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Ruizhe Qian
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, Japanese
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Biological Rhythms Regulation Mechanisms Disorders Diseases Aging Circadian Clock Genes Mitochondria Homeostasis
Areas of Focus
  • Regulation Mechanisms of Biological Rhythms
  • Biological Rhythm Disorders and Diseases
  • Biological Rhythms and Aging
Work Experience
  • 1987.07—Present - Fudan University - Assistant, Lecturer, Associate Professor, Professor
Academic Background & Achievements
  • 1981.09—1987.07 Bachelor's in Clinical Medicine: Shanghai Medical University
  • 2001.04—2003.11 PhD in Medicine: Showa University, Japan
Publications
  • CLOCK regulates Drp1 mRNA stability and mitochondrial homeostasis by interacting with PUF60, Lirong Xu, Jiaxin Lin, Yutong Liu, Bingxuan Hua, Qianyun Cheng, Changpo Lin, Zuoqin Yan, Yaping Wang, Ning Sun, Ruizhe Qian, Chao Lu, 2022
  • miR-455-5p regulates circadian rhythms by accelerating the degradation of Clock mRNA, Qianyun Cheng, Xinyi Fan, Yutong Liu, Lirong Xu, Pengjuan Dong, Liwen Song, Ruizhe Qian, 2022
  • Clock Gene Bmal1 Disruption in Vascular Smooth Muscle Cells Worsens Carotid Atherosclerotic Lesions, Changpo Lin, Lirong Xu, Xiao Tang, Xiaobo Li, Chao Lu, Qianyun Cheng, Junhao Jiang, Yang Shen, Dong Yan, Ruizhe Qian, Weiguo Fu, Daqiao Guo, 2022
  • Identification of potential therapeutic targets for atherosclerosis by analysing the gene signature related to different immune cells and immune regulators in atheromatous plaques, Yang Shen, Li-Rong Xu, Xiao Tang, Chang-Po Lin, Dong Yan, Song Xue, Rui-Zhe Qian, Da-Qiao Guo, 2021
  • BMAL1 regulates mitochondrial fission and mitophagy through mitochondrial protein BNIP3 and is critical in the development of dilated cardiomyopathy, Ermin Li, Xiuya Li, Jie Huang, Chen Xu, Qianqian Liang, Kehan Ren, Aobing Bai, Chao Lu, Ruizhe Qian, Ning Sun, 2020
  • Clock mutant promotes osteoarthritis by inhibiting the acetylation of NFκB, Gongsheng Yuan, Lirong Xu, Tingting Cai, Bingxuan Hua, Ning Sun, Zuoqin Yan, Chao Lu, Ruizhe Qian, 2019
  • Clock represses preadipocytes adipogenesis via GILZ, Zhu Zhu, Lirong Xu, Tingting Cai, Gongsheng Yuan, Ning Sun, Chao Lu, Qian Ruizhe, 2018
  • Clock mediates liver senescence by controlling ER stress, Gongsheng Yuan, Bingxuan Hua, Ermin Li, Lirong Xu, Tingting Cai, Yiqing Huang, Ning Sun, Zuoqin Yan, Chao Lu, Qian Ruizhe, 2017
  • The circadian gene Clock regulates bone formation via PDIA3, Gongsheng Yuan, Bingxuan Hua, Yang Yang, Lirong Xu, Tingting Cai, Ning Sun, Zuoqin Yan, Chao Lu, Qian Ruizhe, 2017
  • Role of circadian gene Clock during differentiation of mouse pluripotent stem cells, Lu Chao, Yang Yang, Ran Zhao, Bingxuan Hua, Chen Xu, Zuoqin Yan, Ning Sun, Ruizhe Qian, 2016
Awards
  • 2018: First Prize in Shanghai Teaching Achievement Award (First Author)
  • 2015: Baosteel National Excellent Teacher Award
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