Professor | Ji-Yang Wang | Asia Growth Partners

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Name	Ji-Yang Wang
Contact Information	wang@fudan.edu.cn
Language ability	Japanese, English, Chinese
Province	Shanghai

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Name

Ji-Yang Wang

Contact Information

wang@fudan.edu.cn

Language ability

Japanese, English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1980/04-1984/03 Bachelor: Hiroshima University, Japan 1984/04-1986/03 Master: Kwansei Gakuin University, Japan 1986/04-1990/03 PhD: Kyushu University, Japan
Work Experience	1990/04-1998/09 - Kyushu University - Assistant Professor 1991/10-1994/09 - University of Alabama - Research Assistant 1997/04-1997/09 - Harvard Medical School - Visiting Scholar 1998/10-2003/02 - Chiba Cancer Center - Chief Researcher 2003/03-2013/03 - RIKEN Research Center for Allergy and Immunology - Laboratory Head 2014/04-Present - Fudan University - Professor
Awards	Asahi Science and Technology Award (1987): Detail Ito Research Award (1990): Detail Chiba Cancer Center Research Award (2000): Detail RIKEN International Cooperation Award (2004): Detail RIKEN Excellent Paper Award (2009): Detail

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1980/04-1984/03 Bachelor: Hiroshima University, Japan
1984/04-1986/03 Master: Kwansei Gakuin University, Japan
1986/04-1990/03 PhD: Kyushu University, Japan

Work Experience

1990/04-1998/09 - Kyushu University - Assistant Professor
1991/10-1994/09 - University of Alabama - Research Assistant
1997/04-1997/09 - Harvard Medical School - Visiting Scholar
1998/10-2003/02 - Chiba Cancer Center - Chief Researcher
2003/03-2013/03 - RIKEN Research Center for Allergy and Immunology - Laboratory Head
2014/04-Present - Fudan University - Professor

Awards

Asahi Science and Technology Award (1987): Detail
Ito Research Award (1990): Detail
Chiba Cancer Center Research Award (2000): Detail
RIKEN International Cooperation Award (2004): Detail
RIKEN Excellent Paper Award (2009): Detail

Areas of Focus	Regulation mechanisms of humoral immunity and immune tolerance Regulation of intestinal secretion of IgA and its role in inflammatory bowel disease and colorectal cancer Cellular and molecular mechanisms of antibody deficiency diseases
Publications	RAG1 splicing mutation causes enhanced B-cell differentiation and autoantibody production, Min, Q., Meng, X., Zhou, Q., Wang, Y., Li, Y., Lai, N., Xiong, E., Wang, W., Yasuda, S., Yu, M., Zhang, H., Sun, J., Wang, X.#, Wang, J.-Y.#, 2021 Effective and safe treatment of a novel IL2RA deficiency with rapamycin, Lai, N., Liu, L., Lin, L., Cui, C., Wang, Y., Min, Q., Xiong, E., Wang, W., Ying, W., Zhou, Q., Hou, J., Sun, J., Wang, J.-Y.#, and Wang, X., 2020 MZB1 promotes the secretion of J chain-containing dimeric IgA and is critical for the suppression of gut inflammation, Xiong, E., Li, Y., Min, Q., Cui, C., Liu, J., Hong, R., Lai, N., Wang, Y., Sun, J., Matsumoto, R., Takahashi, D., Hase, K., Shinkura, R., Tsubata, T. and Wang, J.-Y.#, 2019 EAF2 mediates germinal centre B-cell apoptosis to suppress excessive immune responses and prevent autoimmunity, Li, Y.*, Takahashi, Y., Fujii, S., Zhou, Y., Hong, R., Suzuki, A., Tsubata, T., Hase, K.#, Wang, J.-Y.#, 2016 Critical role of the IgM Fc receptor in IgM homeostasis, B cell survival and humoral immune responses, Ouchida, R., Mori, H., Hase, K., Takatsu, H., Kurosaki, T., Tokuhisa, T., Ohno, H. and Wang, J.-Y.#, 2012

Areas of Focus

Regulation mechanisms of humoral immunity and immune tolerance
Regulation of intestinal secretion of IgA and its role in inflammatory bowel disease and colorectal cancer
Cellular and molecular mechanisms of antibody deficiency diseases

Publications

RAG1 splicing mutation causes enhanced B-cell differentiation and autoantibody production, Min, Q.*, Meng, X.*, Zhou, Q.*, Wang, Y., Li, Y., Lai, N., Xiong, E., Wang, W., Yasuda, S., Yu, M., Zhang, H., Sun, J., Wang, X.#, Wang, J.-Y.#, 2021
Effective and safe treatment of a novel IL2RA deficiency with rapamycin, Lai, N.*, Liu, L.*, Lin, L., Cui, C., Wang, Y., Min, Q., Xiong, E., Wang, W., Ying, W., Zhou, Q., Hou, J., Sun, J., Wang, J.-Y.#, and Wang, X., 2020
MZB1 promotes the secretion of J chain-containing dimeric IgA and is critical for the suppression of gut inflammation, Xiong, E.*, Li, Y.*, Min, Q.*, Cui, C., Liu, J., Hong, R., Lai, N., Wang, Y., Sun, J., Matsumoto, R., Takahashi, D., Hase, K., Shinkura, R., Tsubata, T. and Wang, J.-Y.#, 2019
EAF2 mediates germinal centre B-cell apoptosis to suppress excessive immune responses and prevent autoimmunity, Li, Y.*, Takahashi, Y., Fujii, S., Zhou, Y., Hong, R., Suzuki, A., Tsubata, T., Hase, K.#, Wang, J.-Y.#, 2016
Critical role of the IgM Fc receptor in IgM homeostasis, B cell survival and humoral immune responses, Ouchida, R., Mori, H., Hase, K., Takatsu, H., Kurosaki, T., Tokuhisa, T., Ohno, H. and Wang, J.-Y.#, 2012

Humoral Immunity Immune Tolerance Iga Intestinal Secretion Inflammatory Bowel Disease Colorectal Cancer Antibody Deficiency Cellular Mechanisms Molecular Mechanisms Immune Regulation

Yong Zhou - Central South University

Hongguang Xia - Zhejiang University

Weilin Hu - Zhejiang University

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