Parks R, Kelsoe G, Von Holle T, Haynes BF, Douek DC, Hirsch V, Seaman MS, Shapiro L, Mascola JR, Kwong PD, Connors M, 2016
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-120 interface, Huang J, Kang B, Pancera M, Lee JH, Tong T, Feng Y, Imamichi H, Georgiev I, Chuang GY, Druz A, Doria-Rose NA, Laub L, Sliepen K, van Gils M, de la Peña AT, Derking R, Klasse PJ, Migueles SA, Bailer RT, Alam SM, Pugach P, Haynes BF, Wyatt RT, Sanders RW, Binley JM, Ward AB, Mascola JR, Kwong PD, Connors M, 2014
Isolation of human monoclonal antibodies from peripheral blood B cells, Huang J, Doria-Rose NA, Longo NS, Laub L, Lin CL, Turk E, Kang B, Migueles SA, Bailer RT, Mascola JR, Connors M, 2013
Broad and potent neutralization of HIV-1 by a gp41-specific human antibody, Huang J, Ofek G, Laub L, Louder MK, Doria-Rose NA, Longo NS, Imamichi H, Bailer RT, Chakrabarti B, Sharma SK, Alam SM, Wang T, Yang Y, Zhang B, Migueles SA, Wyratt R, Haynes BF, Kwong PD, Mascola JR, Connors M, 2012

Antiviral Neutralizing Antibody Broad-Spectrum Drug Development Neutralization Mechanism Biotherapy Emerging Diseases Prevention Control Strategies Infectious Diseases

Yihong Peng - Peking University

Ying Wu - Wuhan University

Wu Yan - Capital Medical University

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