Professor | Ming-Wei Wang | Asia Growth Partners

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Name	Ming-Wei Wang
Contact Information	mwwang@simm.ac.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Ming-Wei Wang

Contact Information

mwwang@simm.ac.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1978.02—1982.12 Bachelor's Degree in Medicine: Shanghai First Medical College 1986.10—1989.11 PhD in Physiology: University of Cambridge
Work Experience	1983.01—1984.06 - Shanghai Sixth People's Hospital - Resident Orthopedic Surgeon 1984.07—1985.09 - University of California, Los Angeles - Visiting Scholar 1985.10—1986.09 - University of Cambridge, Institute of Animal Physiology - Visiting Scholar 1989.12—1990.05 - University of Cambridge, School of Medicine - Senior Research Assistant 1990.06—1992.07 - Amylin Pharmaceuticals - Researcher 1992.08—1996.07 - Ligand Pharmaceuticals - Research Supervisor 1996.08—1997.12 - GC Biotech - Director 1998.01—2000.06 - Shanghai Jikang Biotechnology Co., Ltd. - Chairman and General Manager 2000.07—2001.11 - Ansell Pharmaceuticals - Vice Chairman 2001.12—2021.12 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher (Second Level) 2003.08—2021.12 - National Center for Drug Screening - Director 2012.01—2021.12 - National Compound Sample Library - Director 2015.01—Present - ShanghaiTech University, School of Life Science and Technology - Distinguished Professor 2015.10—2021.01 - Fudan University, School of Pharmacy - Dean 2022.04—Present - University of Tokyo, School of Science, Department of Chemistry - Visiting Professor
Awards	2002: Selected for the Chinese Academy of Sciences 'Hundred Talents Program' 2005: Awarded the State Council Special Allowance 2002: Shanghai 'Magnolia Memorial Award' 2002: Shanghai Science and Technology Progress Award (First Prize) 2003: National Science and Technology Progress Award (Second Prize) 2012: Shanghai 'Magnolia Honor Award' 2012: National Outstanding Scientific and Technological Worker 2014: Pudong New Area Science and Technology Progress Award (First Prize) 2020: Shanghai Natural Science Award (First Prize)

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1978.02—1982.12 Bachelor's Degree in Medicine: Shanghai First Medical College
1986.10—1989.11 PhD in Physiology: University of Cambridge

Work Experience

1983.01—1984.06 - Shanghai Sixth People's Hospital - Resident Orthopedic Surgeon
1984.07—1985.09 - University of California, Los Angeles - Visiting Scholar
1985.10—1986.09 - University of Cambridge, Institute of Animal Physiology - Visiting Scholar
1989.12—1990.05 - University of Cambridge, School of Medicine - Senior Research Assistant
1990.06—1992.07 - Amylin Pharmaceuticals - Researcher
1992.08—1996.07 - Ligand Pharmaceuticals - Research Supervisor
1996.08—1997.12 - GC Biotech - Director
1998.01—2000.06 - Shanghai Jikang Biotechnology Co., Ltd. - Chairman and General Manager
2000.07—2001.11 - Ansell Pharmaceuticals - Vice Chairman
2001.12—2021.12 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher (Second Level)
2003.08—2021.12 - National Center for Drug Screening - Director
2012.01—2021.12 - National Compound Sample Library - Director
2015.01—Present - ShanghaiTech University, School of Life Science and Technology - Distinguished Professor
2015.10—2021.01 - Fudan University, School of Pharmacy - Dean
2022.04—Present - University of Tokyo, School of Science, Department of Chemistry - Visiting Professor

Awards

2002: Selected for the Chinese Academy of Sciences 'Hundred Talents Program'
2005: Awarded the State Council Special Allowance
2002: Shanghai 'Magnolia Memorial Award'
2002: Shanghai Science and Technology Progress Award (First Prize)
2003: National Science and Technology Progress Award (Second Prize)
2012: Shanghai 'Magnolia Honor Award'
2012: National Outstanding Scientific and Technological Worker
2014: Pudong New Area Science and Technology Progress Award (First Prize)
2020: Shanghai Natural Science Award (First Prize)

Areas of Focus	New Drug Screening and Basic Pharmacology Research
Publications	Structure of the human glucagon class B G-protein-coupled receptor, Fai Yiu Siu, Min He, Chris de Graaf, Gye Won Han, Dehua Yang, Zhiyun Zhang, Caihong Zhou, Qingping Xu, Daniel Wacker, Jeremiah S. Joseph, Wei Liu, Jesper Lau, Vadim Cherezov, Vsevolod Katritch, Ming-Wei Wang and Raymond C. Stevens, 2013 Structure of the full-length glucagon class B G-protein-coupled receptor, Haonan Zhang, Anna Qiao, Dehua Yang, Linlin Yang, Antao Dai, Chris de Graaf, Steffen Reedtz-Runge, Venkatasubramanian Dharmarajan, Hui Zhang, Gye Won Han, Thomas D. Grant, Raymond G. Sierra, Uwe Weierstall, Garrett Nelson, Wei Liu, Yanhong Wu, Limin Ma, Xiaoqing Cai, Guangyao Lin, Xiaoai Wu, Zhi Geng, Yuhui Dong, Gaojie Song, Patrick R. Griffin, Jesper Lau, Vadim Cherezov, Huaiyu Yang, Michael A. Hanson, Raymond C. Stevens, Qiang Zhao, Hualiang Jiang, Ming-Wei Wang and Beili Wu, 2017 Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators, Gaojie Song, Dehua Yang, Yuxia Wang, Chris de Graaf, Qingtong Zhou, Shanshan Jiang, Kaiwen Liu, Xiaoqing Cai, Antao Dai, Guangyao Lin, Dongsheng Liu, Fan Wu, Yiran Wu, Suwen Zhao, Li Ye, Gye Won Han, Jesper Lau, Beili Wu, Michael A. Hanson, Zhi-Jie Liu, Ming-Wei Wang and Raymond C. Stevens, 2017 Structure and dynamics of the active human parathyroid hormone receptor-1, Li-Hua Zhao, Shanshan Ma, Ieva Sutkeviciute, Dan-Dan Shen, X. Edward Zhou, Parker W. de Waal, Chen-Yao Li, Yanyong Kang, Lisa J. Clark, Frederic G. Jean-Alphonse, Alex D. White, Dehua Yang, Antao Dai, Xiaoqing Cai, Jian Chen, Cong Li, Yi Jiang, Tomoyuki Watanabe, Thomas J. Gardella, Karsten Melcher, Ming-Wei Wang, Jean-Pierre Vilardaga, H. Eric Xu and Yan Zhang, 2019 Structural basis for activation of the growth hormone-releasing hormone receptor, Fulai Zhou, Huibing Zhang, Zhaotong Cong, Li-Hua Zhao, Qingtong Zhou, Chunyou Mao, Xi Cheng, Dan-Dan Shen, Xiaoqing Cai, Cheng Ma, Yuzhe Wang, Antao Dai, Yan Zhou, Wen Sun, Fenghui Zhao, Suwen Zhao, Hualiang Jiang, Yi Jiang, Dehua Yang, H. Eric Xu, Yan Zhang and Ming-Wei Wang, 2020 A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor, Wen Sun, Li-Nan Chen, Qingtong Zhou, Li-Hua Zhao, Dehua Yang, Huibing Zhang, Zhaotong Cong, Dan-Dan Shen, Fenghui Zhao, Fulai Zhou, Xiaoqing Cai, Yan Chen, Yan Zhou, Sarina Gadgaard, Wijnand J. C. van der Velden, Suwen Zhao, Yi Jiang, Mette M Rosenkilde, H. Eric Xu, Yan Zhang and Ming-Wei Wang, 2020 Structures of Gi-bound metabotropic glutamate receptors mGluR2 and mGluR4, Shuling Lin, Shuo Han, Xiaoqing Cai, Qiuxiang Tan, Kexiu Zhou, Dejian Wang, Xinwei Wang, Juan Du, Cuiying Yi, Xiaojing Chu, Antao Dai, Yan Zhou, Yan Chen, Yu Zhou, Hong Liu, Jianfeng Liu, Dehua Yang, Ming-Wei Wang, Qiang Zhao and Beili Wu, 2021 Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor, Zhaotong Cong, Li-Nan Chen, Honglei Ma, Qingtong Zhou, Xinyu Zou, Chenyu Ye, Antao Dai, Qing Liu, Wei Huang, Xianqiang Sun, Xi Wang, Peiyu Xu, Lihua Zhao, Tian Xia, Wenge Zhong, Dehua Yang, H. Eric Xu, Yan Zhang and Ming-Wei Wang, 2021 Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2, Xi Wang, Xi Cheng, Lihua Zhao, Yuzhe Wang, Chenyu Ye, Xinyu Zou, Antao Dai, Zhaotong Cong, Jian Chen, Qingtong Zhou, Tian Xia, Hualiang Jiang, H. Eric Xu, Dehua Yang and Ming-Wei Wang, 2021 Constitutive signal bias mediated by the human GHRHR splice variant 1, Zhaotong Cong, Fulai Zhou, Chao Zhang, Xinyu Zou, Huibing Zhang, Yuzhe Wang, Qingtong Zhou, Xiaoqing Cai, Qiaofeng Liu, Jie Li, Lijun Shao, Chunyou Mao, Xi Wang, Jihong Wu, Tian Xia, Li-hua Zhao, Hualiang Jiang, H. Eric Xu, Xi Cheng, Dehua Yang and Ming-Wei Wang, 2021

Areas of Focus

New Drug Screening and Basic Pharmacology Research

Publications

Structure of the human glucagon class B G-protein-coupled receptor, Fai Yiu Siu, Min He, Chris de Graaf, Gye Won Han, Dehua Yang, Zhiyun Zhang, Caihong Zhou, Qingping Xu, Daniel Wacker, Jeremiah S. Joseph, Wei Liu, Jesper Lau, Vadim Cherezov, Vsevolod Katritch, Ming-Wei Wang and Raymond C. Stevens, 2013
Structure of the full-length glucagon class B G-protein-coupled receptor, Haonan Zhang, Anna Qiao, Dehua Yang, Linlin Yang, Antao Dai, Chris de Graaf, Steffen Reedtz-Runge, Venkatasubramanian Dharmarajan, Hui Zhang, Gye Won Han, Thomas D. Grant, Raymond G. Sierra, Uwe Weierstall, Garrett Nelson, Wei Liu, Yanhong Wu, Limin Ma, Xiaoqing Cai, Guangyao Lin, Xiaoai Wu, Zhi Geng, Yuhui Dong, Gaojie Song, Patrick R. Griffin, Jesper Lau, Vadim Cherezov, Huaiyu Yang, Michael A. Hanson, Raymond C. Stevens, Qiang Zhao, Hualiang Jiang, Ming-Wei Wang and Beili Wu, 2017
Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators, Gaojie Song, Dehua Yang, Yuxia Wang, Chris de Graaf, Qingtong Zhou, Shanshan Jiang, Kaiwen Liu, Xiaoqing Cai, Antao Dai, Guangyao Lin, Dongsheng Liu, Fan Wu, Yiran Wu, Suwen Zhao, Li Ye, Gye Won Han, Jesper Lau, Beili Wu, Michael A. Hanson, Zhi-Jie Liu, Ming-Wei Wang and Raymond C. Stevens, 2017
Structure and dynamics of the active human parathyroid hormone receptor-1, Li-Hua Zhao, Shanshan Ma, Ieva Sutkeviciute, Dan-Dan Shen, X. Edward Zhou, Parker W. de Waal, Chen-Yao Li, Yanyong Kang, Lisa J. Clark, Frederic G. Jean-Alphonse, Alex D. White, Dehua Yang, Antao Dai, Xiaoqing Cai, Jian Chen, Cong Li, Yi Jiang, Tomoyuki Watanabe, Thomas J. Gardella, Karsten Melcher, Ming-Wei Wang, Jean-Pierre Vilardaga, H. Eric Xu and Yan Zhang, 2019
Structural basis for activation of the growth hormone-releasing hormone receptor, Fulai Zhou, Huibing Zhang, Zhaotong Cong, Li-Hua Zhao, Qingtong Zhou, Chunyou Mao, Xi Cheng, Dan-Dan Shen, Xiaoqing Cai, Cheng Ma, Yuzhe Wang, Antao Dai, Yan Zhou, Wen Sun, Fenghui Zhao, Suwen Zhao, Hualiang Jiang, Yi Jiang, Dehua Yang, H. Eric Xu, Yan Zhang and Ming-Wei Wang, 2020
A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor, Wen Sun, Li-Nan Chen, Qingtong Zhou, Li-Hua Zhao, Dehua Yang, Huibing Zhang, Zhaotong Cong, Dan-Dan Shen, Fenghui Zhao, Fulai Zhou, Xiaoqing Cai, Yan Chen, Yan Zhou, Sarina Gadgaard, Wijnand J. C. van der Velden, Suwen Zhao, Yi Jiang, Mette M Rosenkilde, H. Eric Xu, Yan Zhang and Ming-Wei Wang, 2020
Structures of Gi-bound metabotropic glutamate receptors mGluR2 and mGluR4, Shuling Lin, Shuo Han, Xiaoqing Cai, Qiuxiang Tan, Kexiu Zhou, Dejian Wang, Xinwei Wang, Juan Du, Cuiying Yi, Xiaojing Chu, Antao Dai, Yan Zhou, Yan Chen, Yu Zhou, Hong Liu, Jianfeng Liu, Dehua Yang, Ming-Wei Wang, Qiang Zhao and Beili Wu, 2021
Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor, Zhaotong Cong, Li-Nan Chen, Honglei Ma, Qingtong Zhou, Xinyu Zou, Chenyu Ye, Antao Dai, Qing Liu, Wei Huang, Xianqiang Sun, Xi Wang, Peiyu Xu, Lihua Zhao, Tian Xia, Wenge Zhong, Dehua Yang, H. Eric Xu, Yan Zhang and Ming-Wei Wang, 2021
Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2, Xi Wang, Xi Cheng, Lihua Zhao, Yuzhe Wang, Chenyu Ye, Xinyu Zou, Antao Dai, Zhaotong Cong, Jian Chen, Qingtong Zhou, Tian Xia, Hualiang Jiang, H. Eric Xu, Dehua Yang and Ming-Wei Wang, 2021
Constitutive signal bias mediated by the human GHRHR splice variant 1, Zhaotong Cong, Fulai Zhou, Chao Zhang, Xinyu Zou, Huibing Zhang, Yuzhe Wang, Qingtong Zhou, Xiaoqing Cai, Qiaofeng Liu, Jie Li, Lijun Shao, Chunyou Mao, Xi Wang, Jihong Wu, Tian Xia, Li-hua Zhao, Hualiang Jiang, H. Eric Xu, Xi Cheng, Dehua Yang and Ming-Wei Wang, 2021

Drug Screening Pharmacology New Drugs Basic Research Pharmaceuticals Biotechnology Cancer Therapeutics Molecular Biology Genomics

Xuetao Cao - Zhejiang University

Cai-Ping Ren - Central South University

Zhou Jing - Zhejiang University

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