Areas of Focus
- Macrophage Biology: In-depth study of the molecular mechanisms and functional significance of abnormal macrophage reprogramming in autoimmune diseases and tumorigenesis, laying the foundation for developing immunotherapy strategies targeting abnormal macrophage reprogramming.
Work Experience
- 2010.07—2012.08 - Fudan University Shanghai Medical College - Postdoctoral Researcher
- 2012.09—2013.11 - Fudan University Basic Medical Sciences - Lecturer
- 2013.12—2019.11 - Fudan University Basic Medical Sciences - Associate Professor
- 2019.12—Present - Fudan University Basic Medical Sciences - Professor
Academic Background & Achievements
- 1997.09—2002.06 Bachelor's Degree: Sichuan University Huaxi Medical Center
- 2002.09—2005.06 Master's Degree: Sichuan University Huaxi Medical Center
- 2007.09—2010.06 Doctorate: Fudan University Shanghai Medical College
Publications
- Poor clinical outcomes and immunoevasive contexture in intratumoral IL10-producing macrophages enriched gastric cancer patients, Zhang H, Li R, Cao Y, Gu Y, Lin C, Liu X, Lv K, He X, Fang H, Jin K, Fei Y, Chen Y, Wang J, Liu H, Li H, Zhang H*, He H*, Zhang W*, 2022
- Intratumoral TIGIT+ CD8+ T cell infiltration determines poor prognosis and immune evasion in patients with muscle-invasive bladder cancer, Liu Z, Zhou Q, Wang Z, Zhang H, Zeng H, Huang Q, Chen Y, Jiang W, Lin Z, Qu Y, Xiong Y, Bai Q, Xia Y, Wang Y, Liu L, Zhu Y, Xu L, Dai B, Guo J, Wang J*, Chang Y*, Zhang W*, 2020
- Tumor-associated macrophages-derived CXCL8 determines immune evasion through autonomous PD-L1 expression in gastric cancer, Lin C, He H, Liu H, Li R, Chen Y, Qi Y, Jiang Q, Chen L, Zhang P, Zhang H, Li H, Zhang W*, Sun Y*, Xu J*, 2019
- Intratumoral IL17-producing cells infiltration correlate with anti-tumor immune contexture and improved response to adjuvant chemotherapy in gastric cancer, Wang JT, Li H, Zhang H, Chen YF, Cao YF, Li RC, Lin C, Wei YC, Xiang XN, Fang HJ, Zhang HY, Gu Y, Liu X, Zhou RJ, Liu H, He HY, Zhang WJ*, Shen ZB*, Qin J*, Xu JJ*, 2019
- Tumor-associated macrophage-derived IL-23 interlinks kidney cancer glutamine addiction with immune evasion, Fu Q, Xu L, Wang Y, Jiang Q, Liu Z, Zhang J, Zhou Q, Zeng H, Tong S, Qi Y, Hu B, Fu H, Xie H, Zhou L, Chang Y, Zhu Y, Dai B*, Zhang W*, Xu J*, 2019