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Ming-Wei Wang
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, English
Drug Screening
Pharmacology
New Drugs
Basic Research
Pharmaceuticals
Biotechnology
Cancer
Therapeutics
Molecular Biology
Genomics
Areas of Focus
- New Drug Screening and Basic Pharmacology Research
Work Experience
- 1983.01—1984.06 - Shanghai Sixth People's Hospital - Resident Orthopedic Surgeon
- 1984.07—1985.09 - University of California, Los Angeles - Visiting Scholar
- 1985.10—1986.09 - University of Cambridge, Institute of Animal Physiology - Visiting Scholar
- 1989.12—1990.05 - University of Cambridge, School of Medicine - Senior Research Assistant
- 1990.06—1992.07 - Amylin Pharmaceuticals - Researcher
- 1992.08—1996.07 - Ligand Pharmaceuticals - Research Supervisor
- 1996.08—1997.12 - GC Biotech - Director
- 1998.01—2000.06 - Shanghai Jikang Biotechnology Co., Ltd. - Chairman and General Manager
- 2000.07—2001.11 - Ansell Pharmaceuticals - Vice Chairman
- 2001.12—2021.12 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher (Second Level)
- 2003.08—2021.12 - National Center for Drug Screening - Director
- 2012.01—2021.12 - National Compound Sample Library - Director
- 2015.01—Present - ShanghaiTech University, School of Life Science and Technology - Distinguished Professor
- 2015.10—2021.01 - Fudan University, School of Pharmacy - Dean
- 2022.04—Present - University of Tokyo, School of Science, Department of Chemistry - Visiting Professor
Academic Background & Achievements
- 1978.02—1982.12 Bachelor's Degree in Medicine: Shanghai First Medical College
- 1986.10—1989.11 PhD in Physiology: University of Cambridge
Publications
- Structure of the human glucagon class B G-protein-coupled receptor, Fai Yiu Siu, Min He, Chris de Graaf, Gye Won Han, Dehua Yang, Zhiyun Zhang, Caihong Zhou, Qingping Xu, Daniel Wacker, Jeremiah S. Joseph, Wei Liu, Jesper Lau, Vadim Cherezov, Vsevolod Katritch, Ming-Wei Wang and Raymond C. Stevens, 2013
- Structure of the full-length glucagon class B G-protein-coupled receptor, Haonan Zhang, Anna Qiao, Dehua Yang, Linlin Yang, Antao Dai, Chris de Graaf, Steffen Reedtz-Runge, Venkatasubramanian Dharmarajan, Hui Zhang, Gye Won Han, Thomas D. Grant, Raymond G. Sierra, Uwe Weierstall, Garrett Nelson, Wei Liu, Yanhong Wu, Limin Ma, Xiaoqing Cai, Guangyao Lin, Xiaoai Wu, Zhi Geng, Yuhui Dong, Gaojie Song, Patrick R. Griffin, Jesper Lau, Vadim Cherezov, Huaiyu Yang, Michael A. Hanson, Raymond C. Stevens, Qiang Zhao, Hualiang Jiang, Ming-Wei Wang and Beili Wu, 2017
- Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators, Gaojie Song, Dehua Yang, Yuxia Wang, Chris de Graaf, Qingtong Zhou, Shanshan Jiang, Kaiwen Liu, Xiaoqing Cai, Antao Dai, Guangyao Lin, Dongsheng Liu, Fan Wu, Yiran Wu, Suwen Zhao, Li Ye, Gye Won Han, Jesper Lau, Beili Wu, Michael A. Hanson, Zhi-Jie Liu, Ming-Wei Wang and Raymond C. Stevens, 2017
- Structure and dynamics of the active human parathyroid hormone receptor-1, Li-Hua Zhao, Shanshan Ma, Ieva Sutkeviciute, Dan-Dan Shen, X. Edward Zhou, Parker W. de Waal, Chen-Yao Li, Yanyong Kang, Lisa J. Clark, Frederic G. Jean-Alphonse, Alex D. White, Dehua Yang, Antao Dai, Xiaoqing Cai, Jian Chen, Cong Li, Yi Jiang, Tomoyuki Watanabe, Thomas J. Gardella, Karsten Melcher, Ming-Wei Wang, Jean-Pierre Vilardaga, H. Eric Xu and Yan Zhang, 2019
- Structural basis for activation of the growth hormone-releasing hormone receptor, Fulai Zhou, Huibing Zhang, Zhaotong Cong, Li-Hua Zhao, Qingtong Zhou, Chunyou Mao, Xi Cheng, Dan-Dan Shen, Xiaoqing Cai, Cheng Ma, Yuzhe Wang, Antao Dai, Yan Zhou, Wen Sun, Fenghui Zhao, Suwen Zhao, Hualiang Jiang, Yi Jiang, Dehua Yang, H. Eric Xu, Yan Zhang and Ming-Wei Wang, 2020
- A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor, Wen Sun, Li-Nan Chen, Qingtong Zhou, Li-Hua Zhao, Dehua Yang, Huibing Zhang, Zhaotong Cong, Dan-Dan Shen, Fenghui Zhao, Fulai Zhou, Xiaoqing Cai, Yan Chen, Yan Zhou, Sarina Gadgaard, Wijnand J. C. van der Velden, Suwen Zhao, Yi Jiang, Mette M Rosenkilde, H. Eric Xu, Yan Zhang and Ming-Wei Wang, 2020
- Structures of Gi-bound metabotropic glutamate receptors mGluR2 and mGluR4, Shuling Lin, Shuo Han, Xiaoqing Cai, Qiuxiang Tan, Kexiu Zhou, Dejian Wang, Xinwei Wang, Juan Du, Cuiying Yi, Xiaojing Chu, Antao Dai, Yan Zhou, Yan Chen, Yu Zhou, Hong Liu, Jianfeng Liu, Dehua Yang, Ming-Wei Wang, Qiang Zhao and Beili Wu, 2021
- Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor, Zhaotong Cong, Li-Nan Chen, Honglei Ma, Qingtong Zhou, Xinyu Zou, Chenyu Ye, Antao Dai, Qing Liu, Wei Huang, Xianqiang Sun, Xi Wang, Peiyu Xu, Lihua Zhao, Tian Xia, Wenge Zhong, Dehua Yang, H. Eric Xu, Yan Zhang and Ming-Wei Wang, 2021
- Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2, Xi Wang, Xi Cheng, Lihua Zhao, Yuzhe Wang, Chenyu Ye, Xinyu Zou, Antao Dai, Zhaotong Cong, Jian Chen, Qingtong Zhou, Tian Xia, Hualiang Jiang, H. Eric Xu, Dehua Yang and Ming-Wei Wang, 2021
- Constitutive signal bias mediated by the human GHRHR splice variant 1, Zhaotong Cong, Fulai Zhou, Chao Zhang, Xinyu Zou, Huibing Zhang, Yuzhe Wang, Qingtong Zhou, Xiaoqing Cai, Qiaofeng Liu, Jie Li, Lijun Shao, Chunyou Mao, Xi Wang, Jihong Wu, Tian Xia, Li-hua Zhao, Hualiang Jiang, H. Eric Xu, Xi Cheng, Dehua Yang and Ming-Wei Wang, 2021
Awards
- 2002: Selected for the Chinese Academy of Sciences 'Hundred Talents Program'
- 2005: Awarded the State Council Special Allowance
- 2002: Shanghai 'Magnolia Memorial Award'
- 2002: Shanghai Science and Technology Progress Award (First Prize)
- 2003: National Science and Technology Progress Award (Second Prize)
- 2012: Shanghai 'Magnolia Honor Award'
- 2012: National Outstanding Scientific and Technological Worker
- 2014: Pudong New Area Science and Technology Progress Award (First Prize)
- 2020: Shanghai Natural Science Award (First Prize)
