Professor | Gonghong Wei | Asia Growth Partners

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Name	Gonghong Wei
Contact Information	ngonghong_wei@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Gonghong Wei

Contact Information

ngonghong_wei@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1996.09—2000.07 Bachelor's Degree: Anhui Normal University, School of Life Sciences 2000.09—2003.07 Master's Degree: Capital Normal University, School of Life Sciences 2003.08—2006.09 Doctorate: Peking Union Medical College, School of Basic Medicine
Work Experience	2006.10—2011.10 - University of Helsinki, Faculty of Medicine - Postdoctoral Researcher 2011.11—2019.11 - University of Oulu, Faculty of Medicine - Young Researcher, Associate Professor, Professor 2014.9—2019.8 - Academy of Finland - Researcher 2016.9—2019.11 - Cancer Genomics Unit - Leader 2019.11—Present - Fudan University, School of Basic Medical Sciences - Distinguished Professor 2021.10—Present - Fudan University, Department of Biochemistry and Molecular Biology - Head
Awards	Medix Prize (2019): Detail Biocenter Oulu Discovery of the Year (2018): Detail Excellent doctoral thesis award of University of Oulu Medical School (2017): Detail Biocenter Oulu Discovery of the Year (2016): Detail Medix Prize (2015): Detail Biocenter Oulu Discovery of the Year (2014): Detail Pfizer Best Poster Award at International Biochemical Congress (IUBMB&FAOBMB) (2009): Detail Outstanding Graduate of Peking Union Medical College (2006): Detail

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1996.09—2000.07 Bachelor's Degree: Anhui Normal University, School of Life Sciences
2000.09—2003.07 Master's Degree: Capital Normal University, School of Life Sciences
2003.08—2006.09 Doctorate: Peking Union Medical College, School of Basic Medicine

Work Experience

2006.10—2011.10 - University of Helsinki, Faculty of Medicine - Postdoctoral Researcher
2011.11—2019.11 - University of Oulu, Faculty of Medicine - Young Researcher, Associate Professor, Professor
2014.9—2019.8 - Academy of Finland - Researcher
2016.9—2019.11 - Cancer Genomics Unit - Leader
2019.11—Present - Fudan University, School of Basic Medical Sciences - Distinguished Professor
2021.10—Present - Fudan University, Department of Biochemistry and Molecular Biology - Head

Awards

Medix Prize (2019): Detail
Biocenter Oulu Discovery of the Year (2018): Detail
Excellent doctoral thesis award of University of Oulu Medical School (2017): Detail
Biocenter Oulu Discovery of the Year (2016): Detail
Medix Prize (2015): Detail
Biocenter Oulu Discovery of the Year (2014): Detail
Pfizer Best Poster Award at International Biochemical Congress (IUBMB&FAOBMB) (2009): Detail
Outstanding Graduate of Peking Union Medical College (2006): Detail

Areas of Focus	Regulation of Gene Expression and Human Diseases Medical Genetics and Genomics Epigenetics and Systems Biology
Publications	Extensive germline-somatic interplay contributes to prostate cancer progression through HNF1B co-option of TMPRSS2-ERG, Nikolaos Giannareas1#, Qin Zhang1#, Xiayun Yang1#, Rong Na2#, Yijun Tian3, Yuehong Yang1, Xiaohao Ruan4, Da Huang4, Xiaoqun Yang5, Chaofu Wang5, Peng Zhang6, Aki Manninen1, Liang Wang4, Gong-Hong Wei, 2023 Genome-Wide 3'-UTR Single Nucleotide Polymorphism Association Study Identifies Significant Prostate Cancer Risk-Associated Functional Loci at 8p21.2 in Chinese Population, Zhang N, Huang D, Jiang G, Chen S, Ruan X, Chen H, Huang J, Liu A, Zhang W, Lin X, Wu Y, Zhang Q, Li J, Tsu JH, Wei GH, Na R, 2022 Single-cell transcriptomics reveals cell type diversity of human prostate, Chen Y, Zhang P, Liao J, Cheng J, Zhang Q, Li T, Zhang H, Jiang Y, Zhang F, Zeng Y, Mo L, Yan H, Liu D, Zhang Q, Zou C, Wei GH, Mo Z, 2022 Mechanistic insights into genetic susceptibility to prostate cancer, Tian P#, Zhong M#, Wei GH, 2021 CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer, Ahmed M#, Soares F#, Xia JH#, Yang Y, Li J, Guo H, Su P, Tian Y, Lee JH, Wang M, Akhtar N, Houlahan KE, Bosch A, Zhou S, Mazrooei P, Hua J, Chen S, Petricca J, Zeng Y, Davies A, Fraser M, Quigley DA, Feng F, Boutros PC, Lupien M, Zoubeidi A, Wang L, Walsh MJ, Wang T, Ren S, Wei GH, He HH, 2021 Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus, Gao P#, Xia JH#, Sipeky C, Dong XM, Zhang Q, Yang Y, Zhang P, Cruz SP, Zhang K, Zhu J, Lee HM, Suleman S, Giannareas N, Liu S; PRACTICAL Consortium, Tammela TLJ, Auvinen A, Wang X, Huang Q, Wang L, Manninen A, Vaarala MH, Wang L, Schleutker J, Wei GH, 2018 A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding, Huang Q#, Whitington T#, Gao P, Lindberg JF, Yang Y, Sun J, Väisänen MR, Szulkin R, Annala M, Yan J, Egevad LA, Zhang K, Lin R, Jolma A, Nykter M, Manninen A, Wiklund F, Vaarala MH, Visakorpi T, Xu J, Taipale J, Wei GH, 2014 Gene regulatory mechanisms underpinning prostate cancer susceptibility, Whitington T#, Gao P#, Song W, Ross-Adams H, Lamb AD, Yang Y, Svezia I, Klevebring D, Mills IG, Karlsson R, Halim S, Dunning MJ, Egevad L, Warren AY, Neal DE, Grönberg H, Lindberg J, Wei GH (joint supervision), Wiklund F, 2016 High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing, Zhang P#, Xia J#, Zhu J, Gao P, Tian YJ, Du M, Guo CY, Suleman S, Zhang Q, Kohli M, Tillmans L, Thibodeau SN, French AJ, Cerhan JR, Wang LD, Wei GH, Wang L, 2018 Synergistic interaction of HOXB13 and CIP2A predispose to aggressive prostate cancer, Sipeky C#, Gao P#, Zhang Q, Wang L, Ettala O, Talala K, Tammela TL, Auvinen A, Wiklund F, Wei GH, Schleutker J*, 2018

Areas of Focus

Regulation of Gene Expression and Human Diseases
Medical Genetics and Genomics
Epigenetics and Systems Biology

Publications

Extensive germline-somatic interplay contributes to prostate cancer progression through HNF1B co-option of TMPRSS2-ERG, Nikolaos Giannareas1#, Qin Zhang1#, Xiayun Yang1#, Rong Na2#, Yijun Tian3, Yuehong Yang1, Xiaohao Ruan4, Da Huang4, Xiaoqun Yang5, Chaofu Wang5, Peng Zhang6, Aki Manninen1, Liang Wang4, Gong-Hong Wei*, 2023
Genome-Wide 3'-UTR Single Nucleotide Polymorphism Association Study Identifies Significant Prostate Cancer Risk-Associated Functional Loci at 8p21.2 in Chinese Population, Zhang N, Huang D, Jiang G, Chen S, Ruan X, Chen H, Huang J, Liu A, Zhang W, Lin X, Wu Y, Zhang Q, Li J, Tsu JH*, Wei GH*, Na R*, 2022
Single-cell transcriptomics reveals cell type diversity of human prostate, Chen Y, Zhang P, Liao J, Cheng J, Zhang Q, Li T, Zhang H, Jiang Y, Zhang F, Zeng Y, Mo L, Yan H, Liu D, Zhang Q, Zou C*, Wei GH*, Mo Z*, 2022
Mechanistic insights into genetic susceptibility to prostate cancer, Tian P#, Zhong M#, Wei GH*, 2021
CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer, Ahmed M#, Soares F#, Xia JH#, Yang Y, Li J, Guo H, Su P, Tian Y, Lee JH, Wang M, Akhtar N, Houlahan KE, Bosch A, Zhou S, Mazrooei P, Hua J, Chen S, Petricca J, Zeng Y, Davies A, Fraser M, Quigley DA, Feng F, Boutros PC, Lupien M, Zoubeidi A, Wang L, Walsh MJ, Wang T, Ren S*, Wei GH*, He HH*, 2021
Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus, Gao P#, Xia JH#, Sipeky C, Dong XM, Zhang Q, Yang Y, Zhang P, Cruz SP, Zhang K, Zhu J, Lee HM, Suleman S, Giannareas N, Liu S; PRACTICAL Consortium, Tammela TLJ, Auvinen A, Wang X, Huang Q, Wang L, Manninen A, Vaarala MH, Wang L, Schleutker J, Wei GH*, 2018
A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding, Huang Q#, Whitington T#, Gao P, Lindberg JF, Yang Y, Sun J, Väisänen MR, Szulkin R, Annala M, Yan J, Egevad LA, Zhang K, Lin R, Jolma A, Nykter M, Manninen A, Wiklund F, Vaarala MH, Visakorpi T, Xu J, Taipale J*, Wei GH*, 2014
Gene regulatory mechanisms underpinning prostate cancer susceptibility, Whitington T#, Gao P#, Song W, Ross-Adams H, Lamb AD, Yang Y, Svezia I, Klevebring D, Mills IG, Karlsson R, Halim S, Dunning MJ, Egevad L, Warren AY, Neal DE, Grönberg H, Lindberg J, Wei GH (joint supervision), Wiklund F, 2016
High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing, Zhang P#, Xia J#, Zhu J, Gao P, Tian YJ, Du M, Guo CY, Suleman S, Zhang Q, Kohli M, Tillmans L, Thibodeau SN, French AJ, Cerhan JR, Wang LD*, Wei GH*, Wang L*, 2018
Synergistic interaction of HOXB13 and CIP2A predispose to aggressive prostate cancer, Sipeky C#, Gao P#, Zhang Q, Wang L, Ettala O, Talala K, Tammela TL, Auvinen A, Wiklund F, Wei GH*, Schleutker J*, 2018

Gene Expression Human Diseases Genetics Genomics Epigenetics Systems Biology Medical Research Biochemistry Molecular Biology Cancer Genomics

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