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Yanling Wu
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, English
Immune Molecules
Artificial Modification
Application
Directed Evolution
Synthetic
Tumor
Infectious Diseases
Treatment
Antibodies
Nanobodies
Areas of Focus
- Artificial modification and application of immune molecules
- Development and application of newly structured synthetic antibodies
Work Experience
- 2018.06 – 2020.08 - Fudan University - Postdoctoral Researcher
- 2020.09 – Present - Fudan University - Associate Researcher
- 2021.01 – Present - Shanghai Synthetic Immunology Engineering Technology Research Center - Deputy Director
Academic Background & Achievements
- 2008.09 – 2012.06 Bachelor's Degree (Biology): Liaoning Normal University
- 2012.09 – 2015.06 Master's Degree (Biology): Xinjiang University
- 2015.09 – 2018.06 Doctoral Degree (Basic Medicine): Fudan University
Publications
- Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody, Li, C., Zhan, W., Yang, Z., Tu, C., Hu, G., Zhang, X., Song, W., Du, S., Zhu, Y., Huang, K., Kong, Y., Zhang, M., Mao, Q., Gu, X., Zhang, Y., Xie, Y., Deng, Q., Song, Y., Chen, Z., Lu, L., Jiang, S., Wu, Y., Sun, L., Ying, T., 2022
- Design of a Novel Fab-Like Antibody Fragment with Enhanced Stability and Affinity for Clinical use, Wang, C., Hong, J., Yang, Z., Zhou, X., Yang, Y., Kong, Y., Chen, B., Wu, H., Qian, B. Z., Dimitrov, D. S., Zhou, X., Wu, Y., Ying, T., 2021
- The impact of receptor-binding domain natural mutations on antibody recognition of SARS-CoV-2, Li, C., Tian, X., Jia, X., Wan, J., Lu, L., Jiang, S., Lan, F., Lu, Y., Wu, Y., Ying, T., 2021
- Identification of Human Single-Domain Antibodies against SARS-CoV-2, Wu, Y., Li, C., Xia, S., Tian, X., Kong, Y., Wang, Z., Gu, C., Zhang, R., Tu, C., Xie, Y., Yang, Z., Lu, L., Jiang, S., Ying, T., 2020
- Rapid Elimination of Broadly Neutralizing Antibodies Correlates with Treatment Failure in the Acute Phase of Simian-Human Immunodeficiency Virus Infection, Wu, Y., Xue, J., Wang, C., Li, W., Wang, L., Chen, W., Prabakaran, P., Kong, D., Jin, Y., Hu, D., Wang, Y., Lei, C., Yu, D., Tu, C., Bardhi, A., Sidorov, I., Ma, L., Goldstein, H., Qin, C., Lu, L., Jiang, S., Dimitrov, D.S., Ying, T., 2019
Awards
- 2018: Shanghai 'Super Postdoctoral Fellow', Shanghai Human Resources and Social Security Bureau
- 2018: Shanghai Outstanding Graduate, Shanghai Municipal Education Commission
- 2018: One Health Fund Award, One Health Fund
- 2017: Antibodies 2017 Award, Antibodies
