Professor | Jian Wu | Asia Growth Partners

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Name	Jian Wu
Contact Information	jian.wu@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Jian Wu

Contact Information

jian.wu@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1978.8-1983.8 Bachelor of Medicine: Nantong University Medical School, China 1983.9-1986.7 Master of Medicine: Southeast University Medical School, China 1990.8-1994.12 Doctor of Medicine: Umeå University Medical School, Sweden 1995.6-1999.9 Postdoctoral: Thomas Jefferson University Medical School, USA 2003.1-6 Professional Development and Leadership Training: University of California, Davis Medical School, USA
Work Experience	1986.7-1990.8 - Southeast University Medical School Zhongda Hospital, China - Lecturer/Attending Physician 1990.8-1994.12 - Umeå University Medical School, Sweden - PhD Researcher/Assistant 1995.1-1995.5 - Umeå University Hospital, Sweden - Assistant Researcher 1995.6-1999.9 - Thomas Jefferson University Medical School, USA - Postdoctoral Scientist 1999.10-2005.6 - University of California, Davis Medical School, USA - Assistant Professor 2003-2014 - University of California, Davis Graduate School, USA - Doctoral Supervisor 2005.7-2009.6 - University of California, Davis Medical School, USA - Associate Professor 2009.7-2014.12 - University of California, Davis Medical School, USA - Professor 2009-2014.12 - University of California, Davis - Principal Investigator 2011.6-2012.9 - University of California, Davis - Chair of Career Development Committee 2011.11-2013.4 - Fudan University Affiliated Huashan Hospital, China - Distinguished Professor 2013.4—Present - Fudan University, China - Distinguished Professor/Fixed PI 2014.3—Present - Fudan University Shanghai Medical College-PerkinElmer Company - Executive Deputy Director 2014.3—Present - Shanghai Liver Disease Research Institute - Director 2019.7—Present - Fudan University Affiliated Zhongshan Hospital, China - Dual-appointed Professor 2019—Present - Fudan University Academic Norms Committee - Deputy Director 2014—Present - Fudan University Basic Medical College Ethics Committee - Deputy Director
Awards	National Institutes of Health National Research Service Award (1997): National level American Association for the Study of Liver Diseases and Liver Foundation 'Liver Scholar' Award (2000): National level Chinese Academy of Sciences Outstanding Overseas Chinese Scholar Short-term Research Award (2001) American Cancer Society Research Award (2004): National level National Institutes of Health Exploratory Research Award (2004): National level University of California, Davis Academic Federation Innovative Development Research Award (2006): University level University of California, Davis Medical Center Biotechnology Translation Award (2007): University level Nanjing Innovative Science and Technology Talent Award (2012) National Nano-Biotechnology and Medicine Technology Professional Committee Second Prize for Scientific Achievements (2013) American Association for the Study of Liver Diseases (AASLD) Fellow (2017)

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1978.8-1983.8 Bachelor of Medicine: Nantong University Medical School, China
1983.9-1986.7 Master of Medicine: Southeast University Medical School, China
1990.8-1994.12 Doctor of Medicine: Umeå University Medical School, Sweden
1995.6-1999.9 Postdoctoral: Thomas Jefferson University Medical School, USA
2003.1-6 Professional Development and Leadership Training: University of California, Davis Medical School, USA

Work Experience

1986.7-1990.8 - Southeast University Medical School Zhongda Hospital, China - Lecturer/Attending Physician
1990.8-1994.12 - Umeå University Medical School, Sweden - PhD Researcher/Assistant
1995.1-1995.5 - Umeå University Hospital, Sweden - Assistant Researcher
1995.6-1999.9 - Thomas Jefferson University Medical School, USA - Postdoctoral Scientist
1999.10-2005.6 - University of California, Davis Medical School, USA - Assistant Professor
2003-2014 - University of California, Davis Graduate School, USA - Doctoral Supervisor
2005.7-2009.6 - University of California, Davis Medical School, USA - Associate Professor
2009.7-2014.12 - University of California, Davis Medical School, USA - Professor
2009-2014.12 - University of California, Davis - Principal Investigator
2011.6-2012.9 - University of California, Davis - Chair of Career Development Committee
2011.11-2013.4 - Fudan University Affiliated Huashan Hospital, China - Distinguished Professor
2013.4—Present - Fudan University, China - Distinguished Professor/Fixed PI
2014.3—Present - Fudan University Shanghai Medical College-PerkinElmer Company - Executive Deputy Director
2014.3—Present - Shanghai Liver Disease Research Institute - Director
2019.7—Present - Fudan University Affiliated Zhongshan Hospital, China - Dual-appointed Professor
2019—Present - Fudan University Academic Norms Committee - Deputy Director
2014—Present - Fudan University Basic Medical College Ethics Committee - Deputy Director

Awards

National Institutes of Health National Research Service Award (1997): National level
American Association for the Study of Liver Diseases and Liver Foundation 'Liver Scholar' Award (2000): National level
Chinese Academy of Sciences Outstanding Overseas Chinese Scholar Short-term Research Award (2001)
American Cancer Society Research Award (2004): National level
National Institutes of Health Exploratory Research Award (2004): National level
University of California, Davis Academic Federation Innovative Development Research Award (2006): University level
University of California, Davis Medical Center Biotechnology Translation Award (2007): University level
Nanjing Innovative Science and Technology Talent Award (2012)
National Nano-Biotechnology and Medicine Technology Professional Committee Second Prize for Scientific Achievements (2013)
American Association for the Study of Liver Diseases (AASLD) Fellow (2017)

Areas of Focus	Microecological changes and persistent liver inflammation, metabolic abnormalities, and tumors Stem cell biology and liver regenerative medicine engineering Targeted drug, gene, and cell therapy for liver diseases Molecular basis and clinical diagnosis of liver cancer progression and metastasis
Publications	Novel aptasensor-based assay of sonic hedgehog ligand for detection of portal vein invasion of hepatocellular carcinoma, Hui-Yan Li, Fang-Fei Yin, Xin-Yi Li, Wan-Nan Jia, Jia Ding, Li Zhang, Zhong-Hua Wang, Qin-Qin Hu, Jie-Liang Zuo, Hu-Liang Jia, Li-Hua Wang, Chun-Hai Fan, Hong-Zhou Gu, Jian Wu, 2021 Thermo-responsive polymer encapsulated gold nanorods for single continuous wave laser-induced photodynamic/photothermal tumour therapy, Beilei Gong, Yuanbing Shen, Huiyan Li, Xiaojun Li, Xia Huan, Jihong Zhou, Yuqing Chen, Jian Wu, Wei Li, 2021 Serum Lipocalin-2 is a Potential Novel Biomarker for the Clinical Diagnosis of Nonalcoholic Steatohepatitis, Gang Xu, Yu-Min Wang, Miao-Miao Ying, Sui-Dan Chen, Zong-Rui Li, Hong-Lei Ma, Ming-Hua Zheng, Jian Wu, Chun-Ming Ding, 2021 Succinate-GPR-91 Receptor Signaling Is Responsible for Nonalcoholic Steatohepatitis-Associated Fibrosis: Effects of DHA Supplementation, Xue-Jing Liu, Li Xie, Kuo Du, Chang Liu, Ning-Ping Zhang, Chen-Jian Gu, Ying Wang, Manal F. Abdelmalek, Wen-Yue Dong, Xiu-Ping Liu, Chen Niu, Chen Yang, Anna Mae Diehl, Jian Wu, 2020 Impaired Mitophagy Triggers NLRP3 Inflammasome Activation during the Progression from Nonalcoholic Fatty Liver to Nonalcoholic Steatohepatitis, Ning-Ping Zhang, Xue-Jing Liu, Li Xie, Xi-Zhong Shen, Jian Wu, 2019 JCAD Is Associated with the Progression of Nonalcoholic Steatohepatitis to Malignancy via Inhibition of the Kinase Activity of LATS2 in Hippo Signaling, Juan Ye, Tian-Sheng Li, Gang Xu, Yi-Ming Zhao, Ning-Ping Zhang, Jia Fan, Jian Wu, 2017 Aberrant Hedgehog Signaling is responsible for the Highly Invasive Behavior of a Subpopulation of Hepatoma Cells, Ya-Han Fan, Jia Ding, Samantha Nguyen, Xue-Jing Liu, Gang Xu, Hao-Yu Zuo, Na-Na Duan, Si-Ming Yang, Mark A. Zern, Jian Wu, 2016 Epithelial Mesenchymal Transition and Hedgehog Signaling Activation are Associated with Chemoresistance and Enhanced Metastasis of Poorly-Differentiated Hepatoma Cells, Xiaoli Chen, Shilpa Lingala, Mark A. Zern, Jan Nolta, Jian Wu, 2011 Decellularized Liver Matrix as a Carrier for Transplantation of Human Fetal and Primary Hepatocytes in Mice, Ping Zhou, Nataly Lessa, Daniel C. Estrada, Ella B. Severson, Shilpa Lingala, Mark A. Zern, Jan Nolta, Jian Wu, 2011 Liposome-Mediated Extracellular Superoxide Dismutase Gene Delivery Protects against Acute Liver Injury in mice, Jian Wu, Li Liu, Roy D. Yen, Andreea Catana, Michael H. N

Areas of Focus

Microecological changes and persistent liver inflammation, metabolic abnormalities, and tumors
Stem cell biology and liver regenerative medicine engineering
Targeted drug, gene, and cell therapy for liver diseases
Molecular basis and clinical diagnosis of liver cancer progression and metastasis

Publications

Novel aptasensor-based assay of sonic hedgehog ligand for detection of portal vein invasion of hepatocellular carcinoma, Hui-Yan Li, Fang-Fei Yin, Xin-Yi Li, Wan-Nan Jia, Jia Ding, Li Zhang, Zhong-Hua Wang, Qin-Qin Hu, Jie-Liang Zuo, Hu-Liang Jia, Li-Hua Wang, Chun-Hai Fan, Hong-Zhou Gu, Jian Wu, 2021
Thermo-responsive polymer encapsulated gold nanorods for single continuous wave laser-induced photodynamic/photothermal tumour therapy, Beilei Gong, Yuanbing Shen, Huiyan Li, Xiaojun Li, Xia Huan, Jihong Zhou, Yuqing Chen, Jian Wu, Wei Li, 2021
Serum Lipocalin-2 is a Potential Novel Biomarker for the Clinical Diagnosis of Nonalcoholic Steatohepatitis, Gang Xu, Yu-Min Wang, Miao-Miao Ying, Sui-Dan Chen, Zong-Rui Li, Hong-Lei Ma, Ming-Hua Zheng, Jian Wu, Chun-Ming Ding, 2021
Succinate-GPR-91 Receptor Signaling Is Responsible for Nonalcoholic Steatohepatitis-Associated Fibrosis: Effects of DHA Supplementation, Xue-Jing Liu, Li Xie, Kuo Du, Chang Liu, Ning-Ping Zhang, Chen-Jian Gu, Ying Wang, Manal F. Abdelmalek, Wen-Yue Dong, Xiu-Ping Liu, Chen Niu, Chen Yang, Anna Mae Diehl, Jian Wu, 2020
Impaired Mitophagy Triggers NLRP3 Inflammasome Activation during the Progression from Nonalcoholic Fatty Liver to Nonalcoholic Steatohepatitis, Ning-Ping Zhang, Xue-Jing Liu, Li Xie, Xi-Zhong Shen, Jian Wu, 2019
JCAD Is Associated with the Progression of Nonalcoholic Steatohepatitis to Malignancy via Inhibition of the Kinase Activity of LATS2 in Hippo Signaling, Juan Ye, Tian-Sheng Li, Gang Xu, Yi-Ming Zhao, Ning-Ping Zhang, Jia Fan, Jian Wu, 2017
Aberrant Hedgehog Signaling is responsible for the Highly Invasive Behavior of a Subpopulation of Hepatoma Cells, Ya-Han Fan, Jia Ding, Samantha Nguyen, Xue-Jing Liu, Gang Xu, Hao-Yu Zuo, Na-Na Duan, Si-Ming Yang, Mark A. Zern, Jian Wu, 2016
Epithelial Mesenchymal Transition and Hedgehog Signaling Activation are Associated with Chemoresistance and Enhanced Metastasis of Poorly-Differentiated Hepatoma Cells, Xiaoli Chen, Shilpa Lingala, Mark A. Zern, Jan Nolta, Jian Wu, 2011
Decellularized Liver Matrix as a Carrier for Transplantation of Human Fetal and Primary Hepatocytes in Mice, Ping Zhou, Nataly Lessa, Daniel C. Estrada, Ella B. Severson, Shilpa Lingala, Mark A. Zern, Jan Nolta, Jian Wu, 2011
Liposome-Mediated Extracellular Superoxide Dismutase Gene Delivery Protects against Acute Liver Injury in mice, Jian Wu, Li Liu, Roy D. Yen, Andreea Catana, Michael H. N

Microecology Liver Inflammation Metabolic Abnormalities Tumors Stem Cell Biology Regenerative Medicine Targeted Therapy Gene Therapy Cell Therapy Liver Cancer

Yi Sun - Central South University

Yinzi - Zhejiang University

Zhou Jing - Zhejiang University

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